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C-X-C chemokine receptor

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Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity.

Below are the list of possible C-X-C chemokine receptor products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

C-X-C chemokine receptor type 1

 C-X-C chemokine receptor type 1 ELISA Kit
 C-X-C chemokine receptor type 1 Recombinant
 C-X-C chemokine receptor type 1 Antibody
Also known as C-X-C chemokine receptor type 1 (CXC-R1) (CXCR-1) (CDw128a) (High affinity interleukin-8 receptor A) (IL-8R A) (IL-8 receptor type 1) (CD antigen CD181).
IL8RA: Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR
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, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR; Receptor, cytokine

Chromosomal Location of Human Ortholog: 2q35

Cellular Component: membrane; plasma membrane

Molecular Function: chemokine receptor activity; G-protein coupled receptor activity; interleukin-8 binding; interleukin-8 receptor activity

Biological Process: cell surface receptor linked signal transduction; chemotaxis; dendritic cell chemotaxis; inflammatory response; receptor internalization

Disease: Human Immunodeficiency Virus Type 1, Susceptibility To
 CXCR1 ELISA Kit
 CXCR1 Recombinant
 CXCR1 Antibody
 CMKAR1 ELISA Kit
 CMKAR1 Recombinant
 CMKAR1 Antibody
 IL8RA ELISA Kit
 IL8RA Recombinant
 IL8RA Antibody
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C-X-C chemokine receptor type 2

 C-X-C chemokine receptor type 2 ELISA Kit
 C-X-C chemokine receptor type 2 Recombinant
 C-X-C chemokine receptor type 2 Antibody
Also known as C-X-C chemokine receptor type 2 (CXC-R2) (CXCR-2) (CDw128b) (GRO/MGSA receptor) (High affinity interleukin-8 receptor B) (IL-8R B) (IL-8 receptor type 2) (CD antigen CD182).
IL8RB: Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a
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phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR; Receptor, cytokine

Chromosomal Location of Human Ortholog: 2q35

Cellular Component: cell surface; integral to plasma membrane; intracellular; mast cell granule; membrane; plasma membrane

Molecular Function: C-X-C chemokine receptor activity; interleukin-8 binding; interleukin-8 receptor activity; protein binding; signal transducer activity

Biological Process: cell surface receptor linked signal transduction; cellular defense response; chemotaxis; dendritic cell chemotaxis; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); inflammatory response; neutrophil activation; neutrophil chemotaxis; positive regulation of cell proliferation; receptor internalization; signal transduction
 CXCR2 ELISA Kit
 CXCR2 Recombinant
 CXCR2 Antibody
 IL8RB ELISA Kit
 IL8RB Recombinant
 IL8RB Antibody
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C-X-C chemokine receptor type 3

 C-X-C chemokine receptor type 3 ELISA Kit
 C-X-C chemokine receptor type 3 Recombinant
 C-X-C chemokine receptor type 3 Antibody
Also known as C-X-C chemokine receptor type 3 (CXC-R3) (CXCR-3) (CKR-L2) (G protein-coupled receptor 9) (Interferon-inducible protein 10 receptor) (IP-10 receptor) (CD antigen CD183).
CXCR3: Receptor for CXCL9, CXCL10 and CXCL11 and mediates the proliferation of human mesangial cells (HMC). Belongs to the G-protein coupled receptor 1 family. 3 isoforms of the human protein are produced by alter
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native splicing.

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: Xq13

Cellular Component: cytoplasm; integral to plasma membrane; plasma membrane

Molecular Function: chemokine binding; chemokine receptor activity

Biological Process: cell adhesion; cell motility; cell surface receptor linked signal transduction; chemotaxis
 CXCR3 ELISA Kit
 CXCR3 Recombinant
 CXCR3 Antibody
 GPR9 ELISA Kit
 GPR9 Recombinant
 GPR9 Antibody
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C-X-C chemokine receptor type 3-2

 C-X-C chemokine receptor type 3-2 ELISA Kit
 C-X-C chemokine receptor type 3-2 Recombinant
 C-X-C chemokine receptor type 3-2 Antibody
Receptor for the C-X-C chemokines cxcl11.1 and cxcl11.6 (PubMed:25573892). Promotes macrophage chemotaxis to sites of bacterial infection (PubMed:20424185, PubMed:25573892).
 cxcr3.2 ELISA Kit
 cxcr3.2 Recombinant
 cxcr3.2 Antibody
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C-X-C chemokine receptor type 4

 C-X-C chemokine receptor type 4 ELISA Kit
 C-X-C chemokine receptor type 4 Recombinant
 C-X-C chemokine receptor type 4 Antibody
Also known as C-X-C chemokine receptor type 4 (CXC-R4) (CXCR-4) (CD antigen CD184).
Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin; leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Involved in hematopoiesis an
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d in cardiac ventricular septum formation. Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival (). Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes ().
 CXCR4 ELISA Kit
 CXCR4 Recombinant
 CXCR4 Antibody
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C-X-C chemokine receptor type 4-A

 C-X-C chemokine receptor type 4-A ELISA Kit
 C-X-C chemokine receptor type 4-A Recombinant
 C-X-C chemokine receptor type 4-A Antibody
Also known as C-X-C chemokine receptor type 4-A (CXC-R4-A) (CXCR-4-A) (xCXCR4) (Stromal cell-derived factor 1 receptor A) (SDF-1 receptor A).
Receptor for the C-X-C chemokine cxcl12/sdf-1. Transduces a signal by increasing the intracellular level of calcium ions. Signaling with cxcl12/sdf-1 mediates the directional movement of mesodermal cells during gastrulation. May play a role in the migrati
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on of embryonic presumptive primordial germ cells (pPGCs). May also be involved in regulating the migration of hematopoietic stem cells into the larval liver.
 cxcr4-a ELISA Kit
 cxcr4-a Recombinant
 cxcr4-a Antibody
 cxcr4 ELISA Kit
 cxcr4 Recombinant
 cxcr4 Antibody
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C-X-C chemokine receptor type 4-B

 C-X-C chemokine receptor type 4-B ELISA Kit
 C-X-C chemokine receptor type 4-B Recombinant
 C-X-C chemokine receptor type 4-B Antibody
Also known as C-X-C chemokine receptor type 4-B (CXC-R4-B) (CXCR-4-B) (Stromal cell-derived factor 1 receptor B) (SDF-1 receptor B).
Receptor for the C-X-C chemokine cxcl12/sdf-1. Transduces a signal by increasing the intracellular level of calcium ions. Signaling with cxcl12/sdf-1 mediates the directional movement of mesodermal cells during gastrulation. May play a role in the migration of emb
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ryonic presumptive primordial germ cells (pPGCs). May also be involved in regulating migration of hematopoietic stem cells into the larval liver ().
 cxcr4-b ELISA Kit
 cxcr4-b Recombinant
 cxcr4-b Antibody
 cxcr4 ELISA Kit
 cxcr4 Recombinant
 cxcr4 Antibody
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C-X-C chemokine receptor type 5

 C-X-C chemokine receptor type 5 ELISA Kit
 C-X-C chemokine receptor type 5 Recombinant
 C-X-C chemokine receptor type 5 Antibody
Also known as C-X-C chemokine receptor type 5 (CXC-R5) (CXCR-5) (Burkitt lymphoma receptor 1 homolog) (CD antigen CD185).
CXCR5: Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation. Belongs to the G-protein coupled receptor 1 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: GPCR, family 1;
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Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Cellular Component: external side of plasma membrane

Biological Process: leukocyte chemotaxis; lymph node development; positive regulation of cytokinesis
 Cxcr5 ELISA Kit
 Cxcr5 Recombinant
 Cxcr5 Antibody
 Blr1 ELISA Kit
 Blr1 Recombinant
 Blr1 Antibody
 Gpcr6 ELISA Kit
 Gpcr6 Recombinant
 Gpcr6 Antibody
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C-X-C chemokine receptor type 6

 C-X-C chemokine receptor type 6 ELISA Kit
 C-X-C chemokine receptor type 6 Recombinant
 C-X-C chemokine receptor type 6 Antibody
Also known as C-X-C chemokine receptor type 6 (CXC-R6) (CXCR-6) (CD antigen CD186).
CXCR6: Receptor for the C-X-C chemokine CXCL16. Used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1. Belongs to the G-protein coupled receptor 1 family.

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Molecular Function: C-X
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-C chemokine binding; C-X-C chemokine receptor activity
 Cxcr6 ELISA Kit
 Cxcr6 Recombinant
 Cxcr6 Antibody
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