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Calcineurin B homologous protein

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Calcium-binding protein involved in different processes such as regulation of vesicular trafficking, plasma membrane Na(+)/H(+) exchanger and gene transcription. Involved in the constitutive exocytic membrane traffic. Mediates the association between microtubules and membrane-bound organelles of the endoplasmic reticulum and Golgi apparatus and is also required for the targeting and fusion of transcytotic vesicles (TCV) with the plasma membrane. Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exchange activity. Inhibits serum- and GTPase-stimulated Na(+)/H(+) exchange. Plays a role as an inhibitor of ribosomal RNA transcription. Acts as a negative regulator of the calcineurin/NFAT signaling pathway.

Below are the list of possible Calcineurin B homologous protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Calcineurin B homologous protein 1

 Calcineurin B homologous protein 1 ELISA Kit
 Calcineurin B homologous protein 1 Recombinant
 Calcineurin B homologous protein 1 Antibody
Also known as Calcineurin B homologous protein 1 (Calcineurin B-like protein) (Calcium-binding protein CHP) (Calcium-binding protein p22) (EF-hand calcium-binding domain-containing protein p22).
Calcium-binding protein involved in different processes such as regulation of vesicular trafficking, plasma membrane Na+/H+ exchanger and gene transcription. Involved in the constitutive exocytic membrane traffic. Mediates the association between microtubules and membrane-bound organelles of the endoplasmic reticulum and Golgi apparatus and is also required for the targeting and fusion of transcytot
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ic vesicles (TCV) with the plasma membrane. Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na+/H+ exchange activity. Inhibits serum- and GTPase-stimulated Na+/H+ exchange. Plays a role as an inhibitor of ribosomal RNA transcription. Acts as a negative regulator of the calcineurin/NFAT signaling pathway.
 CHP1 ELISA Kit
 CHP1 Recombinant
 CHP1 Antibody
 CHP ELISA Kit
 CHP Recombinant
 CHP Antibody
 RCJMB04_3d7 ELISA Kit
 RCJMB04_3d7 Recombinant
 RCJMB04_3d7 Antibody
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Calcineurin B homologous protein 2

 Calcineurin B homologous protein 2 ELISA Kit
 Calcineurin B homologous protein 2 Recombinant
 Calcineurin B homologous protein 2 Antibody
Also known as Calcineurin B homologous protein 2 (Chp-2).
CHP2: Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exchange activity. Binds to and activates SLC9A1/NHE1 in a serum-independent manner, thus increasing pH and protecting cells from serum deprivation- induced death. Also plays a role in the regulation of cell proliferation and tumo
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r growth by increasing the phosphatase activity of PPP3CA in a calcium-dependent manner. Activator of the calcineurin/NFAT signaling pathway. Involved in the cytoplasmic translocation of the transcription factor NFATC3 to the nucleus. Belongs to the calcineurin regulatory subunit family. CHP subfamily.

Cellular Component: cytoplasm; internal side of plasma membrane; nucleus; plasma membrane

Molecular Function: calcium ion binding; protein binding; protein domain specific binding

Biological Process: cellular sodium ion homeostasis; positive regulation of cell proliferation; positive regulation of protein import into nucleus; positive regulation of transcription from RNA polymerase II promoter; regulation of cellular pH
 Chp2 ELISA Kit
 Chp2 Recombinant
 Chp2 Antibody
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Calcineurin B homologous protein 3

 Calcineurin B homologous protein 3 ELISA Kit
 Calcineurin B homologous protein 3 Recombinant
 Calcineurin B homologous protein 3 Antibody
Also known as Calcineurin B homologous protein 3 (Tescalcin) (TE-1) (TSC).
TESC: Functions as an integral cofactor in cell pH regulation by controlling plasma membrane-type Na(+)/H(+) exchange activity. Promotes the maturation, transport, cell surface stability and exchange activity of SLC9A1/NHE1 at the plasma membrane. Promotes the induction of hematopoietic stem cell differentiation toward m
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egakaryocytic lineage. Essential for the coupling of ERK cascade activation with the expression of ETS family genes in megakaryocytic differentiation. Also involved in granulocytic differentiation in a ERK-dependent manner. Inhibits the phosphatase activity of calcineurin. Belongs to the calcineurin regulatory subunit family. CHP subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Cellular Component: cytoplasm; lamellipodium; nucleus; plasma membrane; ruffle

Molecular Function: calcium ion binding; magnesium ion binding; phosphatase inhibitor activity; protein homodimerization activity

Biological Process: cellular sodium ion homeostasis; male gonad development; megakaryocyte differentiation; negative regulation of cell proliferation; positive regulation of granulocyte differentiation; positive regulation of megakaryocyte differentiation; positive regulation of sodium:hydrogen antiporter activity; positive regulation of transcription, DNA-dependent; protein maturation; protein stabilization; regulation of cell adhesion mediated by integrin
 Tesc ELISA Kit
 Tesc Recombinant
 Tesc Antibody
 Chp3 ELISA Kit
 Chp3 Recombinant
 Chp3 Antibody
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