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Calcineurin-binding protein

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May be required for replication-independent chromatin assembly (By similarity). May serve as a negative regulator of T-cell receptor (TCR) signaling via inhibition of calcineurin.

Below are the list of possible Calcineurin-binding protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Calcineurin-binding protein cabin-1

 Calcineurin-binding protein cabin-1 ELISA Kit
 Calcineurin-binding protein cabin-1 Recombinant
 Calcineurin-binding protein cabin-1 Antibody
Also known as Calcineurin-binding protein cabin-1 (Calcineurin inhibitor) (CAIN).
CABIN1: an inhibitor of the calcium-dependent serine/threonine phosphatase, calcineurin. Inhibits calcineurin signaling in T cells, regulating T cell receptor (TCR) signaling, transcription, and apoptosis. Inhibition of activated calcineurin is dependent on both PKC and calcium signals. Represses myocyte enhancer
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factor 2 (MEF2)-mediated transcription by recruiting chromatin remodeling enzymes, and also negatively regulates the activity of the tumor suppressor p53. Is degraded in response to genotoxic stress, releasing its inhibition of p53, allowing p53 to elicit cellular stress responses. Involved in regulation of chromatin structure as part of the highly conserved HIRA/UBN1/CABIN1/ASF1A (HUCA) histone chaperone complex.

Protein type: Chaperone; Protein phosphatase, regulatory subunit; Transcription, coactivator/corepressor

Cellular Component: cytoplasm; nucleoplasm; nucleus

Molecular Function: nucleosome binding; protein binding; protein domain specific binding; protein phosphatase 2B binding; protein phosphatase inhibitor activity

Biological Process: DNA replication-independent nucleosome assembly; response to activity
 Cabin1 ELISA Kit
 Cabin1 Recombinant
 Cabin1 Antibody
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