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Calcium-activated potassium channel

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Potassium channel activated by both membrane depolarization or increase in cytosolic Ca(2+) that mediates export of K(+). Its activation dampens the excitatory events that elevate the cytosolic Ca(2+) concentration and/or depolarize the cell membrane. It therefore contributes to repolarization of the membrane potential. Plays a central role in synapses by regulating neurotransmitter release (By similarity).

Below are the list of possible Calcium-activated potassium channel products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Calcium-activated potassium channel slo-1

 Calcium-activated potassium channel slo-1 ELISA Kit
 Calcium-activated potassium channel slo-1 Recombinant
 Calcium-activated potassium channel slo-1 Antibody
Also known as Calcium-activated potassium channel slo-1 (BK channel) (Maxi K channel) (MaxiK) (Slo homolog) (Slowpoke protein 1).
Potassium channel activated by both membrane depolarization or increase in cytosolic Ca2+ that mediates export of K+. Its activation dampens the excitatory events that elevate the cytosolic Ca2+ concentration and/or depolarize the cell membrane. It therefore contribu
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tes to repolarization of the membrane potential. Plays a central role in synapses by regulating neurotransmitter release ().
 slo-1 ELISA Kit
 slo-1 Recombinant
 slo-1 Antibody
 Y51A2D.19 ELISA Kit
 Y51A2D.19 Recombinant
 Y51A2D.19 Antibody
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Calcium-activated potassium channel subunit alpha-1

 Calcium-activated potassium channel subunit alpha-1 ELISA Kit
 Calcium-activated potassium channel subunit alpha-1 Recombinant
 Calcium-activated potassium channel subunit alpha-1 Antibody
Also known as Calcium-activated potassium channel subunit alpha-1 (BK channel) (BKCA alpha) (Calcium-activated potassium channel, subfamily M subunit alpha-1) (K(VCA)alpha) (KCa1.1) (Maxi K channel) (MaxiK) (Slo-alpha) (Slo1) (mSlo1) (Slowpoke homolog) (Slo homolog) (mSlo).
Potassium channel activated by both membrane depolarization or increase in cytosolic Ca2+ that mediates export of K+. It i
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s also activated by the concentration of cytosolic Mg2+. Its activation dampens the excitatory events that elevate the cytosolic Ca2+ concentration and/or depolarize the cell membrane. It therefore contributes to repolarization of the membrane potential. Plays a key role in controlling excitability in a number of systems, such as regulation of the contraction of smooth muscle, the tuning of hair cells in the cochlea, regulation of transmitter release, and innate immunity. In smooth muscles, its activation by high level of Ca2+, caused by ryanodine receptors in the sarcoplasmic reticulum, regulates the membrane potential. In cochlea cells, its number and kinetic properties partly determine the characteristic frequency of each hair cell and thereby helps to establish a tonotopic map. Kinetics of KCNMA1 channels are determined by alternative splicing, phosphorylation status and its combination with modulating beta subunits. Highly sensitive to both iberiotoxin (IbTx) and charybdotoxin (CTX).
 Kcnma1 ELISA Kit
 Kcnma1 Recombinant
 Kcnma1 Antibody
 Kcnma ELISA Kit
 Kcnma Recombinant
 Kcnma Antibody
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Calcium-activated potassium channel subunit beta-1

 Calcium-activated potassium channel subunit beta-1 ELISA Kit
 Calcium-activated potassium channel subunit beta-1 Recombinant
 Calcium-activated potassium channel subunit beta-1 Antibody
Also known as Calcium-activated potassium channel subunit beta-1 (BK channel subunit beta-1) (BKbeta) (BKbeta1) (Calcium-activated potassium channel, subfamily M subunit beta-1) (Calcium-activated potassium channel subunit beta) (Charybdotoxin receptor subunit beta-1) (K(VCA)beta-1) (Maxi K channel subunit beta-1) (Slo-beta-1) (Slo-beta).
Regulatory subunit of the calcium activated potassium KC
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NMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Increases the apparent Ca2+/voltage sensitivity of the KCNMA1 channel. It also modifies KCNMA1 channel kinetics and alters its pharmacological properties. It slows down the activation and the deactivation kinetics of the channel. Acts as a negative regulator of smooth muscle contraction by enhancing the calcium sensitivity to KCNMA1. Its presence is also a requirement for internal binding of the KCNMA1 channel opener dehydrosoyasaponin I (DHS-1) triterpene glycoside and for external binding of the agonist hormone 17-beta-estradiol (E2). Increases the binding activity of charybdotoxin (CTX) toxin to KCNMA1 peptide blocker by increasing the CTX association rate and decreasing the dissociation rate ().
 KCNMB1 ELISA Kit
 KCNMB1 Recombinant
 KCNMB1 Antibody
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Calcium-activated potassium channel subunit beta-2

 Calcium-activated potassium channel subunit beta-2 ELISA Kit
 Calcium-activated potassium channel subunit beta-2 Recombinant
 Calcium-activated potassium channel subunit beta-2 Antibody
Also known as Calcium-activated potassium channel subunit beta-2 (BK channel subunit beta-2) (BKbeta2) (Calcium-activated potassium channel, subfamily M subunit beta-2) (Charybdotoxin receptor subunit beta-2) (K(VCA)beta-2) (Maxi K channel subunit beta-2) (Rbeta3) (Slo-beta-2).
a Ca(2+)-activated K(+) (BK) channel responsible for the large K(+) conductance in inner hair cells [RGD, Feb 2006]
 Kcnmb2 ELISA Kit
 Kcnmb2 Recombinant
 Kcnmb2 Antibody
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Calcium-activated potassium channel subunit beta-3

 Calcium-activated potassium channel subunit beta-3 ELISA Kit
 Calcium-activated potassium channel subunit beta-3 Recombinant
 Calcium-activated potassium channel subunit beta-3 Antibody
Also known as Calcium-activated potassium channel subunit beta-3 (BK channel subunit beta-3) (BKbeta3) (Hbeta3) (Calcium-activated potassium channel, subfamily M subunit beta-3) (Charybdotoxin receptor subunit beta-3) (K(VCA)beta-3) (Maxi K channel subunit beta-3) (Slo-beta-3).
KCNMB3: Regulatory subunit of the calcium activated potassium KCNMA1 (maxiK) channel. Modulates the calcium sensitivity and gating kinetics of KCNMA1, thereby contributing to KCNMA1 channel diversity. Alters the functional properties of the current expressed by the KCNMA1 channel. Isoform 2, isoform 3 and isoform 4 p
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artially inactivate the current of KCNBMA. Isoform 4 induces a fast and incomplete inactivation of KCNMA1 channel that is detectable only at large depolarizations. In contrast, isoform 1 does not induce detectable inactivation of KCNMA1. Two or more subunits of KCNMB3 are required to block the KCNMA1 tetramer. Belongs to the KCNMB (TC 8.A.14.1) family. KCNMB3 subfamily. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 3q26.3-q27

Cellular Component: integral to plasma membrane; plasma membrane; voltage-gated potassium channel complex

Molecular Function: calcium-activated potassium channel activity

Biological Process: detection of calcium ion; generation of action potential; potassium ion transport; regulation of action potential; synaptic transmission
 KCNMB3 ELISA Kit
 KCNMB3 Recombinant
 KCNMB3 Antibody
 KCNMB2 ELISA Kit
 KCNMB2 Recombinant
 KCNMB2 Antibody
 KCNMBL ELISA Kit
 KCNMBL Recombinant
 KCNMBL Antibody
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Calcium-activated potassium channel subunit beta-4

 Calcium-activated potassium channel subunit beta-4 ELISA Kit
 Calcium-activated potassium channel subunit beta-4 Recombinant
 Calcium-activated potassium channel subunit beta-4 Antibody
Also known as Calcium-activated potassium channel subunit beta-4 (BK channel subunit beta-4) (BKbeta4) (Calcium-activated potassium channel, subfamily M subunit beta-4) (Charybdotoxin receptor subunit beta-4) (K(VCA)beta-4) (Maxi K channel subunit beta-4) (Slo-beta-4).
mouse homolog is a subunit of the large conductance calcium-dependent potassium channel; downregulates channel activity [RGD, F
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eb 2006]
 Kcnmb4 ELISA Kit
 Kcnmb4 Recombinant
 Kcnmb4 Antibody
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