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Calpain

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Calpains are calcium-activated non-lysosomal thiol-proteases.

Below are the list of possible Calpain products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Calpain

 Calpain ELISA Kit
 Calpain Recombinant
 Calpain Antibody
Also known as Calpain (Calcium-activated neutral proteinase) (CANP).
Calpains are calcium-activated non-lysosomal thiol-proteases.
Table BarTOPTable Bar
 

Calpain 11

 Calpain 11 ELISA Kit
 Calpain 11 Recombinant
 Calpain 11 Antibody
Also known as Calpain 11 (Calcium-activated neutral proteinase 11) (CANP 11).
member of the serine protease family [RGD, Feb 2006]
 Capn11 ELISA Kit
 Capn11 Recombinant
 Capn11 Antibody
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Calpain clp-1

 Calpain clp-1 ELISA Kit
 Calpain clp-1 Recombinant
 Calpain clp-1 Antibody
Calcium-regulated protease involved in necrotic cell death.
 clp-1 ELISA Kit
 clp-1 Recombinant
 clp-1 Antibody
 C06G4.2/C06G4.3 ELISA Kit
 C06G4.2/C06G4.3 Recombinant
 C06G4.2/C06G4.3 Antibody
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Calpain small subunit 1

 Calpain small subunit 1 ELISA Kit
 Calpain small subunit 1 Recombinant
 Calpain small subunit 1 Antibody
Also known as Calpain small subunit 1 (CSS1) (Calcium-activated neutral proteinase small subunit) (CANP small subunit) (Calcium-dependent protease small subunit) (CDPS) (Calcium-dependent protease small subunit 1) (Calpain regulatory subunit).
CAPNS1: Regulatory subunit of the calcium-regulated non- lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction.

Protein type: Motility/polarity/chemotaxis; Protease

Chromosomal Location of Human Ortholog: 19q13.12

Cellular Component: cytosol; membrane
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Molecular Function: calcium-dependent cysteine-type endopeptidase activity; protein binding

Biological Process: extracellular matrix disassembly; positive regulation of cell proliferation
 CAPNS1 ELISA Kit
 CAPNS1 Recombinant
 CAPNS1 Antibody
 CAPN4 ELISA Kit
 CAPN4 Recombinant
 CAPN4 Antibody
 CAPNS ELISA Kit
 CAPNS Recombinant
 CAPNS Antibody
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Calpain small subunit 2

 Calpain small subunit 2 ELISA Kit
 Calpain small subunit 2 Recombinant
 Calpain small subunit 2 Antibody
Also known as Calpain small subunit 2 (CSS2) (Calcium-dependent protease small subunit 2).
CAPNS2: Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. This small subunit may act as a tissue-specific chaperone of the large subunit, possibly by helping it fold into its correct conformation fo
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r activity.

Cellular Component: cytoplasm

Molecular Function: calcium-dependent cysteine-type endopeptidase activity

Biological Process: proteolysis
 Capns2 ELISA Kit
 Capns2 Recombinant
 Capns2 Antibody
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Calpain-1 catalytic subunit

 Calpain-1 catalytic subunit ELISA Kit
 Calpain-1 catalytic subunit Recombinant
 Calpain-1 catalytic subunit Antibody
Also known as Calpain-1 catalytic subunit (Calcium-activated neutral proteinase 1) (CANP 1) (Calpain mu-type) (Calpain-1 large subunit) (Cell proliferation-inducing gene 30 protein) (Micromolar-calpain) (muCANP).
CAPN1: Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Forms a heterodimer with a small (regulatory) subunit (CAPNS1). Ubiquitous. Activated by micromolar concentrations of calcium and inhibited by calpastatin. Belongs to the peptidase C2 family.

Protein type: EC 3.4.
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22.52; Motility/polarity/chemotaxis; Protease

Chromosomal Location of Human Ortholog: 11q13

Cellular Component: cytoplasm; cytosol; focal adhesion; membrane; plasma membrane

Molecular Function: calcium-dependent cysteine-type endopeptidase activity; protein binding

Biological Process: extracellular matrix disassembly; positive regulation of cell proliferation; proteolysis

Disease: Spastic Paraplegia 76, Autosomal Recessive
 CAPN1 ELISA Kit
 CAPN1 Recombinant
 CAPN1 Antibody
 CANPL1 ELISA Kit
 CANPL1 Recombinant
 CANPL1 Antibody
 PIG30 ELISA Kit
 PIG30 Recombinant
 PIG30 Antibody
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Calpain-10

 Calpain-10 ELISA Kit
 Calpain-10 Recombinant
 Calpain-10 Antibody
Also known as Calpain-10 (Calcium-activated neutral proteinase 10) (CANP 10).
CAPN10: Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Defects in CAPN10 are a cause of susceptibility to diabetes mellitus non-insulin-dependent type 1 (NIDDM1). It is a multifactorial disorder of glucose hom
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eostasis caused by a lack of sensitivity to the body's own insulin. Affected individuals usually have an obese body habitus and manifestations of a metabolic syndrome characterized by diabetes, insulin resistance, hypertension and hypertriglyceridemia. The disease results in long-term complications that affect the eyes, kidneys, nerves, and blood vessels. Belongs to the peptidase C2 family. 8 isoforms of the human protein are produced by alternative splicing.

Protein type: Apoptosis; EC 3.4.22.-; Mitochondrial; Protease

Cellular Component: cell; cell cortex; cytoplasm; cytoskeleton; cytosol; intracellular membrane-bound organelle; mitochondrial inner membrane; mitochondrial intermembrane space; mitochondrial matrix; mitochondrial outer membrane; mitochondrion; nucleus; plasma membrane

Molecular Function: calcium-dependent cysteine-type endopeptidase activity; cytoskeletal protein binding; SNARE binding

Biological Process: actin cytoskeleton reorganization; aging; cellular response to insulin stimulus; mitochondrion degradation; mitochondrion organization and biogenesis; positive regulation of apoptosis; positive regulation of glucose import; positive regulation of insulin secretion; positive regulation of intracellular transport; proteolysis; response to nutrient levels
 Capn10 ELISA Kit
 Capn10 Recombinant
 Capn10 Antibody
 Capn8 ELISA Kit
 Capn8 Recombinant
 Capn8 Antibody
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Calpain-11

 Calpain-11 ELISA Kit
 Calpain-11 Recombinant
 Calpain-11 Antibody
Also known as Calpain-11 (Calcium-activated neutral proteinase 11) (CANP 11).
CAPN11: Calcium-regulated non-lysosomal thiol-protease which catalyzes limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Belongs to the peptidase C2 family.

Protein type: EC 3.4.22.-; Protease

Cellular Component: acrosome

Molecular Function: calcium-dep
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endent cysteine-type endopeptidase activity

Biological Process: proteolysis
 Capn11 ELISA Kit
 Capn11 Recombinant
 Capn11 Antibody
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Calpain-12

 Calpain-12 ELISA Kit
 Calpain-12 Recombinant
 Calpain-12 Antibody
Also known as Calpain-12 (Calcium-activated neutral proteinase 12) (CANP 12).
CAPN12: Calcium-regulated non-lysosomal thiol-protease. Belongs to the peptidase C2 family.

Protein type: EC 3.4.22.-; Protease

Cellular Component: cytoplasm

Molecular Function: calcium-dependent cysteine-type endopeptidase activity

Biological Process: proteolysis
 Capn12 ELISA Kit
 Capn12 Recombinant
 Capn12 Antibody
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Calpain-13

 Calpain-13 ELISA Kit
 Calpain-13 Recombinant
 Calpain-13 Antibody
Also known as Calpain-13 (Calcium-activated neutral proteinase 13) (CANP 13).
CAPN13: Probable non-lysosomal thiol-protease. Belongs to the peptidase C2 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.4.22.-; Protease

Cellular Component: cytoplasm

Molecular Function: calcium-dependent cysteine-type endopeptidase activity
<
>>>
br>Biological Process: proteolysis
 Capn13 ELISA Kit
 Capn13 Recombinant
 Capn13 Antibody
 Gm943 ELISA Kit
 Gm943 Recombinant
 Gm943 Antibody
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Calpain-14

 Calpain-14 ELISA Kit
 Calpain-14 Recombinant
 Calpain-14 Antibody
Also known as Calpain-14 (Calcium-activated neutral proteinase 14) (CANP 14).
Calpains are a family of cytosolic calcium-activated cysteine proteases involved in a variety of cellular processes including apoptosis, cell division, modulation of integrin-cytoskeletal interactions, and synaptic plasticity (Dear et al., 2000 [PubMed 10964513]). CAPN14 belongs to the calpain large subunit family.[su
>>>
pplied by OMIM, Mar 2008]
 CAPN14 ELISA Kit
 CAPN14 Recombinant
 CAPN14 Antibody
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Calpain-15

 Calpain-15 ELISA Kit
 Calpain-15 Recombinant
 Calpain-15 Antibody
Also known as Calpain-15 (Small optic lobes homolog).
SOLH: a protein containing zinc-finger-like repeats and a calpain-like protease domain. The encoded protein may function as a transcription factor, RNA-binding protein, or in protein-protein interactions during visual system development. [provided by RefSeq, Jul 2008]

Protein type: EC 3.4.22.-; Protease; Transcription factor

Ch
>>>
romosomal Location of Human Ortholog: 16p13.3

Cellular Component: cytoplasm

Molecular Function: cysteine-type peptidase activity; peptidase activity; transcription factor activity
 CAPN15 ELISA Kit
 CAPN15 Recombinant
 CAPN15 Antibody
 SOLH ELISA Kit
 SOLH Recombinant
 SOLH Antibody
Table BarTOPTable Bar
 

Calpain-2 catalytic subunit

 Calpain-2 catalytic subunit ELISA Kit
 Calpain-2 catalytic subunit Recombinant
 Calpain-2 catalytic subunit Antibody
Also known as Calpain-2 catalytic subunit (80 kDa M-calpain subunit) (CALP80) (Calcium-activated neutral proteinase 2) (CANP 2) (Calpain M-type) (Calpain-2 large subunit) (Millimolar-calpain) (M-calpain).
CAPN2: Calcium-regulated non-lysosomal thiol-protease which catalyze limited proteolysis of substrates involved in cytoskeletal remodeling and signal transduction. Forms a heterodimer with a s
>>>
mall (regulatory) subunit (CAPNS1). Ubiquitous. Activated by 200-1000 micromolar concentrations of calcium and inhibited by calpastatin. Belongs to the peptidase C2 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.4.22.53; Motility/polarity/chemotaxis; Protease

Cellular Component: chromatin; cytoplasm; cytosol; dendrite; endoplasmic reticulum; focal adhesion; Golgi apparatus; lipid raft; lysosome; nucleus; plasma membrane; pseudopodium

Molecular Function: calcium ion binding; calcium-dependent cysteine-type endopeptidase activity; cytoskeletal protein binding; peptidase activity; protein heterodimerization activity

Biological Process: blastocyst development; myoblast fusion; protein autoprocessing; proteolysis; proteolysis involved in cellular protein catabolic process
 Capn2 ELISA Kit
 Capn2 Recombinant
 Capn2 Antibody
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Calpain-3

 Calpain-3 ELISA Kit
 Calpain-3 Recombinant
 Calpain-3 Antibody
Also known as Calpain-3 (Calcium-activated neutral proteinase 3) (CANP 3) (Calpain L3) (Calpain p94) (Cn94) (Muscle-specific calcium-activated neutral protease 3).
Calcium-regulated non-lysosomal thiol-protease.
 CAPN3 ELISA Kit
 CAPN3 Recombinant
 CAPN3 Antibody
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Calpain-5

 Calpain-5 ELISA Kit
 Calpain-5 Recombinant
 Calpain-5 Antibody
CAPN5: Calpains are calcium-dependent cysteine proteases involved in signal transduction in a variety of cellular processes. A functional calpain protein consists of an invariant small subunit and 1 of a family of large subunits. CAPN5 is one of the large subunits. Unlike some of the calpains, CAPN5 and CAPN6 lack a calmodulin-like domain IV. Because of the significant similarity to Caenorhabditis
>>>
elegans sex determination gene tra-3, CAPN5 is also called as HTRA3. [provided by RefSeq, Jul 2008]

Protein type: EC 3.4.22.-; Protease

Cellular Component: cell surface; cytoplasm; focal adhesion

Molecular Function: calcium-dependent cysteine-type endopeptidase activity

Biological Process: granulosa cell differentiation; luteinization; ovarian follicle development; proteolysis
 Capn5 ELISA Kit
 Capn5 Recombinant
 Capn5 Antibody
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Calpain-6

 Calpain-6 ELISA Kit
 Calpain-6 Recombinant
 Calpain-6 Antibody
CAPN6: Microtubule-stabilizing protein that may be involved in the regulation of microtubule dynamics and cytoskeletal organization. May act as a regulator of RAC1 activity through interaction with ARHGEF2 to control lamellipodial formation and cell mobility. Does not seem to have protease activity as it has lost the active site residues. Belongs to the peptidase C2 family.

Cellular Compone
>>>
nt: cytoplasm; microtubule; perinuclear region of cytoplasm; spindle microtubule

Molecular Function: calcium-dependent cysteine-type endopeptidase activity; microtubule binding; protein binding

Biological Process: microtubule bundle formation; proteolysis; regulation of cytoskeleton organization and biogenesis
 Capn6 ELISA Kit
 Capn6 Recombinant
 Capn6 Antibody
 Capa6 ELISA Kit
 Capa6 Recombinant
 Capa6 Antibody
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Calpain-7

 Calpain-7 ELISA Kit
 Calpain-7 Recombinant
 Calpain-7 Antibody
Calcium-regulated non-lysosomal thiol-protease.
 CAPN7 ELISA Kit
 CAPN7 Recombinant
 CAPN7 Antibody
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Calpain-8

 Calpain-8 ELISA Kit
 Calpain-8 Recombinant
 Calpain-8 Antibody
Also known as Calpain-8 (Calpain large subunit 4) (New calpain 2) (nCL-2) (Stomach-specific M-type calpain).
CAPN8: Calcium-regulated non-lysosomal thiol-protease. Involved in membrane trafficking in the gastric surface mucus cells (pit cells) and may involve the membrane trafficking of mucus cells via interactions with coat protein. Proteolytically cleaves the beta- subunit of coatomer complex. Belongs to the peptidase C2 family.

Protein type: EC 3.4.22.53; Motility/polarity/chemotaxis; Protease

Cellular Component: cytoplasm

Molecular Function: calcium-dependent cystei
>>>
ne-type endopeptidase activity

Biological Process: proteolysis
 Capn8 ELISA Kit
 Capn8 Recombinant
 Capn8 Antibody
 Cls4 ELISA Kit
 Cls4 Recombinant
 Cls4 Antibody
 Ncl2 ELISA Kit
 Ncl2 Recombinant
 Ncl2 Antibody
Table BarTOPTable Bar
 

Calpain-9

 Calpain-9 ELISA Kit
 Calpain-9 Recombinant
 Calpain-9 Antibody
Also known as Calpain-9 (Digestive tract-specific calpain) (New calpain 4) (nCL-4).
member of the calpain large subunit family; predicted to have calpain cysteine protease activity [RGD, Feb 2006]
 Capn9 ELISA Kit
 Capn9 Recombinant
 Capn9 Antibody
 Ncl4 ELISA Kit
 Ncl4 Recombinant
 Ncl4 Antibody
Table BarTOPTable Bar
 

Calpain-A

 Calpain-A ELISA Kit
 Calpain-A Recombinant
 Calpain-A Antibody
Also known as Calpain-A (Calcium-activated neutral proteinase A) (CANP A).
Calcium-regulated non-lysosomal thiol-protease. Involved in the organization of the actin-related cytoskeleton during embryogenesis.
 CalpA ELISA Kit
 CalpA Recombinant
 CalpA Antibody
 CG7563 ELISA Kit
 CG7563 Recombinant
 CG7563 Antibody
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Calpain-B

 Calpain-B ELISA Kit
 Calpain-B Recombinant
 Calpain-B Antibody
Also known as Calpain-B (Calcium-activated neutral proteinase B) (CANP B).
Calcium-regulated non-lysosomal thiol-protease.
 CalpB ELISA Kit
 CalpB Recombinant
 CalpB Antibody
 CG8107 ELISA Kit
 CG8107 Recombinant
 CG8107 Antibody
Table BarTOPTable Bar
 

Calpain-C

 Calpain-C ELISA Kit
 Calpain-C Recombinant
 Calpain-C Antibody
Also known as Calpain-C (Calcium-activated neutral proteinase homolog C) (CANP C).
Not known; does not seem to have protease activity.
 CalpC ELISA Kit
 CalpC Recombinant
 CalpC Antibody
 CG3692 ELISA Kit
 CG3692 Recombinant
 CG3692 Antibody
Table BarTOPTable Bar
 

Calpain-D

 Calpain-D ELISA Kit
 Calpain-D Recombinant
 Calpain-D Antibody
Also known as Calpain-D (Calcium-activated neutral proteinase D) (CANP D) (Small optic lobes protein).
Has a role in eye development.
 sol ELISA Kit
 sol Recombinant
 sol Antibody
 CalpD ELISA Kit
 CalpD Recombinant
 CalpD Antibody
 CG1391 ELISA Kit
 CG1391 Recombinant
 CG1391 Antibody
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Proteins Root Name Listing
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