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Calsenilin

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Calcium-dependent transcriptional repressor that binds to the DRE element of genes including PDYN and FOS. Affinity for DNA is reduced upon binding to calcium and enhanced by binding to magnesium. Seems to be involved in nociception.

Below are the list of possible Calsenilin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Calsenilin

 Calsenilin ELISA Kit
 Calsenilin Recombinant
 Calsenilin Antibody
Also known as Calsenilin (A-type potassium channel modulatory protein 3) (DRE-antagonist modulator) (DREAM) (Kv channel-interacting protein 3) (KChIP3).
calsenilin: a small calcium-binding protein. Member of the family of voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs), which belong to the recoverin branch of the EF-hand superfamily. Modulates K4 voltage-gated potassium channels. May regulate A-type currents, and hence neuronal excitability, in response to changes in intracellular calcium. Also functions as a calcium-regulated transcriptional repressor, and to interact wi
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th presenilins. May play a role in the regulation of PSEN2 proteolytic processing.

Protein type: Calcium-binding; Transcription factor

Cellular Component: axon; cytosol; dendrite; nerve terminal; nucleus; voltage-gated potassium channel complex

Molecular Function: calcium-dependent protein binding; DNA binding; potassium channel regulator activity; protein C-terminus binding; sequence-specific DNA binding

Biological Process: behavioral response to pain; intracellular protein transport; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; potassium ion transport; regulation of neuron apoptosis; response to pain; sensory perception of pain
 Kcnip3 ELISA Kit
 Kcnip3 Recombinant
 Kcnip3 Antibody
 Csen ELISA Kit
 Csen Recombinant
 Csen Antibody
 Dream ELISA Kit
 Dream Recombinant
 Dream Antibody
 Kchip3 ELISA Kit
 Kchip3 Recombinant
 Kchip3 Antibody
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Calsenilin isoform 4

 Calsenilin isoform 4 ELISA Kit
 Calsenilin isoform 4 Recombinant
 Calsenilin isoform 4 Antibody
Calsenilin isoform 4: Unknown for isoform 4. Csen is involved in calcium-dependent transcriptional repression, regulation of potassium channels, and perhaps in processing of PSEN2 and apoptosis.

Cellular Component: axon; cytosol; dendrite; nerve terminal; nucleus; voltage-gated potassium channel complex

Molecular Function: calcium-dependent protein binding; DNA binding; potassium channel regulator activity; protein C-terminus binding; sequence-specific DNA binding

Biological Process: behavioral response to pain; intracellular protein transport; negative regulation of trans
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cription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; potassium ion transport; regulation of neuron apoptosis; response to pain; sensory perception of pain
 Kcnip3 ELISA Kit
 Kcnip3 Recombinant
 Kcnip3 Antibody
 Csen ELISA Kit
 Csen Recombinant
 Csen Antibody
 Dream ELISA Kit
 Dream Recombinant
 Dream Antibody
 Kchip3 ELISA Kit
 Kchip3 Recombinant
 Kchip3 Antibody
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