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CAP-Gly domain-containing linker protein

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Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth and microtubule bundling. Links cytoplasmic vesicles to microtubules and thereby plays an important role in intracellular vesicle trafficking. Plays a role macropinocytosis and endosome trafficking.

Below are the list of possible CAP-Gly domain-containing linker protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

CAP-Gly domain-containing linker protein 1

 CAP-Gly domain-containing linker protein 1 ELISA Kit
 CAP-Gly domain-containing linker protein 1 Recombinant
 CAP-Gly domain-containing linker protein 1 Antibody
Also known as CAP-Gly domain-containing linker protein 1 (Cytoplasmic linker protein 1) (Cytoplasmic linker protein 170 alpha-2) (CLIP-170) (Reed-Sternberg intermediate filament-associated protein) (Restin).
Restin: Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth and microtubule bundling. Links cytoplasmic vesicles to microtubules and thereby plays an important role in intracellular vesicle trafficking. Plays a role macropinocytosis and endosome trafficking. Interacts with MTOR; phosphorylates and regulates CLIP1.
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Interacts (via CAP-Gly domains) with tubulin. Interacts with SLAIN2. Interacts (via zinc finger) with DCTN1. Interacts with MAPRE1 and MAPRE3. Detected in dendritic cells. Highly expressed in the Reed-Sternberg cells of Hodgkin disease. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytoskeletal

Chromosomal Location of Human Ortholog: 12q24.3

Cellular Component: centrosome; cytoplasm; cytosol; endosome; intermediate filament; kinetochore; microtubule; microtubule cytoskeleton

Molecular Function: microtubule binding; microtubule plus-end binding; protein binding; protein homodimerization activity; tubulin binding; zinc ion binding

Biological Process: microtubule bundle formation; mitosis; positive regulation of microtubule polymerization; sister chromatid cohesion
 CLIP1 ELISA Kit
 CLIP1 Recombinant
 CLIP1 Antibody
 CYLN1 ELISA Kit
 CYLN1 Recombinant
 CYLN1 Antibody
 RSN ELISA Kit
 RSN Recombinant
 RSN Antibody
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CAP-Gly domain-containing linker protein 1 homolog

 CAP-Gly domain-containing linker protein 1 homolog ELISA Kit
 CAP-Gly domain-containing linker protein 1 homolog Recombinant
 CAP-Gly domain-containing linker protein 1 homolog Antibody
 clip-1 ELISA Kit
 clip-1 Recombinant
 clip-1 Antibody
 M01A8.2 ELISA Kit
 M01A8.2 Recombinant
 M01A8.2 Antibody
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CAP-Gly domain-containing linker protein 2

 CAP-Gly domain-containing linker protein 2 ELISA Kit
 CAP-Gly domain-containing linker protein 2 Recombinant
 CAP-Gly domain-containing linker protein 2 Antibody
Also known as CAP-Gly domain-containing linker protein 2 (Cytoplasmic linker protein 115) (CLIP-115) (Cytoplasmic linker protein 2).
CYLN2: Seems to link microtubules to dendritic lamellar body (DLB), a membranous organelle predominantly present in bulbous dendritic appendages of neurons linked by dendrodendritic gap junctions. May operate in the control of brain-specific organelle translocatio
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ns. CLIP2 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region. Haploinsufficiency of CLIP2 may be the cause of certain cardiovascular and musculo-skeletal abnormalities observed in the disease. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cytoskeletal; Motility/polarity/chemotaxis

Cellular Component: cytoplasmic microtubule; dendrite; lamellar body

Molecular Function: microtubule binding; microtubule plus-end binding; protein binding
 Clip2 ELISA Kit
 Clip2 Recombinant
 Clip2 Antibody
 Cyln2 ELISA Kit
 Cyln2 Recombinant
 Cyln2 Antibody
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CAP-Gly domain-containing linker protein 3

 CAP-Gly domain-containing linker protein 3 ELISA Kit
 CAP-Gly domain-containing linker protein 3 Recombinant
 CAP-Gly domain-containing linker protein 3 Antibody
Also known as CAP-Gly domain-containing linker protein 3 (Cytoplasmic linker protein 170-related 59 kDa protein) (CLIP-170-related 59 kDa protein) (CLIPR-59).
CLIPR-59: Functions as a cytoplasmic linker protein. Involved in TGN-endosome dynamics.

Protein type: Unknown function

Cellular Component: early endosome membrane; lipid raft; plasma membrane; recycling endosome membrane; tr
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ans-Golgi network; trans-Golgi network membrane

Molecular Function: microtubule binding; protein binding

Biological Process: fat cell differentiation; negative regulation of microtubule polymerization; peptidyl-S-palmitoyl-L-cysteine biosynthetic process from peptidyl-cysteine; positive regulation of apoptosis; positive regulation of endocytosis; positive regulation of protein amino acid phosphorylation
 Clip3 ELISA Kit
 Clip3 Recombinant
 Clip3 Antibody
 Clipr59 ELISA Kit
 Clipr59 Recombinant
 Clipr59 Antibody
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CAP-Gly domain-containing linker protein 4

 CAP-Gly domain-containing linker protein 4 ELISA Kit
 CAP-Gly domain-containing linker protein 4 Recombinant
 CAP-Gly domain-containing linker protein 4 Antibody
Also known as CAP-Gly domain-containing linker protein 4 (Restin-like protein 2).
CLIP4: 4 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 2p23.2

Molecular Function: protein binding
 CLIP4 ELISA Kit
 CLIP4 Recombinant
 CLIP4 Antibody
 RSNL2 ELISA Kit
 RSNL2 Recombinant
 RSNL2 Antibody
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Proteins Root Name Listing
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