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Carbonyl reductase

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NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prostaglandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S-nitrosoglutathione (By similarity).

Below are the list of possible Carbonyl reductase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Carbonyl reductase [NADPH] 1

 Carbonyl reductase [NADPH] 1 ELISA Kit
 Carbonyl reductase [NADPH] 1 Recombinant
 Carbonyl reductase [NADPH] 1 Antibody
Also known as Carbonyl reductase [NADPH] 1 (15-hydroxyprostaglandin dehydrogenase [NADP(+)]) (20-beta-hydroxysteroid dehydrogenase) (NADPH-dependent carbonyl reductase 1) (Prostaglandin 9-ketoreductase) (Prostaglandin-E(2) 9-reductase) (EC.
CBR1: NADPH-dependent reductase with broad substrate specificity. Catalyzes the reduction of a wide variety of carbonyl compounds including quinones, prosta
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glandins, menadione, plus various xenobiotics. Catalyzes the reduction of the antitumor anthracyclines doxorubicin and daunorubicin to the cardiotoxic compounds doxorubicinol and daunorubicinol. Can convert prostaglandin E2 to prostaglandin F2-alpha. Can bind glutathione, which explains its higher affinity for glutathione-conjugated substrates. Catalyzes the reduction of S-nitrosoglutathione. Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Protein type: EC 1.1.1.184; EC 1.1.1.189; EC 1.1.1.197; Lipid Metabolism - arachidonic acid; Oxidoreductase

Cellular Component: intracellular membrane-bound organelle; microvillus; nucleus; plasma membrane

Molecular Function: carbonyl reductase (NADPH) activity; oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor; protein binding

Biological Process: drug metabolic process; epithelial cell differentiation; ovulation from ovarian follicle; phylloquinone catabolic process; response to lipopolysaccharide; response to testosterone stimulus; steroid catabolic process; vitamin K metabolic process
 Cbr1 ELISA Kit
 Cbr1 Recombinant
 Cbr1 Antibody
 Cbr ELISA Kit
 Cbr Recombinant
 Cbr Antibody
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Carbonyl reductase [NADPH] 2

 Carbonyl reductase [NADPH] 2 ELISA Kit
 Carbonyl reductase [NADPH] 2 Recombinant
 Carbonyl reductase [NADPH] 2 Antibody
Also known as Carbonyl reductase [NADPH] 2 (Adipocyte protein P27) (AP27) (Lung carbonyl reductase) (LCR) (NADPH-dependent carbonyl reductase 2).
CBR2: May function in the pulmonary metabolism of endogenous carbonyl compounds, such as aliphatic aldehydes and ketones derived from lipid peroxidation, 3-ketosteroids and fatty aldehydes, as well as in xenobiotic metabolism. Belongs to the short-cha
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in dehydrogenases/reductases (SDR) family.

Protein type: EC 1.1.1.184

Cellular Component: mitochondrion

Molecular Function: carbonyl reductase (NADPH) activity; protein binding; protein self-association

Biological Process: NADH oxidation; protein tetramerization
 Cbr2 ELISA Kit
 Cbr2 Recombinant
 Cbr2 Antibody
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Carbonyl reductase [NADPH] 3

 Carbonyl reductase [NADPH] 3 ELISA Kit
 Carbonyl reductase [NADPH] 3 Recombinant
 Carbonyl reductase [NADPH] 3 Antibody
Also known as Carbonyl reductase [NADPH] 3 (NADPH-dependent carbonyl reductase 3).
CBR3: Has low NADPH-dependent oxidoreductase activity towards 4-benzoylpyridine and menadione (in vitro). Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Protein type: EC 1.1.1.184; Lipid Metabolism - arachidonic acid; Oxidoreductase

Cellular Component: cytoplasm; cytosol; extrace
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llular space; nucleoplasm

Molecular Function: 3-keto sterol reductase activity; carbonyl reductase (NADPH) activity

Biological Process: cognition; phylloquinone catabolic process
 Cbr3 ELISA Kit
 Cbr3 Recombinant
 Cbr3 Antibody
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