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Caspase recruitment domain-containing protein

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Below are the list of possible Caspase recruitment domain-containing protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Caspase recruitment domain-containing protein 064R

 Caspase recruitment domain-containing protein 064R ELISA Kit
 Caspase recruitment domain-containing protein 064R Recombinant
 Caspase recruitment domain-containing protein 064R Antibody
 FV3-064R ELISA Kit
 FV3-064R Recombinant
 FV3-064R Antibody
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Caspase recruitment domain-containing protein 10

 Caspase recruitment domain-containing protein 10 ELISA Kit
 Caspase recruitment domain-containing protein 10 Recombinant
 Caspase recruitment domain-containing protein 10 Antibody
Also known as Caspase recruitment domain-containing protein 10 (Bcl10-interacting MAGUK protein 1) (Bimp1).
CARD10: a protein containing a caspase recruitment domain (CARD) that functions as an activator of BCL10 and NF-kappaB signaling. CARD is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in apoptosis signaling through highly specific protein-protein ho
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mophilic interactions. CARD proteins function as scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. The CARD domain of CARD14 associates specifically with the CARD domains of CARD10 and BCL10, a signaling protein that activates NF-kB through the IkappaB kinase complex in response to upstream stimuli. When expressed in cells, CARD14 activates NF-kappaB and induces the phosphorylation of BCL10. A subgroup of primary lymphomas of the central nervous system have higher levels of CARD14 expression.

Protein type: Adaptor/scaffold

Biological Process: activation of NF-kappaB-inducing kinase
 Card10 ELISA Kit
 Card10 Recombinant
 Card10 Antibody
 Bimp1 ELISA Kit
 Bimp1 Recombinant
 Bimp1 Antibody
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Caspase recruitment domain-containing protein 11

 Caspase recruitment domain-containing protein 11 ELISA Kit
 Caspase recruitment domain-containing protein 11 Recombinant
 Caspase recruitment domain-containing protein 11 Antibody
CARD11: a CARD (caspase recruitment domain) protein that belongs to the membrane-associated guanylate kinase (MAGUK) family. MAGUK proteins function as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. Contains an N-terminal CARD domain, a central coiled-coil domain, and a C-terminal region containing a PDZ, an SH3, and a GUK. Its CARD do
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main associates with the CARD domain of BCL10. BCL10 activates NF-kappaB through the IkappaB kinase complex in response to upstream stimuli. Apparently activates NF-kappaB and induce the phosphorylation of BCL10. Detected in adult peripheral blood leukocytes, thymus, spleen and liver. Also found in promyelocytic leukemia HL-60 cells, chronic myelogenous leukemia K562 cells, Burkitt's lymphoma Raji cells and colorectal adenocarcinoma SW480 cells.

Protein type: Adaptor/scaffold

Cellular Component: cytoplasm; immunological synapse; lipid raft; plasma membrane; T cell receptor complex

Molecular Function: CARD domain binding; protein binding

Biological Process: activation of NF-kappaB transcription factor; B cell differentiation; B cell proliferation; homeostasis of number of cells; immunoglobulin production; lymphocyte activation; positive regulation of B cell proliferation; positive regulation of cytokine production; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of interleukin-2 biosynthetic process; positive regulation of T cell activation; positive regulation of T cell proliferation; regulation of B cell differentiation; regulation of immune response; regulation of T cell differentiation; signal transduction; T cell activation; T cell costimulation; thymic T cell selection
 Card11 ELISA Kit
 Card11 Recombinant
 Card11 Antibody
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Caspase recruitment domain-containing protein 14

 Caspase recruitment domain-containing protein 14 ELISA Kit
 Caspase recruitment domain-containing protein 14 Recombinant
 Caspase recruitment domain-containing protein 14 Antibody
Also known as Caspase recruitment domain-containing protein 14 (Bcl10-interacting MAGUK protein 2) (Bimp2).
CARD14: a protein containing a caspase recruitment domain (CARD) that functions as an activator of BCL10 and NF-kappaB signaling. CARD is a protein module that consists of 6 or 7 antiparallel alpha helices. It participates in signaling through highly specific protein-protein homophilic i
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nteractions. CARD proteins function as scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. The CARD domain of CARD14 associates specifically with the CARD domains of CARD10 and BCL10, a signaling protein that activates NF-kB through the IkappaB kinase complex in response to upstream stimuli. When expressed in cells, CARD14 activates NF-kappaB and induces the phosphorylation of BCL10. A subgroup of primary lymphomas of the central nervous system have higher levels of CARD14 expression.

Protein type: Adaptor/scaffold

Cellular Component: cytoplasm

Molecular Function: CARD domain binding

Biological Process: activation of NF-kappaB transcription factor; negative regulation of apoptosis; positive regulation of protein amino acid phosphorylation; tumor necrosis factor-mediated signaling pathway
 Card14 ELISA Kit
 Card14 Recombinant
 Card14 Antibody
 Bimp2 ELISA Kit
 Bimp2 Recombinant
 Bimp2 Antibody
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Caspase recruitment domain-containing protein 16

 Caspase recruitment domain-containing protein 16 ELISA Kit
 Caspase recruitment domain-containing protein 16 Recombinant
 Caspase recruitment domain-containing protein 16 Antibody
Also known as Caspase recruitment domain-containing protein 16 (Caspase recruitment domain-only protein 1) (CARD-only protein 1) (Caspase-1 inhibitor COP) (Pseudo interleukin-1 beta converting enzyme) (Pseudo-ICE) (Pseudo-IL1B-converting enzyme).
CARD16: Caspase inhibitor. Acts as a regulator of procaspase- 1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-interleukin-1 beta (IL1B) and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. Also induces NF-kappa-B activation during the pro- inflammatory cytokine respo
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nse. Also able to inhibit CASP1- mediated neuronal cell death, TNF-alpha, hypoxia-, UV-, and staurosporine-mediated cell death but not ER stress-mediated cell death. Acts by preventing activation of caspases CASP1 and CASP4, possibly by preventing the interaction between CASP1 and RIPK2. Down-regulated in patients suffering of Huntington disease. Homooligomer. Interacts with CASP1, CASP4, CARD8 and RIPK2. 2 isoforms of the human protein are produced by alternative splicing

Chromosomal Location of Human Ortholog: 11q22
 CARD16 ELISA Kit
 CARD16 Recombinant
 CARD16 Antibody
 COP ELISA Kit
 COP Recombinant
 COP Antibody
 COP1 ELISA Kit
 COP1 Recombinant
 COP1 Antibody
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Caspase recruitment domain-containing protein 17

 Caspase recruitment domain-containing protein 17 ELISA Kit
 Caspase recruitment domain-containing protein 17 Recombinant
 Caspase recruitment domain-containing protein 17 Antibody
Also known as Caspase recruitment domain-containing protein 17 (Caspase-1 inhibitor INCA) (Inhibitory caspase recruitment domain protein).
CARD17: Regulator of procaspase-1/CASP1 activation implicated in the regulation of the proteolytic maturation of pro-IL-1beta/IL1B and its release during inflammation. Inhibits the release of IL1B in response to LPS in monocytes. However, unlike CASP1, do no
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t induce NF-kappa-B activation.

Chromosomal Location of Human Ortholog: 11q22.3
 CARD17 ELISA Kit
 CARD17 Recombinant
 CARD17 Antibody
 INCA ELISA Kit
 INCA Recombinant
 INCA Antibody
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Caspase recruitment domain-containing protein 18

 Caspase recruitment domain-containing protein 18 ELISA Kit
 Caspase recruitment domain-containing protein 18 Recombinant
 Caspase recruitment domain-containing protein 18 Antibody
Also known as Caspase recruitment domain-containing protein 18 (Caspase-1 inhibitor Iceberg).
Inhibits generation of IL-1-beta by interacting with caspase-1 and preventing its association with RIP2. Down-regulates the release of IL1B.
 CARD18 ELISA Kit
 CARD18 Recombinant
 CARD18 Antibody
 ICEBERG ELISA Kit
 ICEBERG Recombinant
 ICEBERG Antibody
 UNQ5804/PRO19611 ELISA Kit
 UNQ5804/PRO19611 Recombinant
 UNQ5804/PRO19611 Antibody
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Caspase recruitment domain-containing protein 19

 Caspase recruitment domain-containing protein 19 ELISA Kit
 Caspase recruitment domain-containing protein 19 Recombinant
 Caspase recruitment domain-containing protein 19 Antibody
Also known as Caspase recruitment domain-containing protein 19 (Bcl10-interacting CARD protein) (BinCARD).
Plays a role in inhibiting the effects of BCL10-induced activation of NF-kappa-B. May inhibit the phosphorylation of BCL10 in a CARD-dependent manner.
 CARD19 ELISA Kit
 CARD19 Recombinant
 CARD19 Antibody
 C9orf89 ELISA Kit
 C9orf89 Recombinant
 C9orf89 Antibody
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Caspase recruitment domain-containing protein 6

 Caspase recruitment domain-containing protein 6 ELISA Kit
 Caspase recruitment domain-containing protein 6 Recombinant
 Caspase recruitment domain-containing protein 6 Antibody
CARD6: May be involved in apoptosis.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 5p13.1
 CARD6 ELISA Kit
 CARD6 Recombinant
 CARD6 Antibody
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Caspase recruitment domain-containing protein 8

 Caspase recruitment domain-containing protein 8 ELISA Kit
 Caspase recruitment domain-containing protein 8 Recombinant
 Caspase recruitment domain-containing protein 8 Antibody
Inhibits NF-kappa-B activation. May participate in a regulatory mechanism that coordinates cellular responses controlled by NF-kappa-B transcription factor. May be a component of the inflammasome, a protein complex which also includes PYCARD, NALP2 and CASP1 and whose function would be the activation of proinflammatory caspases ().
 CARD8 ELISA Kit
 CARD8 Recombinant
 CARD8 Antibody
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Caspase recruitment domain-containing protein 9

 Caspase recruitment domain-containing protein 9 ELISA Kit
 Caspase recruitment domain-containing protein 9 Recombinant
 Caspase recruitment domain-containing protein 9 Antibody
CARD9: Activates NF-kappa-B via BCL10. Defects in CARD9 are the cause of familial candidiasis type 2 (CANDF2). Chronic mucocutaneous candidiasis is characterized by impaired clearance of fungal infections and results in colonization and infections of the mucosa or skin, predominantly with Candida albicans. CANDF2 is an autosomal recessive chronic mucocutaneous candidiasis. 3 isoforms of the human
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protein are produced by alternative splicing.

Protein type: Adaptor/scaffold

Cellular Component: cytoplasm

Molecular Function: CARD domain binding; protein binding; protein domain specific binding; protein homodimerization activity

Biological Process: activation of NF-kappaB transcription factor; defense response to Gram-positive bacterium; defense response to virus; I-kappaB kinase/NF-kappaB cascade; positive regulation of innate immune response; positive regulation of interleukin-6 production; positive regulation of JNK cascade; positive regulation of stress-activated MAPK cascade; positive regulation of tumor necrosis factor production; regulation of interleukin-2 biosynthetic process; regulation of interleukin-6 biosynthetic process; regulation of tumor necrosis factor biosynthetic process; response to drug; response to exogenous dsRNA; response to fungus; response to muramyl dipeptide; response to peptidoglycan
 Card9 ELISA Kit
 Card9 Recombinant
 Card9 Antibody
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Proteins Root Name Listing
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