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D(4) dopamine receptor

Dopamine receptor responsible for neuronal signaling in the mesolimbic system of the brain, an area of the brain that regulates emotion and complex behavior. Its activity is mediated by G proteins which inhibit adenylyl cyclase. Modulates the circadian rhythm of contrast sensitivity by regulating the rhythmic expression of NPAS2 in the retinal ganglion cells (By similarity).

Below are the list of possible D(4) dopamine receptor products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.

D(4) dopamine receptor

 D(4) dopamine receptor ELISA Kit
 D(4) dopamine receptor Recombinant
 D(4) dopamine receptor Antibody
Also known as D(4) dopamine receptor (D(2C) dopamine receptor) (Dopamine D4 receptor).
DRD4: Dopamine receptor responsible for neuronal signaling in the mesolimbic system of the brain, an area of the brain that regulates emotion and complex behavior. Its activity is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family.

Protein type: GP
CR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

Chromosomal Location of Human Ortholog: 11p15.5

Cellular Component: integral to plasma membrane; membrane; plasma membrane

Molecular Function: dopamine binding; dopamine D1 receptor-like receptor activity; dopamine D2 receptor-like receptor activity; dopamine receptor activity; drug binding; identical protein binding; protein binding; SH3 domain binding

Biological Process: activation of MAPK activity; adult locomotory behavior; arachidonic acid secretion; behavioral response to cocaine; behavioral response to ethanol; cellular calcium ion homeostasis; dopamine metabolic process; dopamine receptor signaling pathway; dopamine receptor, adenylate cyclase inhibiting pathway; fear response; negative regulation of adenylate cyclase activity; negative regulation of cAMP biosynthetic process; negative regulation of protein secretion; positive regulation of dopamine uptake; positive regulation of kinase activity; positive regulation of sodium:hydrogen antiporter activity; regulation of circadian rhythm; regulation of dopamine metabolic process; regulation of inhibitory postsynaptic membrane potential; response to amphetamine; synaptic transmission, dopaminergic

Disease: Attention Deficit-hyperactivity Disorder; Novelty Seeking Personality Trait
 DRD4 Recombinant
 DRD4 Antibody
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