Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource  rightarrow Protein Family  rightarrow Dapper  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Proopiomelanocortin (POMC) Antibody
 • Tissue Factor (TF) ELISA Kit
 • RAB6-interacting golgin (Gorab) Recombinant Protein
 • ITLN1 Antibody
 • CD2 Antibody
 • CCL-25 Antibody
 • CYP4F3 siRNA
 • Chorionic Gonadotropin c3 Antibody
 • RREB1 Antibody
 • Semaphorin 3C (SEMA3C) ELISA Kit
 • Alternative Macrophage Activation-Associated Cc Chemokine 1 ... ELISA Kit
 • FABP Antibody
 • LGP2 (DHX58) Antibody
 • platelet factor 4 (PF4) ELISA Kit
 downarrow more ...
separator

Dapper

separator
Involved in regulation of intracellular signaling pathways during development. Specifically thought to play a role in canonical and/or non-canonical Wnt signaling pathways through interaction with DSH (Dishevelled) family proteins. Binds to dvl2 and regulates the degradation of ctnnb1/beta-catenin, thereby modulating the transcriptional activation of target genes of the Wnt signaling pathway. May also bind to and directly stimulate the activity of tcf7l1 (By similarity).

Below are the list of possible Dapper products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Dapper 1

 Dapper 1 ELISA Kit
 Dapper 1 Recombinant
 Dapper 1 Antibody
Involved in regulation of intracellular signaling pathways during development. Specifically thought to play a role in canonical and/or non-canonical Wnt signaling pathways through interaction with DSH (Dishevelled) family proteins. Binds to dvl2 and regulates the degradation of ctnnb1/beta-catenin, thereby modulating the transcriptional activation of target genes of the Wnt signaling pathway. May
>>>
also bind to and directly stimulate the activity of tcf7l1 ().
 dact1 ELISA Kit
 dact1 Recombinant
 dact1 Antibody
 TEgg062l20.1 ELISA Kit
 TEgg062l20.1 Recombinant
 TEgg062l20.1 Antibody
Table BarTOPTable Bar
 

Dapper 1-A

 Dapper 1-A ELISA Kit
 Dapper 1-A Recombinant
 Dapper 1-A Antibody
Also known as Dapper 1-A (Dapper1b) (XDpr1b) (Functional regulator of dsh in ontogenesis) (Frodo).
Involved in regulation of intracellular signaling pathways during development. Specifically thought to play a role in canonical and/or non-canonical Wnt signaling pathways through interaction with DSH (Dishevelled) family proteins. Binds to dvl2/dsh and impedes the degradation of beta-catenin (ctn
>>>
nb1-A and possibly ctnnb1-B), thereby enhancing the transcriptional activation of target genes of the Wnt signaling pathway. Also promotes catenin delta/ctnnd1 stability which in turn promotes zbtb33/kaiso sequestration and thus is involved in the regulation of zbtb33/kaiso-mediated transcriptional repression. May also bind to and directly stimulate the transcriptional activity of tcf7l1-A. Required for eye development and neural patterning.
 dact1-a ELISA Kit
 dact1-a Recombinant
 dact1-a Antibody
Table BarTOPTable Bar
 

Dapper 1-B

 Dapper 1-B ELISA Kit
 Dapper 1-B Recombinant
 Dapper 1-B Antibody
Also known as Dapper 1-B (xDpr) (Dapper1a) (XDpr1a).
Involved in regulation of intracellular signaling pathways during development. Specifically thought to play a role in canonical and/or non-canonical Wnt signaling pathways through interaction with DSH (Dishevelled) family proteins. Binds to dvl2 to regulate the degradation of beta-catenin (ctnnb1-A and possibly ctnnb1-B), thereby modulating t
>>>
he transcriptional activation of target genes of the Wnt signaling pathway. Seems to promote beta-catenin degradation if not phosphorylated and to block beta-catenin degradation if phosphorylated by CaMK1D. Involved in regulation of catenin delta/ctnnd1 protein level. May also bind to and directly stimulate the activity of tcf7l1-A. Also regulates the activation by dvl2 of jnk, a component of ctnnb1/beta-catenin-independent frizzled signaling. Required for notochord and head formation.
 dact1-b ELISA Kit
 dact1-b Recombinant
 dact1-b Antibody
Table BarTOPTable Bar
 

Dapper homolog 1

 Dapper homolog 1 ELISA Kit
 Dapper homolog 1 Recombinant
 Dapper homolog 1 Antibody
Also known as Dapper homolog 1 (Dapper antagonist of catenin 1) (Frodo homolog) (MDpr1) (Thymus-expressed novel gene 3 protein).
DACT1: Positively regulates DVL2-mediated signaling pathways during development. Binds to DVL2 and impedes the degradation of CTNNB1/beta-catenin, thereby enhancing the transcriptional activation of target genes of the Wnt signaling pathway. Interacts with DVL1 and DV
>>>
L2. Belongs to the dapper family.

Protein type: Adaptor/scaffold

Cellular Component: beta-catenin destruction complex; cytoplasm; nucleoplasm; nucleus

Molecular Function: beta-catenin binding; histone deacetylase binding; protein binding; protein kinase A binding; protein kinase C binding

Biological Process: dendrite morphogenesis; embryonic hindgut morphogenesis; embryonic morphogenesis; gastrulation with mouth forming second; negative regulation of JNK cascade; negative regulation of protein binding; negative regulation of transcription from RNA polymerase II promoter; negative regulation of Wnt receptor signaling pathway; neural tube development; positive regulation of fat cell differentiation; positive regulation of protein binding; positive regulation of protein catabolic process; positive regulation of Wnt receptor signaling pathway; regulation of protein stability; synapse organization and biogenesis; Wnt receptor signaling pathway through beta-catenin
 Dact1 ELISA Kit
 Dact1 Recombinant
 Dact1 Antibody
 Thyex3 ELISA Kit
 Thyex3 Recombinant
 Thyex3 Antibody
Table BarTOPTable Bar
 

Dapper homolog 2

 Dapper homolog 2 ELISA Kit
 Dapper homolog 2 Recombinant
 Dapper homolog 2 Antibody
Also known as Dapper homolog 2 (Dapper antagonist of catenin 2).
DACT2: Involved in regulation of intracellular signaling pathways during development. Negatively regulates the Nodal signaling pathway, possibly by promoting the lysosomal degradation of Nodal receptors, such as TGFBR1. May be involved in control of the morphogenetic behavior of kidney ureteric bud cells by keeping cells epithelial and restraining their mesenchymal character. May play an inhibitory role in the re-epithelialization of skin wounds by attenuating TGF-beta signaling. Belongs to the dapper family. 4 isoforms of the
>>>
human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 6q27

Cellular Component: cytoplasm

Molecular Function: beta-catenin binding; protein kinase A binding; protein kinase C binding; transcription factor binding

Biological Process: negative regulation of cell adhesion; regulation of Wnt receptor signaling pathway; skin development
 DACT2 ELISA Kit
 DACT2 Recombinant
 DACT2 Antibody
 C6orf116 ELISA Kit
 C6orf116 Recombinant
 C6orf116 Antibody
 PP13671 ELISA Kit
 PP13671 Recombinant
 PP13671 Antibody
Table BarTOPTable Bar
 

Dapper homolog 3

 Dapper homolog 3 ELISA Kit
 Dapper homolog 3 Recombinant
 Dapper homolog 3 Antibody
Also known as Dapper homolog 3 (Antagonist of beta-catenin Dapper homolog 3) (Arginine-rich region 1 protein) (Dapper antagonist of catenin 3).
DACT3: May be involved in regulation of intracellular signaling pathways during development. Specifically thought to play a role in canonical and/or non-canonical Wnt signaling pathways through interaction with DSH (Dishevelled) family proteins. Belongs
>>>
to the dapper family.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 19q13.32

Cellular Component: cytoplasm

Molecular Function: beta-catenin binding; protein kinase A binding; protein kinase C binding

Biological Process: negative regulation of cell growth; negative regulation of Wnt receptor signaling pathway
 DACT3 ELISA Kit
 DACT3 Recombinant
 DACT3 Antibody
 RRR1 ELISA Kit
 RRR1 Recombinant
 RRR1 Antibody
Table BarTOPTable Bar
Proteins Root Name Listing
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions