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DDK kinase regulatory

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Regulatory subunit of the CDC7-DBF4 kinase, also called DBF4-dependent kinase (DDK), which is involved in cell cycle regulation of premitotic and premeiotic chromosome replication and in chromosome segregation. DDK plays an essential role in initiating DNA replication at replication origins by phosphorylating the MCM2 and MCM4 subunits of the MCM2-7 helicase complex. DBF4 recruits the catalytic subunit CDC7 to MCM2 and to origins of replication. DDK has also postreplicative functions in meiosis. DDK phosphorylates the meiosis-specific double-strand break protein MER2 for initiation of meiotic recombination. Interacts with CDC5 during meiosis to promote double-strand breaks and monopolar spindle orientation. Inhibits CDC5 activity during mitosis through direct binding to its PBD.

Below are the list of possible DDK kinase regulatory products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

DDK kinase regulatory subunit DBF4

 DDK kinase regulatory subunit DBF4 ELISA Kit
 DDK kinase regulatory subunit DBF4 Recombinant
 DDK kinase regulatory subunit DBF4 Antibody
Also known as DDK kinase regulatory subunit DBF4 (Dumbbell forming protein 4).
Regulatory subunit of the CDC7-DBF4 kinase, also called DBF4-dependent kinase (DDK), which is involved in cell cycle regulation of premitotic and premeiotic chromosome replication and in chromosome segregation. DDK plays an essential role in initiating DNA replication at replication origins by phosphorylating the MCM2 and MCM4 subunits of the MCM2-7 helicase complex. DBF4 recruits the catalytic subunit CDC7 to MCM2 and to origins of replication. DDK has also postreplicative functions in meiosis. DDK phosphorylate
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s the meiosis-specific double-strand break protein MER2 for initiation of meiotic recombination. Interacts with CDC5 during meiosis to promote double-strand breaks and monopolar spindle orientation. Inhibits CDC5 activity during mitosis through direct binding to its PBD.
 DBF4 ELISA Kit
 DBF4 Recombinant
 DBF4 Antibody
 DNA52 ELISA Kit
 DNA52 Recombinant
 DNA52 Antibody
 YDR052C ELISA Kit
 YDR052C Recombinant
 YDR052C Antibody
 D4205 ELISA Kit
 D4205 Recombinant
 D4205 Antibody
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