| Deazaflavin-dependent nitroreductase ELISA Kit|
Deazaflavin-dependent nitroreductase Recombinant
Deazaflavin-dependent nitroreductase Antibody
|Also known as Deazaflavin-dependent nitroreductase (F420H(2)-dependent quinone reductase Ddn) (Fqr). |
Involved in a F420-dependent anti-oxidant mechanism that protects M.tuberculosis against oxidative stress and bactericidal agents. Catalyzes the F420H(2)-dependent two-electron reduction of quinones to dihydroquinones, thereby preventing the formation of cytotoxic semiquinones obtained by the on
e-electron reduction pathway. In vitro, catalyzes the reduction of both benzoquinone and naphthoquinone analogs; since menaquinone is the sole quinone electron carrier in the respiratory chain in M.tuberculosis, the physiological electron acceptor for Fqr-mediated F420H2 oxidation is therefore likely to be the endogenous menaquinone found in the membrane fraction of M.tuberculosis. Is able to use F420 species with two and five glutamate residues in its polyglutamate tail. Cannot use NADH or NADPH instead of F420H2 as the electron donor.
| ddn ELISA Kit|
| MT3651 ELISA Kit|