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Deazaflavin-dependent nitroreductase

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Involved in a F420-dependent anti-oxidant mechanism that protects M.tuberculosis against oxidative stress and bactericidal agents. Catalyzes the F420H(2)-dependent two-electron reduction of quinones to dihydroquinones, thereby preventing the formation of cytotoxic semiquinones obtained by the one-electron reduction pathway. In vitro, catalyzes the reduction of both benzoquinone and naphthoquinone analogs; since menaquinone is the sole quinone electron carrier in the respiratory chain in M.tuberculosis, the physiological electron acceptor for Fqr-mediated F420H(2) oxidation is therefore likely to be the endogenous menaquinone found in the membrane fraction of M.tuberculosis. Is able to use F420 species with two and five glutamate residues in its polyglutamate tail. Cannot use NADH or NADPH instead of F420H(2) as the electron donor.

Below are the list of possible Deazaflavin-dependent nitroreductase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Deazaflavin-dependent nitroreductase

 Deazaflavin-dependent nitroreductase ELISA Kit
 Deazaflavin-dependent nitroreductase Recombinant
 Deazaflavin-dependent nitroreductase Antibody
Also known as Deazaflavin-dependent nitroreductase (F420H(2)-dependent quinone reductase Ddn) (Fqr).
Involved in a F420-dependent anti-oxidant mechanism that protects M.tuberculosis against oxidative stress and bactericidal agents. Catalyzes the F420H(2)-dependent two-electron reduction of quinones to dihydroquinones, thereby preventing the formation of cytotoxic semiquinones obtained by the on
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e-electron reduction pathway. In vitro, catalyzes the reduction of both benzoquinone and naphthoquinone analogs; since menaquinone is the sole quinone electron carrier in the respiratory chain in M.tuberculosis, the physiological electron acceptor for Fqr-mediated F420H2 oxidation is therefore likely to be the endogenous menaquinone found in the membrane fraction of M.tuberculosis. Is able to use F420 species with two and five glutamate residues in its polyglutamate tail. Cannot use NADH or NADPH instead of F420H2 as the electron donor.
 ddn ELISA Kit
 ddn Recombinant
 ddn Antibody
 MT3651 ELISA Kit
 MT3651 Recombinant
 MT3651 Antibody
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