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Delta-type opioid receptor

G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine.

Below are the list of possible Delta-type opioid receptor products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.

Delta-type opioid receptor

 Delta-type opioid receptor ELISA Kit
 Delta-type opioid receptor Recombinant
 Delta-type opioid receptor Antibody
Also known as Delta-type opioid receptor (D-OR-1) (DOR-1).
DOR-1: delta opioid receptor, a G-protein coupled receptor. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Highly stereoselective. Receptor for enkephalins.

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR

romosomal Location of Human Ortholog: 1p36.1-p34.3

Cellular Component: integral to plasma membrane; intrinsic to plasma membrane; neuron projection; plasma membrane

Molecular Function: neuropeptide binding; opioid receptor activity; protein binding

Biological Process: activation of CREB transcription factor; G-protein coupled receptor protein signaling pathway; G-protein signaling, coupled to cyclic nucleotide second messenger; G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); immune response; negative regulation of protein oligomerization; neuropeptide signaling pathway; positive regulation of peptidyl-serine phosphorylation; protein import into nucleus, translocation; regulation of mitochondrial membrane potential; sensory perception of pain; synaptic transmission
 OPRD1 Recombinant
 OPRD1 Antibody
 OPRD Recombinant
 OPRD Antibody
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