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Dendritic cell-specific transmembrane protein

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Probable cell surface receptor that plays several roles in cellular fusion, cell differentiation, bone and immune homeostasis. Plays a role in TNFSF11-mediated osteoclastogenesis. Cooperates with OCSTAMP in modulating cell-cell fusion in both osteoclasts and foreign body giant cells (FBGCs). Participates in osteoclast bone resorption. Involved in inducing the expression of tartrate-resistant acid phosphatase in osteoclast precursors. Plays a role in haematopoietic stem cell differentiation of bone marrow cells toward the myeloid lineage. Inhibits the development of neutrophilic granulocytes. Plays also a role in the regulation of dendritic cell (DC) antigen presentation activity by controlling phagocytic activity. Involved in the maintenance of immune self-tolerance and avoidance of autoimmune reactions.

Below are the list of possible Dendritic cell-specific transmembrane protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Dendritic cell-specific transmembrane protein

 Dendritic cell-specific transmembrane protein ELISA Kit
 Dendritic cell-specific transmembrane protein Recombinant
 Dendritic cell-specific transmembrane protein Antibody
Also known as Dendritic cell-specific transmembrane protein (DC-STAMP) (hDC-STAMP) (Dendrocyte-expressed seven transmembrane protein) (IL-four-induced protein) (FIND) (Transmembrane 7 superfamily member 4).
TM7SF4: Probable cell surface receptor that plays several roles in cellular fusion, cell differentiation, bone and immune homeostasis. Plays a role in TNFSF11-mediated osteoclastogenesis. Co
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operates with OCSTAMP in modulating cell-cell fusion in both osteoclasts and foreign body giant cells (FBGCs). Participates in osteoclast bone resorption. Involved in inducing the expression of tartrate-resistant acid phosphatase in osteoclast precursors. Plays a role in haematopoietic stem cell differentiation of bone marrow cells toward the myeloid lineage. Inhibits the development of neutrophilic granulocytes. Plays also a role in the regulation of dendritic cell (DC) antigen presentation activity by controlling phagocytic activity. Involved in the maintenance of immune self-tolerance and avoidance of autoimmune reactions.

Protein type: Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 8q23

Cellular Component: cell surface; endoplasmic reticulum membrane; endosome membrane; integral to endoplasmic reticulum membrane; integral to plasma membrane

Molecular Function: protein binding

Biological Process: myeloid dendritic cell differentiation; negative regulation of cell growth; osteoclast differentiation; positive regulation of bone resorption; positive regulation of monocyte differentiation
 DCSTAMP ELISA Kit
 DCSTAMP Recombinant
 DCSTAMP Antibody
 TM7SF4 ELISA Kit
 TM7SF4 Recombinant
 TM7SF4 Antibody
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