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Desmoglein

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Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.

Below are the list of possible Desmoglein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Desmoglein-1

 Desmoglein-1 ELISA Kit
 Desmoglein-1 Recombinant
 Desmoglein-1 Antibody
Also known as Desmoglein-1 (Cadherin family member 4) (Desmosomal glycoprotein 1) (DG1) (DGI) (Pemphigus foliaceus antigen).
DSG1: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Defects in DSG1 are the cause of palmoplantar keratoderma striate type 1 (SPPK1); also known as keratosis palmopla
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ntaris striata I. SPPK1 is a dermatoligical disorder characterized by thickening of the skin on the palms and soles, and longitudinal hyperkeratotic lesions on the palms, running the length of each finger.

Protein type: Cell adhesion; Membrane protein, integral

Chromosomal Location of Human Ortholog: 18q12.1

Cellular Component: cytosol; extracellular matrix; intercellular junction; internal side of plasma membrane; plasma membrane

Molecular Function: gamma-catenin binding; protein binding

Biological Process: protein stabilization

Disease: Erythroderma, Congenital, With Palmoplantar Keratoderma, Hypotrichosis, And Hyper-ige; Palmoplantar Keratoderma I, Striate, Focal, Or Diffuse
 DSG1 ELISA Kit
 DSG1 Recombinant
 DSG1 Antibody
 CDHF4 ELISA Kit
 CDHF4 Recombinant
 CDHF4 Antibody
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Desmoglein-1-alpha

 Desmoglein-1-alpha ELISA Kit
 Desmoglein-1-alpha Recombinant
 Desmoglein-1-alpha Antibody
Also known as Desmoglein-1-alpha (Desmoglein-1) (Dsg1-alpha) (DG1) (DGI) (Desmosomal glycoprotein I).
DSG1: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Defects in DSG1 are the cause of palmoplantar keratoderma striate type 1 (SPPK1); also known as keratosis palmoplantaris striata I. SPPK1
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is a dermatoligical disorder characterized by thickening of the skin on the palms and soles, and longitudinal hyperkeratotic lesions on the palms, running the length of each finger.

Protein type: Cell adhesion; Membrane protein, integral

Cellular Component: apical plasma membrane; desmosome; extracellular matrix; intercellular junction; internal side of plasma membrane; lateral plasma membrane; plasma membrane

Molecular Function: gamma-catenin binding; protein binding
 Dsg1a ELISA Kit
 Dsg1a Recombinant
 Dsg1a Antibody
 Dsg1 ELISA Kit
 Dsg1 Recombinant
 Dsg1 Antibody
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Desmoglein-1-beta

 Desmoglein-1-beta ELISA Kit
 Desmoglein-1-beta Recombinant
 Desmoglein-1-beta Antibody
Also known as Desmoglein-1-beta (Dsg1-beta) (Desmoglein-5).
Dsg1b: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion.

Protein type: Cell adhesion; Membrane protein, integral

Cellular Component: apical plasma membrane; desmosome; extracellular matrix; intercellular junction; interna
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l side of plasma membrane; lateral plasma membrane

Molecular Function: gamma-catenin binding
 Dsg1b ELISA Kit
 Dsg1b Recombinant
 Dsg1b Antibody
 Dsg5 ELISA Kit
 Dsg5 Recombinant
 Dsg5 Antibody
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Desmoglein-1-gamma

 Desmoglein-1-gamma ELISA Kit
 Desmoglein-1-gamma Recombinant
 Desmoglein-1-gamma Antibody
Also known as Desmoglein-1-gamma (Dsg1-gamma) (Desmoglein-6).
This gene encodes a member of the cadherin family of proteins that forms an integral transmembrane component of desmosomes, the multiprotein complexes involved in cell adhesion, organization of the cytoskeleton, cell sorting and cell signaling. The encoded preproprotein undergoes proteolytic processing to generate a mature, functiona
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l protein. This gene is located in a cluster of desmosomal cadherin genes on chromosome 18. [provided by RefSeq, Jan 2016]
 Dsg1c ELISA Kit
 Dsg1c Recombinant
 Dsg1c Antibody
 Dsg6 ELISA Kit
 Dsg6 Recombinant
 Dsg6 Antibody
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Desmoglein-2

 Desmoglein-2 ELISA Kit
 Desmoglein-2 Recombinant
 Desmoglein-2 Antibody
DSG2: Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Defects in DSG2 are the cause of familial arrhythmogenic right ventricular dysplasia type 10 (ARVD10); also known as arrhythmogenic right ventricular cardiomyopathy 10 (ARVC10). ARVD is an autosomal dominant disease characterized by partial d
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egeneration of the myocardium of the right ventricle, electrical instability, and sudden death. It is clinically defined by electrocardiographic and angiographic criteria; pathologic findings, replacement of ventricular myocardium with fatty and fibrous elements, preferentially involve the right ventricular free wall. Genetic variations in DSG2 are the cause of susceptibility to cardiomyopathy dilated type 1BB (CMD1BB). A disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.

Protein type: Calcium-binding; Cell adhesion; Membrane protein, integral

Cellular Component: apical plasma membrane; cell surface; desmosome; lateral plasma membrane; plasma membrane

Molecular Function: cell adhesion molecule binding

Biological Process: cell adhesion; homophilic cell adhesion
 Dsg2 ELISA Kit
 Dsg2 Recombinant
 Dsg2 Antibody
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Desmoglein-3

 Desmoglein-3 ELISA Kit
 Desmoglein-3 Recombinant
 Desmoglein-3 Antibody
Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion ().
 DSG3 ELISA Kit
 DSG3 Recombinant
 DSG3 Antibody
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Desmoglein-4

 Desmoglein-4 ELISA Kit
 Desmoglein-4 Recombinant
 Desmoglein-4 Antibody
cell adhesion molecule; involved in providing mechanical integrity and stability to epithelial cells [RGD, Feb 2006]
 Dsg4 ELISA Kit
 Dsg4 Recombinant
 Dsg4 Antibody
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