Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource  rightarrow Protein Family  rightarrow Dickkopf-related protein  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • UPF0317 protein RL2444 (RL2444) Recombinant Protein
 • Intercellular Adhesion Molecule 2 (ICAM-2) ELISA Kit
 • Nitric oxide synthase (Nos3) ELISA Kit
 • Activated Protein C (APC) ELISA Kit
 • Oxidized low-density lipoprotein receptor 1 (OLR1) Recombinant Protein
 • Fanconi anemia, complementation group C Antibody
 • Cortisol ELISA Kit
 • Chaperone protein htpG (htpG) Recombinant Protein
 • 5-Phosphoribosyl 1-Pyrophosphate (PRPP) ELISA Kit
 • RAB11FIP5 Antibody
 • Collagen Type I (COL1A1) Native Protein
 • CKB-Brain Creatine Kinase Antibody
 • B2M Antibody
 • Cerebellin 1 (CBLN1) ELISA Kit
 downarrow more ...
separator

Dickkopf-related protein

separator
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.

Below are the list of possible Dickkopf-related protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Dickkopf-related protein 1

 Dickkopf-related protein 1 ELISA Kit
 Dickkopf-related protein 1 Recombinant
 Dickkopf-related protein 1 Antibody
Also known as Dickkopf-related protein 1 (Dickkopf-1) (Dkk-1) (hDkk-1) (SK).
DKK1: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero- po
>>>
sterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. Interacts with LRP6. Interacts (via the C-termianl Cys- rich domain) with LRP5 (via beta-propeller regions 3 and 4); the interaction, enhanced by MESD and or KREMEN, antagonizes Wnt- mediated signaling. Placenta. Belongs to the dickkopf family.

Protein type: Inhibitor; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 10q11.2

Cellular Component: early endosome membrane; extracellular region; extracellular space; plasma membrane

Molecular Function: growth factor activity; low-density lipoprotein receptor binding; protein binding; receptor antagonist activity; signal transducer activity

Biological Process: negative regulation of mesodermal cell fate specification; negative regulation of peptidyl-serine phosphorylation; negative regulation of protein binding; negative regulation of transcription from RNA polymerase II promoter; negative regulation of Wnt receptor signaling pathway; regulation of endodermal cell fate specification; regulation of receptor internalization
 DKK1 ELISA Kit
 DKK1 Recombinant
 DKK1 Antibody
 UNQ492/PRO1008 ELISA Kit
 UNQ492/PRO1008 Recombinant
 UNQ492/PRO1008 Antibody
Table BarTOPTable Bar
 

Dickkopf-related protein 2

 Dickkopf-related protein 2 ELISA Kit
 Dickkopf-related protein 2 Recombinant
 Dickkopf-related protein 2 Antibody
Also known as Dickkopf-related protein 2 (Dickkopf-2) (Dkk-2) (hDkk-2).
DKK2: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero- posteri
>>>
or axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. Interacts with LRP5 and LRP6. Expressed in heart, brain, skeletal muscle and lung. Belongs to the dickkopf family.

Protein type: Inhibitor; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 4q25

Cellular Component: extracellular space
 DKK2 ELISA Kit
 DKK2 Recombinant
 DKK2 Antibody
 UNQ682/PRO1316 ELISA Kit
 UNQ682/PRO1316 Recombinant
 UNQ682/PRO1316 Antibody
Table BarTOPTable Bar
 

Dickkopf-related protein 3

 Dickkopf-related protein 3 ELISA Kit
 Dickkopf-related protein 3 Recombinant
 Dickkopf-related protein 3 Antibody
Also known as Dickkopf-related protein 3 (Dickkopf-3) (Dkk-3) (hDkk-3).
DKK3: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero- posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. Belongs to the dickkopf fami
>>>
ly.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 11p15.2

Biological Process: adrenal gland development; anatomical structure morphogenesis; negative regulation of aldosterone biosynthetic process; negative regulation of transcription, DNA-dependent
 DKK3 ELISA Kit
 DKK3 Recombinant
 DKK3 Antibody
 REIC ELISA Kit
 REIC Recombinant
 REIC Antibody
 UNQ258/PRO295 ELISA Kit
 UNQ258/PRO295 Recombinant
 UNQ258/PRO295 Antibody
Table BarTOPTable Bar
 

Dickkopf-related protein 4

 Dickkopf-related protein 4 ELISA Kit
 Dickkopf-related protein 4 Recombinant
 Dickkopf-related protein 4 Antibody
Also known as Dickkopf-related protein 4 (Dickkopf-4) (Dkk-4).
DKK4: Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero- posterior axial
>>>
patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. Belongs to the dickkopf family.

Protein type: Inhibitor; Secreted; Secreted, signal peptide

Biological Process: Wnt receptor signaling pathway
 Dkk4 ELISA Kit
 Dkk4 Recombinant
 Dkk4 Antibody
Table BarTOPTable Bar
Proteins Root Name Listing
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions