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Dimethylglycine oxidase ELISA Kit Dimethylglycine oxidase Recombinant Dimethylglycine oxidase Antibody | Also known as Dimethylglycine oxidase (DMGO). Catalyzes the oxidative demethylation of N,N-dimethylglycine to yield sarcosine, formaldehyde and hydrogen peroxide. The oxidation of dimethylglycine is coupled to the synthesis of 5,10-methylenetetrahydrofolate through an unusual substrate channeling mechanism. This channeling occurs by nonbiased diffusion of the iminium intermediate through a larg >>> e solvent cavity connecting active site 1 (N-terminus) and active site 2 (C-terminus). The synthesis of 5,10-methylenetetrahydrofolate (at active site 2) prevents the accumulation of formaldehyde, formed by hydrolysis of the iminium intermediate product (at active site 1). Does not oxidize sarcosine. |
dmg ELISA Kit dmg Recombinant dmg Antibody |
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