Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
Fax 1.858.633.0166    Email 
menu1 Home Products Ordering Company Help menu7
   MyBioSource  rightarrow Protein Family  rightarrow DIS3-like exonuclease  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
Our Best Sellers moreseparator
 • ASK1 (MAP3K5) Antibody
 • IL-1sRI ELISA Kit
 • Albumin Antibody
 • GATA3 Peptide
 • Pancreatic alpha-amylase (AMY2A) Antibody
 • Glucokinase regulatory protein (GCKR) Recombinant Protein
 • Interleukin 6 Receptor, gp80, non-neutralizing Antibody
 • Neurotrophin 3 (NT3) ELISA Kit
 • BRP44 cDNA Clone
 • Placenta Growth Factor-2 (PLGF 2) Recombinant Protein
 • Proline-Rich AKT1 Substrate 1 (AKT1S1) ELISA Kit
 • MHCG (Major Histocompatibility Complex Class I G) CLIA Kit
 • CLDN15 Antibody
 downarrow more ...

DIS3-like exonuclease

Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events.

Below are the list of possible DIS3-like exonuclease products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.

DIS3-like exonuclease 1

 DIS3-like exonuclease 1 ELISA Kit
 DIS3-like exonuclease 1 Recombinant
 DIS3-like exonuclease 1 Antibody
Putative cytoplasm-specific catalytic component of the RNA exosome complex which has 3'->5' exoribonuclease activity and participates in a multitude of cellular RNA processing and degradation events.
 dis3l ELISA Kit
 dis3l Recombinant
 dis3l Antibody
Table BarTOPTable Bar

DIS3-like exonuclease 2

 DIS3-like exonuclease 2 ELISA Kit
 DIS3-like exonuclease 2 Recombinant
 DIS3-like exonuclease 2 Antibody
DIS3L2: Ribonuclease that plays a critical role in RNA metabolism. It is essential for correct mitosis, and negatively regulates cell proliferation. Defects in DIS3L2 are the cause of Perlman syndrome (PRLMNS). An autosomal recessive congenital overgrowth syndrome. Affected children are large at birth, are hypotonic, and show organomegaly, characteristic facial dysmorphisms (inverted V-shaped uppe
r lip, prominent forehead, deep-set eyes, broad and flat nasal bridge, and low-set ears), renal anomalies (nephromegaly and hydronephrosis), frequent neurodevelopmental delay, and high neonatal mortality. Perlman syndrome is associated with a high risk of Wilms tumor. Histologic examination of the kidneys in affected children shows frequent nephroblastomatosis, which is a precursor lesion for Wilms tumor. Belongs to the RNR ribonuclease family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.1.13.-; Ribonuclease; Tumor suppressor

Cellular Component: cytoplasm; nuclear exosome (RNase complex)

Molecular Function: 3'-5'-exoribonuclease activity; magnesium ion binding; poly(U) binding; ribonuclease activity

Biological Process: mitosis; mitotic sister chromatid separation; mRNA catabolic process; mRNA catabolic process, exonucleolytic; negative regulation of cell proliferation; rRNA catabolic process; rRNA processing; stem cell maintenance
 Dis3l2 ELISA Kit
 Dis3l2 Recombinant
 Dis3l2 Antibody
Table BarTOPTable Bar
Proteins Root Name Listing
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions