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Disintegrin mojastin

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Disintegrin mojastin-1: inhibits the three processes involved in platelet function (adhesion, activation and aggregation). It inhibits platelet adhesion to fibronectin with an IC(50) of 58.6 nM. It inhibits ATP release from platelet induced by ADP with an IC(50) of 19.5 nM on platelet-rich plasma, probably by binding to ADP receptors (P2RY1 and P2RY12). Finally, it inhibits ADP-induced platelet aggregation with IC(50) of 44.7 nM on platelet-rich plasma and 19.3 nM on whole blood, probably by binding to alpha-IIb/beta-3 (ITGA2B/ITGB3) .

Below are the list of possible Disintegrin mojastin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Disintegrin mojastin-2

 Disintegrin mojastin-2 ELISA Kit
 Disintegrin mojastin-2 Recombinant
 Disintegrin mojastin-2 Antibody
Disintegrin mojastin-1: inhibits the three processes involved in platelet function (adhesion, activation and aggregation). It inhibits platelet adhesion to fibronectin with an IC50 of 58.6 nM. It inhi
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bits ATP release from platelet induced by ADP with an IC50 of 19.5 nM on platelet-rich plasma, probably by binding to ADP receptors (P2RY1 and P2RY12). Finally, it inhibits ADP-induced platelet aggregation with IC50 of 44.7 nM on platelet-rich plasma and 19.3 nM on whole blood, probably by binding to alpha-IIb/beta-3 (ITGA2B/ITGB3) (PubMed:20598348).
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