| DNA-binding protein inhibitor ID-2 ELISA Kit|
DNA-binding protein inhibitor ID-2 Recombinant
DNA-binding protein inhibitor ID-2 Antibody
|Also known as DNA-binding protein inhibitor ID-2 (Class B basic helix-loop-helix protein 26) (bHLHb26) (Inhibitor of DNA binding 2) (Inhibitor of differentiation 2). |
ID2: ID (inhibitor of DNA binding) HLH proteins lack a basic DNA-binding domain but are able to form heterodimers with other HLH proteins, thereby inhibiting DNA binding. ID-2 may be an inhibitor of tissue-specific gene expression.
Heterodimer with other HLH proteins. Interacts with GATA4, IFI204 and NKX2-5. Interacts with NR0B2. Highly expressed in early fetal tissues, including those of the central nervous system.
Protein type: DNA-binding; Transcription, coactivator/corepressor
Chromosomal Location of Human Ortholog: 2p25
Cellular Component: centrosome; cytoplasm; cytosol; nucleoplasm; nucleus; protein complex
Molecular Function: protein binding
Biological Process: circadian regulation of gene expression; embryonic digestive tract morphogenesis; entrainment of circadian clock by photoperiod; locomotor rhythm; mammary gland epithelial cell proliferation; multicellular organismal development; negative regulation of neuron differentiation; negative regulation of transcription factor activity; negative regulation of transcription, DNA-dependent; neuron fate commitment; positive regulation of blood pressure; positive regulation of smooth muscle cell proliferation; positive regulation of transcription, DNA-dependent; regulation of circadian rhythm; regulation of lipid metabolic process
| ID2 ELISA Kit|
| BHLHB26 ELISA Kit|