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DNA-directed primase/polymerase protein

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DNA primase and DNA polymerase able to initiate de novo DNA synthesis using dNTPs. Shows a high capacity to tolerate DNA damage lesions such as 8oxoG and abasic sites in DNA. Involved in translesion synthesis via its primase activity by mediating uninterrupted fork progression after programmed or damage-induced fork arrest and by reinitiating DNA synthesis after dNTP depletion. Required for mitochondrial DNA (mtDNA) synthesis, suggesting it may be involved in DNA tolerance during the replication of mitochondrial DNA. Has non-overlapping function with POLH (By similarity).

Below are the list of possible DNA-directed primase/polymerase protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

DNA-directed primase/polymerase protein

 DNA-directed primase/polymerase protein ELISA Kit
 DNA-directed primase/polymerase protein Recombinant
 DNA-directed primase/polymerase protein Antibody
Also known as DNA-directed primase/polymerase protein (Coiled-coil domain-containing protein 111 homolog).
DNA primase and DNA polymerase able to initiate de novo DNA synthesis using dNTPs. Shows a high capacity to tolerate DNA damage lesions such as 8oxoG and abasic sites in DNA. Involved in translesion synthesis via its primase activity by mediating uninterrupted fork progression after programmed or damage-induced fork arrest and by reinitiating DNA synthesis after dNTP depletion. Required for mitochondrial DNA (mtDNA) synthesis, suggesting it may be involved in DNA tolerance during the r
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eplication of mitochondrial DNA. Has non-overlapping function with POLH ().
 primpol ELISA Kit
 primpol Recombinant
 primpol Antibody
 ccdc111 ELISA Kit
 ccdc111 Recombinant
 ccdc111 Antibody
 zgc:123274 ELISA Kit
 zgc:123274 Recombinant
 zgc:123274 Antibody
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