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DNA-repair protein

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Corrects defective DNA strand-break repair and sister chromatid exchange following treatment with ionizing radiation and alkylating agents (By similarity). Involved in DNA demethylation pathway by stimulating cytosine methylation (5-meC) excision, gap tailoring, and DNA ligation.

Below are the list of possible DNA-repair protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

DNA repair protein complementing XP-A cells

 DNA repair protein complementing XP-A cells ELISA Kit
 DNA repair protein complementing XP-A cells Recombinant
 DNA repair protein complementing XP-A cells Antibody
Also known as DNA repair protein complementing XP-A cells (Xeroderma pigmentosum group A-complementing protein).
XPA: Involved in DNA excision repair. Initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. Required for UV-induced CHEK1 phosphorylation and the recruitment of CEP164 to cyclobutane pyrimidine
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dimmers (CPD), sites of DNA damage after UV irradiation. Interacts with GPN1 and RPA1. Interacts (via N-terminus) with CEP164 upon UV irradiation. Interacts with HERC2. Expressed in various cell lines and in skin fibroblasts. Belongs to the XPA family.

Protein type: DNA repair, damage

Chromosomal Location of Human Ortholog: 9q22.3

Cellular Component: cytoplasm; DNA replication factor A complex; Golgi apparatus; intercellular bridge; nucleoplasm; nucleus

Molecular Function: damaged DNA binding; protein binding; protein domain specific binding; protein homodimerization activity

Biological Process: base-excision repair; nucleotide-excision repair, DNA damage recognition; nucleotide-excision repair, DNA duplex unwinding; nucleotide-excision repair, DNA incision; nucleotide-excision repair, DNA incision, 3'-to lesion; nucleotide-excision repair, DNA incision, 5'-to lesion; nucleotide-excision repair, preincision complex assembly; nucleotide-excision repair, preincision complex stabilization; transcription-coupled nucleotide-excision repair

Disease: Xeroderma Pigmentosum, Complementation Group A
 XPA ELISA Kit
 XPA Recombinant
 XPA Antibody
 XPAC ELISA Kit
 XPAC Recombinant
 XPAC Antibody
Table BarTOPTable Bar
 

DNA repair protein complementing XP-A cells homolog

 DNA repair protein complementing XP-A cells homolog ELISA Kit
 DNA repair protein complementing XP-A cells homolog Recombinant
 DNA repair protein complementing XP-A cells homolog Antibody
Also known as DNA repair protein complementing XP-A cells homolog (Xeroderma pigmentosum group A-complementing protein homolog).
Involved in DNA excision repair. Initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region ().
 XPA ELISA Kit
 XPA Recombinant
 XPA Antibody
 XPAC ELISA Kit
 XPAC Recombinant
 XPAC Antibody
Table BarTOPTable Bar
 

DNA repair protein complementing XP-C cells

 DNA repair protein complementing XP-C cells ELISA Kit
 DNA repair protein complementing XP-C cells Recombinant
 DNA repair protein complementing XP-C cells Antibody
Also known as DNA repair protein complementing XP-C cells (Xeroderma pigmentosum group C-complementing protein) (p125).
XPC: a probable nuclear protein involved in DNA excision repair. May play a part in DNA damage recognition and/or in altering chromatin structure to allow access by damage-processing enzymes. Defects in XPC are a cause of xeroderma pigmentosum complementation group C.

P
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rotein type: DNA repair, damage

Chromosomal Location of Human Ortholog: 3p25.1

Cellular Component: cytoplasm; nucleolus; nucleoplasm; nucleus; plasma membrane

Molecular Function: bubble DNA binding; damaged DNA binding; loop DNA binding; protein binding; single-stranded DNA binding

Biological Process: DNA repair; mismatch repair; nucleotide-excision repair; nucleotide-excision repair, DNA damage recognition; nucleotide-excision repair, DNA duplex unwinding; nucleotide-excision repair, preincision complex assembly; protein sumoylation

Disease: Xeroderma Pigmentosum, Complementation Group C
 XPC ELISA Kit
 XPC Recombinant
 XPC Antibody
 XPCC ELISA Kit
 XPCC Recombinant
 XPCC Antibody
Table BarTOPTable Bar
 

DNA repair protein complementing XP-C cells homolog

 DNA repair protein complementing XP-C cells homolog ELISA Kit
 DNA repair protein complementing XP-C cells homolog Recombinant
 DNA repair protein complementing XP-C cells homolog Antibody
Also known as DNA repair protein complementing XP-C cells homolog (Mutagen-sensitive 209 protein) (XPCDM) (Xeroderma pigmentosum group C-complementing protein homolog).
Involved in DNA excision repair. May play a part in DNA damage recognition and/or in altering chromatin structure to allow access by damage-processing enzymes ().
 Xpc ELISA Kit
 Xpc Recombinant
 Xpc Antibody
 mus210 ELISA Kit
 mus210 Recombinant
 mus210 Antibody
 Xpcc ELISA Kit
 Xpcc Recombinant
 Xpcc Antibody
 CG8153 ELISA Kit
 CG8153 Recombinant
 CG8153 Antibody
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DNA repair protein complementing XP-G cells

 DNA repair protein complementing XP-G cells ELISA Kit
 DNA repair protein complementing XP-G cells Recombinant
 DNA repair protein complementing XP-G cells Antibody
Also known as DNA repair protein complementing XP-G cells (DNA excision repair protein ERCC-5) (Xeroderma pigmentosum group G-complementing protein).
XPG: Single-stranded structure-specific DNA endonuclease involved in DNA excision repair. Makes the 3'incision in DNA nucleotide excision repair (NER). Acts as a cofactor for a DNA glycosylase that removes oxidized pyrimidines from DNA. May also be involved in transcription-coupled repair of this kind of damage, in transcription by RNA polymerase II, and perhaps in other processes too. Defects in ERCC5 are the cause of xeroderma pigmentosum co
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mplementation group G (XP-G); also known as xeroderma pigmentosum VII (XP7). Xeroderma pigmentosum is an autosomal recessive pigmentary skin disorder characterized by solar hypersensitivity of the skin, high predisposition for developing cancers on areas exposed to sunlight and, in some cases, neurological abnormalities. Some XP-G patients present features of Cockayne syndrome, including dwarfism, sensorineural deafness, microcephaly, mental retardation, pigmentary retinopathy, ataxia, decreased nerve conduction velocities. Belongs to the XPG/RAD2 endonuclease family. XPG subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA repair, damage; Deoxyribonuclease; EC 3.1.-.-

Chromosomal Location of Human Ortholog: 13q33

Cellular Component: DNA replication factor A complex; DNA-directed RNA polymerase II, holoenzyme; holo TFIIH complex; nucleoplasm; nucleus

Molecular Function: bubble DNA binding; double-stranded DNA binding; endodeoxyribonuclease activity; protein binding; protein homodimerization activity; protein N-terminus binding; single-stranded DNA binding

Biological Process: negative regulation of apoptosis; nucleotide-excision repair, DNA incision; nucleotide-excision repair, DNA incision, 3'-to lesion; nucleotide-excision repair, DNA incision, 5'-to lesion; nucleotide-excision repair, preincision complex assembly; nucleotide-excision repair, preincision complex stabilization; response to UV; response to UV-C; transcription-coupled nucleotide-excision repair; UV protection

Disease: Cerebrooculofacioskeletal Syndrome 3; Xeroderma Pigmentosum, Complementation Group G
 ERCC5 ELISA Kit
 ERCC5 Recombinant
 ERCC5 Antibody
 ERCM2 ELISA Kit
 ERCM2 Recombinant
 ERCM2 Antibody
 XPG ELISA Kit
 XPG Recombinant
 XPG Antibody
 XPGC ELISA Kit
 XPGC Recombinant
 XPGC Antibody
Table BarTOPTable Bar
 

DNA repair protein complementing XP-G cells homolog

 DNA repair protein complementing XP-G cells homolog ELISA Kit
 DNA repair protein complementing XP-G cells homolog Recombinant
 DNA repair protein complementing XP-G cells homolog Antibody
Also known as DNA repair protein complementing XP-G cells homolog (DNA excision repair protein ERCC-5) (Xeroderma pigmentosum group G-complementing protein homolog).
XPG: Single-stranded structure-specific DNA endonuclease involved in DNA excision repair. Makes the 3'incision in DNA nucleotide excision repair (NER). Acts as a cofactor for a DNA glycosylase that removes oxidized pyrimidines from DNA. May also be involved in transcription-coupled repair of this kind of damage, in transcription by RNA polymerase II, and perhaps in other processes too. Defects in ERCC5 are the cause of xeroderm
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a pigmentosum complementation group G (XP-G); also known as xeroderma pigmentosum VII (XP7). Xeroderma pigmentosum is an autosomal recessive pigmentary skin disorder characterized by solar hypersensitivity of the skin, high predisposition for developing cancers on areas exposed to sunlight and, in some cases, neurological abnormalities. Some XP-G patients present features of Cockayne syndrome, including dwarfism, sensorineural deafness, microcephaly, mental retardation, pigmentary retinopathy, ataxia, decreased nerve conduction velocities. Belongs to the XPG/RAD2 endonuclease family. XPG subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA repair, damage; Deoxyribonuclease; EC 3.1.-.-

Cellular Component: DNA replication factor A complex; DNA-directed RNA polymerase II, holoenzyme; holo TFIIH complex; nucleus

Molecular Function: bubble DNA binding; double-stranded DNA binding; endodeoxyribonuclease activity; protein homodimerization activity; protein N-terminus binding; single-stranded DNA binding

Biological Process: determination of adult life span; DNA repair; multicellular organism growth; negative regulation of apoptosis; nucleotide-excision repair; nucleotide-excision repair, DNA incision, 3'-to lesion; response to UV; response to UV-C; transcription-coupled nucleotide-excision repair; UV protection
 Ercc5 ELISA Kit
 Ercc5 Recombinant
 Ercc5 Antibody
 Ercc-5 ELISA Kit
 Ercc-5 Recombinant
 Ercc-5 Antibody
 Xpg ELISA Kit
 Xpg Recombinant
 Xpg Antibody
Table BarTOPTable Bar
 

DNA repair protein crb2

 DNA repair protein crb2 ELISA Kit
 DNA repair protein crb2 Recombinant
 DNA repair protein crb2 Antibody
Also known as DNA repair protein crb2 (Checkpoint mediator protein crb2) (Cut5-repeat binding protein 2) (RAD9 protein homolog).
Essential for cell cycle arrest at the G1 and G2 stages following DNA damage by X-, and UV-irradiation, or inactivation of DNA ligase. Plays a role in the response to DNA damage (PubMed:9153313, PubMed:9407031). Interaction with rad4 via its phosphorylation sites in the N-terminus couples the DNA checkpoint apparatus to chromatin via interaction of its C-terminal BRCT domains with epigenetic modifications on histones H4 and H2A, respectively, in the G1/S phase of
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the cell cycle, and facilitates recruitment of the checkpoint kinase chk1 (PubMed:15550243, PubMed:16778077, PubMed:18826944, PubMed:20679485, PubMed:22792081).
 crb2 ELISA Kit
 crb2 Recombinant
 crb2 Antibody
 rhp9 ELISA Kit
 rhp9 Recombinant
 rhp9 Antibody
 SPBC342.05 ELISA Kit
 SPBC342.05 Recombinant
 SPBC342.05 Antibody
Table BarTOPTable Bar
 

DNA repair protein homolog YobH

 DNA repair protein homolog YobH ELISA Kit
 DNA repair protein homolog YobH Recombinant
 DNA repair protein homolog YobH Antibody
 yobH ELISA Kit
 yobH Recombinant
 yobH Antibody
 BSU18930 ELISA Kit
 BSU18930 Recombinant
 BSU18930 Antibody
Table BarTOPTable Bar
 

DNA repair protein homolog YozK

 DNA repair protein homolog YozK ELISA Kit
 DNA repair protein homolog YozK Recombinant
 DNA repair protein homolog YozK Antibody
 yozK ELISA Kit
 yozK Recombinant
 yozK Antibody
 BSU18940 ELISA Kit
 BSU18940 Recombinant
 BSU18940 Antibody
Table BarTOPTable Bar
 

DNA repair protein KRE29

 DNA repair protein KRE29 ELISA Kit
 DNA repair protein KRE29 Recombinant
 DNA repair protein KRE29 Antibody
Also known as DNA repair protein KRE29 (Killer toxin-resistance protein 29).
Acts in a DNA repair pathway for removal of UV-induced DNA damage that is distinct from classical nucleotide excision repair and in repair of ionizing radiation damage. Functions in homologous recombination repair of DNA double strand breaks and in recovery of stalled replication forks.
 KRE29 ELISA Kit
 KRE29 Recombinant
 KRE29 Antibody
 YER038C ELISA Kit
 YER038C Recombinant
 YER038C Antibody
Table BarTOPTable Bar
 

DNA repair protein PprA

 DNA repair protein PprA ELISA Kit
 DNA repair protein PprA Recombinant
 DNA repair protein PprA Antibody
Also known as DNA repair protein PprA (Pleiotropic protein promoting DNA repair).
dsDNA-binding protein that contributes to the ionizing radiation resistance of D.radiodurans. Plays a role in DNA repair and genome reconstitution, and is necessary for recovery from severe genomic fragmentation as a result of exposure to severe levels of ionizing radiation. In vitro, binds to double-stranded DNA
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carrying strand breaks and stimulates the DNA end-joining reaction catalyzed by DNA ligases. Thus, PprA plays a critical role in a non-homologous end-joining (NHEJ) pathway for the repair of radiation-induced DNA double-strands breaks. Cannot bind to dsDNA without strand breaks or single-stranded DNA.
 pprA ELISA Kit
 pprA Recombinant
 pprA Antibody
 DR_A0346 ELISA Kit
 DR_A0346 Recombinant
 DR_A0346 Antibody
Table BarTOPTable Bar
 

DNA repair protein RAD1

 DNA repair protein RAD1 ELISA Kit
 DNA repair protein RAD1 Recombinant
 DNA repair protein RAD1 Antibody
Involved in nucleotide excision repair of DNA damaged with UV light, bulky adducts, or cross-linking agents. Along with RAD10 forms an endonuclease that specifically degrades single-stranded DNA.
 RAD1 ELISA Kit
 RAD1 Recombinant
 RAD1 Antibody
 YPL022W ELISA Kit
 YPL022W Recombinant
 YPL022W Antibody
Table BarTOPTable Bar
 

DNA repair protein RAD10

 DNA repair protein RAD10 ELISA Kit
 DNA repair protein RAD10 Recombinant
 DNA repair protein RAD10 Antibody
Involved in nucleotide excision repair of DNA damaged with UV light, bulky adducts, or cross-linking agents. Along with RAD1 forms an endonuclease that specifically degrades single-stranded DNA.
 RAD10 ELISA Kit
 RAD10 Recombinant
 RAD10 Antibody
 YML095C ELISA Kit
 YML095C Recombinant
 YML095C Antibody
Table BarTOPTable Bar
 

DNA repair protein rad13

 DNA repair protein rad13 ELISA Kit
 DNA repair protein rad13 Recombinant
 DNA repair protein rad13 Antibody
Single-stranded DNA endonuclease involved in excision repair of DNA damaged with UV light, bulky adducts, or cross-linking agents. Essential for the incision step of excision-repair (Probable).
 rad13 ELISA Kit
 rad13 Recombinant
 rad13 Antibody
 SPBC3E7.08c ELISA Kit
 SPBC3E7.08c Recombinant
 SPBC3E7.08c Antibody
Table BarTOPTable Bar
 

DNA repair protein RAD14

 DNA repair protein RAD14 ELISA Kit
 DNA repair protein RAD14 Recombinant
 DNA repair protein RAD14 Antibody
Involved in nucleotide excision repair. Binds specifically to damaged DNA. Required for the incision step.
 RAD14 ELISA Kit
 RAD14 Recombinant
 RAD14 Antibody
 YMR201C ELISA Kit
 YMR201C Recombinant
 YMR201C Antibody
 YM8325.02C ELISA Kit
 YM8325.02C Recombinant
 YM8325.02C Antibody
Table BarTOPTable Bar
 

DNA repair protein rad16

 DNA repair protein rad16 ELISA Kit
 DNA repair protein rad16 Recombinant
 DNA repair protein rad16 Antibody
Endonuclease that specifically degrades single-stranded DNA and which is involved in nucleotide excision repair of DNA damaged with UV light, bulky adducts, or cross-linking agents. Required for double strand break-induced interchromosomal gene conversion.
 rad16 ELISA Kit
 rad16 Recombinant
 rad16 Antibody
 rad10 ELISA Kit
 rad10 Recombinant
 rad10 Antibody
 rad20 ELISA Kit
 rad20 Recombinant
 rad20 Antibody
 swi9 ELISA Kit
 swi9 Recombinant
 swi9 Antibody
Table BarTOPTable Bar
 

DNA repair protein RAD2

 DNA repair protein RAD2 ELISA Kit
 DNA repair protein RAD2 Recombinant
 DNA repair protein RAD2 Antibody
Single-stranded DNA endonuclease involved in excision repair of DNA damaged with UV light, bulky adducts, or cross-linking agents. Essential for the incision step of excision-repair.
 RAD2 ELISA Kit
 RAD2 Recombinant
 RAD2 Antibody
 YGR258C ELISA Kit
 YGR258C Recombinant
 YGR258C Antibody
Table BarTOPTable Bar
 

DNA repair protein rad26

 DNA repair protein rad26 ELISA Kit
 DNA repair protein rad26 Recombinant
 DNA repair protein rad26 Antibody
Involved in cell cycle arrest when DNA synthesis is inhibited by hydroxyurea, and in mitosis arrest after treatment with DNA-damaging agents. This protein is S phase-specific.
 rad26 ELISA Kit
 rad26 Recombinant
 rad26 Antibody
 SPAC9E9.08 ELISA Kit
 SPAC9E9.08 Recombinant
 SPAC9E9.08 Antibody
Table BarTOPTable Bar
 

DNA repair protein rad32

 DNA repair protein rad32 ELISA Kit
 DNA repair protein rad32 Recombinant
 DNA repair protein rad32 Antibody
Required for the repair of double strand breaks (DSB) caused by gamma and UV radiation. May work in conjunction with rhp51.
 rad32 ELISA Kit
 rad32 Recombinant
 rad32 Antibody
 SPAC13C5.07 ELISA Kit
 SPAC13C5.07 Recombinant
 SPAC13C5.07 Antibody
Table BarTOPTable Bar
 

DNA repair protein RAD33

 DNA repair protein RAD33 ELISA Kit
 DNA repair protein RAD33 Recombinant
 DNA repair protein RAD33 Antibody
Involved in nucleotide excision repair (NER) of damaged DNA. Required for the repair of RNA polymerase I-transcribed rDNA and RNA polymerase II-transcribed DNA regions. May have a role in stabilizing the DNA repair proteins RAD4 and RAD34.
 RAD33 ELISA Kit
 RAD33 Recombinant
 RAD33 Antibody
 YML011C ELISA Kit
 YML011C Recombinant
 YML011C Antibody
 YM9571.07C ELISA Kit
 YM9571.07C Recombinant
 YM9571.07C Antibody
Table BarTOPTable Bar
 

DNA repair protein RAD34

 DNA repair protein RAD34 ELISA Kit
 DNA repair protein RAD34 Recombinant
 DNA repair protein RAD34 Antibody
Involved in nucleotide excision repair (NER) of damaged ribosomal DNA (rDNA). Required for the repair of the RNA polymerase I-transcribed strand of rDNA.
 RAD34 ELISA Kit
 RAD34 Recombinant
 RAD34 Antibody
 YDR314C ELISA Kit
 YDR314C Recombinant
 YDR314C Antibody
Table BarTOPTable Bar
 

DNA repair protein RAD4

 DNA repair protein RAD4 ELISA Kit
 DNA repair protein RAD4 Recombinant
 DNA repair protein RAD4 Antibody
Involved in nucleotide excision repair of DNA damaged with UV light, bulky adducts, or cross-linking agents.
 RAD4 ELISA Kit
 RAD4 Recombinant
 RAD4 Antibody
 YER162C ELISA Kit
 YER162C Recombinant
 YER162C Antibody
Table BarTOPTable Bar
 

DNA repair protein RAD5

 DNA repair protein RAD5 ELISA Kit
 DNA repair protein RAD5 Recombinant
 DNA repair protein RAD5 Antibody
Probable helicase, member of the UBC2/RAD6 epistasis group. Functions with DNA repair protein RAD18 in error-free postreplication DNA repair. Involved in the maintenance of wild-type rates of instability of simple repetitive sequences such as poly(GT) repeats. Seems to be involved in maintaining a balance which acts in favor of error-prone non-homologous joining during DNA double-strand breaks repairs ().
 RAD5 ELISA Kit
 RAD5 Recombinant
 RAD5 Antibody
 FGRRES_02724 ELISA Kit
 FGRRES_02724 Recombinant
 FGRRES_02724 Antibody
 FGSG_02724 ELISA Kit
 FGSG_02724 Recombinant
 FGSG_02724 Antibody
Table BarTOPTable Bar
 

DNA repair protein RAD50

 DNA repair protein RAD50 ELISA Kit
 DNA repair protein RAD50 Recombinant
 DNA repair protein RAD50 Antibody
Involved in DNA double-strand break repair (DSBR). The RAD50/MRE11 complex possesses single-strand endonuclease activity and ATP-dependent double-strand-specific exonuclease activity. RAD50 provides ATP-dependent control of MRE11 by unwinding and/or repositioning DNA ends into the MRE11 active site ().
 RAD50 ELISA Kit
 RAD50 Recombinant
 RAD50 Antibody
 ECU07_0610i ELISA Kit
 ECU07_0610i Recombinant
 ECU07_0610i Antibody
Table BarTOPTable Bar
 

DNA repair protein rad-50

 DNA repair protein rad-50 ELISA Kit
 DNA repair protein rad-50 Recombinant
 DNA repair protein rad-50 Antibody
Essential component of the MRN complex, a complex that possesses single-stranded DNA endonuclease and 3' to 5' exonuclease activities, and plays a central role in double-strand break (DSB) repair, chromosome morphogenesis, DNA repair and meiosis. In the complex, it mediates the ATP-binding and is probably required to bind DNA ends and hold them in close proximity.
 rad-50 ELISA Kit
 rad-50 Recombinant
 rad-50 Antibody
 T04H1.4 ELISA Kit
 T04H1.4 Recombinant
 T04H1.4 Antibody
Table BarTOPTable Bar
 

DNA repair protein RAD51

 DNA repair protein RAD51 ELISA Kit
 DNA repair protein RAD51 Recombinant
 DNA repair protein RAD51 Antibody
Required both for recombination and for the repair of DNA damage caused by X-rays. Its function may be modulated by interaction with other repair proteins. RAD52 interacts directly with RAD51, via its C-terminus. Forms a nucleoprotein filament with DNA as an early intermediate in recombination.
 RAD51 ELISA Kit
 RAD51 Recombinant
 RAD51 Antibody
 YER095W ELISA Kit
 YER095W Recombinant
 YER095W Antibody
Table BarTOPTable Bar
 

DNA repair protein RAD51 homolog

 DNA repair protein RAD51 homolog ELISA Kit
 DNA repair protein RAD51 homolog Recombinant
 DNA repair protein RAD51 homolog Antibody
Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Underwinds duplex DNA ().
 RAD51 ELISA Kit
 RAD51 Recombinant
 RAD51 Antibody
Table BarTOPTable Bar
 

DNA repair protein RAD51 homolog 1

 DNA repair protein RAD51 homolog 1 ELISA Kit
 DNA repair protein RAD51 homolog 1 Recombinant
 DNA repair protein RAD51 homolog 1 Antibody
Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination (HR). Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DN
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A in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Part of a PALB2-scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3. Also involved in interstrand cross-link repair.
 RAD51 ELISA Kit
 RAD51 Recombinant
 RAD51 Antibody
 RAD51A ELISA Kit
 RAD51A Recombinant
 RAD51A Antibody
Table BarTOPTable Bar
 

DNA repair protein RAD51 homolog 2

 DNA repair protein RAD51 homolog 2 ELISA Kit
 DNA repair protein RAD51 homolog 2 Recombinant
 DNA repair protein RAD51 homolog 2 Antibody
Also known as DNA repair protein RAD51 homolog 2 (AtRAD51B).
Encodes a protein of the RAD51B family involved in double stranded DNA repair. Homozygous mutant plants show increased sensitivity to mitomycin which induces DS breaks.
 RAD51B ELISA Kit
 RAD51B Recombinant
 RAD51B Antibody
 At2g28560 ELISA Kit
 At2g28560 Recombinant
 At2g28560 Antibody
 T17D12.12 ELISA Kit
 T17D12.12 Recombinant
 T17D12.12 Antibody
Table BarTOPTable Bar
 

DNA repair protein RAD51 homolog 3

 DNA repair protein RAD51 homolog 3 ELISA Kit
 DNA repair protein RAD51 homolog 3 Recombinant
 DNA repair protein RAD51 homolog 3 Antibody
Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents.
 rad51c ELISA Kit
 rad51c Recombinant
 rad51c Antibody
 DDB_G0284507 ELISA Kit
 DDB_G0284507 Recombinant
 DDB_G0284507 Antibody
Table BarTOPTable Bar
 

DNA repair protein RAD51 homolog 4

 DNA repair protein RAD51 homolog 4 ELISA Kit
 DNA repair protein RAD51 homolog 4 Recombinant
 DNA repair protein RAD51 homolog 4 Antibody
Also known as DNA repair protein RAD51 homolog 4 (AtRAD51D).
Is a suppressor of SNI1. Encodes a member of the RecA/RAD51 family of DNA recombination and repair proteins. Both RAD51 and SNI1 have a dual role in pathogen-related gene transcription and somatic homologous recombination.
 RAD51D ELISA Kit
 RAD51D Recombinant
 RAD51D Antibody
 At1g07745 ELISA Kit
 At1g07745 Recombinant
 At1g07745 Antibody
 F24B9.14 ELISA Kit
 F24B9.14 Recombinant
 F24B9.14 Antibody
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DNA repair protein RAD51 homolog A

 DNA repair protein RAD51 homolog A ELISA Kit
 DNA repair protein RAD51 homolog A Recombinant
 DNA repair protein RAD51 homolog A Antibody
Also known as DNA repair protein RAD51 homolog A (Rad51-like protein A) (RAD51A) (ZmRAD51a).
Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Unwinds duplex DNA (). Component of the meiotic recombination pathway. Seems to play a role in mediating chromosome homology search, chromosome pairing and synapsis at early stages and probably chromosome crossing-over a
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t later stages in meiosis. Probably is involved in the repair of meiotic double strand breaks (DBSs) and in homologous recombination.
 RAD51A ELISA Kit
 RAD51A Recombinant
 RAD51A Antibody
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DNA repair protein RAD51 homolog B

 DNA repair protein RAD51 homolog B ELISA Kit
 DNA repair protein RAD51 homolog B Recombinant
 DNA repair protein RAD51 homolog B Antibody
Also known as DNA repair protein RAD51 homolog B (Rad51-like protein B) (RAD51B) (ZmRAD51b).
Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Unwinds duplex DNA (). Component of the meiotic recombination pathway. Seems to play a role in mediating chromosome homology search, chromosome pairing and synapsis at early stages and probably chromosome crossing-over a
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t later stages in meiosis. Probably is involved in the repair of meiotic double strand breaks (DBSs) and in homologous recombination.
 RAD51B ELISA Kit
 RAD51B Recombinant
 RAD51B Antibody
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DNA repair protein RAD52 homolog

 DNA repair protein RAD52 homolog ELISA Kit
 DNA repair protein RAD52 homolog Recombinant
 DNA repair protein RAD52 homolog Antibody
RAD52: a protein involved in DNA double strand breaks and recombination. Associates with and is phosphorylated by c-Abl. Belongs to the RAD52/RAD22 family.

Protein type: DNA repair, damage

Cellular Component: nucleus; protein complex

Molecular Function: DNA binding; identical protein binding

Biological Process: DNA recombination; double-strand break repair via homologo
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us recombination; response to DNA damage stimulus
 Rad52 ELISA Kit
 Rad52 Recombinant
 Rad52 Antibody
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DNA repair protein RAD55

 DNA repair protein RAD55 ELISA Kit
 DNA repair protein RAD55 Recombinant
 DNA repair protein RAD55 Antibody
Required for radiation resistance and meiotic viability and presumably acts in recombination and recombinational DNA repair pathways.
 RAD55 ELISA Kit
 RAD55 Recombinant
 RAD55 Antibody
 YDR076W ELISA Kit
 YDR076W Recombinant
 YDR076W Antibody
 D4426 ELISA Kit
 D4426 Recombinant
 D4426 Antibody
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DNA repair protein RAD57

 DNA repair protein RAD57 ELISA Kit
 DNA repair protein RAD57 Recombinant
 DNA repair protein RAD57 Antibody
Participates in the repair of X-ray-induced damage to DNA and in meiosis. It may act in part by stabilizing a repair complex of other RAD genes.
 RAD57 ELISA Kit
 RAD57 Recombinant
 RAD57 Antibody
 YDR004W ELISA Kit
 YDR004W Recombinant
 YDR004W Antibody
 YD8119.10 ELISA Kit
 YD8119.10 Recombinant
 YD8119.10 Antibody
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DNA repair protein RAD59

 DNA repair protein RAD59 ELISA Kit
 DNA repair protein RAD59 Recombinant
 DNA repair protein RAD59 Antibody
Involved in the repair of double-strand breaks in DNA during vegetative growth via recombination and single-strand annealing. Anneals complementary single-stranded DNA ().
 RAD59 ELISA Kit
 RAD59 Recombinant
 RAD59 Antibody
 AER046W ELISA Kit
 AER046W Recombinant
 AER046W Antibody
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DNA repair protein rad60

 DNA repair protein rad60 ELISA Kit
 DNA repair protein rad60 Recombinant
 DNA repair protein rad60 Antibody
Required for repair of DNA double strand breaks which occur during replication, or induced by UV or gamma radiation, via recombination between sister chromatids. This has a subsequent role in the maintenance of chromosome structure. May work in conjunction with the Smc5-Smc6 complex.
 rad60 ELISA Kit
 rad60 Recombinant
 rad60 Antibody
 SPBC1921.02 ELISA Kit
 SPBC1921.02 Recombinant
 SPBC1921.02 Antibody
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DNA repair protein RAD7

 DNA repair protein RAD7 ELISA Kit
 DNA repair protein RAD7 Recombinant
 DNA repair protein RAD7 Antibody
Component of the global genome repair (GGR) complex which promotes global genome nucleotide excision repair (GG-NER) which removes DNA damage from nontranscribing DNA. This protein is one of 10 proteins (RAD1, 2,3,4,7,10,14, 16,23 and MMS19) involved in excision repair of DNA damaged with UV light, bulky adducts, or cross-linking agents.
 RAD7 ELISA Kit
 RAD7 Recombinant
 RAD7 Antibody
 YJR052W ELISA Kit
 YJR052W Recombinant
 YJR052W Antibody
 J1665 ELISA Kit
 J1665 Recombinant
 J1665 Antibody
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DNA repair protein rad8

 DNA repair protein rad8 ELISA Kit
 DNA repair protein rad8 Recombinant
 DNA repair protein rad8 Antibody
Also known as DNA repair protein rad8 (DNA repair protein RAD5 homolog).
Probable helicase, member of the UBC2/RAD6 epistasis group. Functions with DNA repair protein rad18 in error-free postreplication DNA repair. Involved in the maintenance of wild-type rates of instability of simple repetitive sequences such as poly(GT) repeats (). Plays a role in surviving topoisomerase-mediated DNA damage (PubMed:14871939).
 rad8 ELISA Kit
 rad8 Recombinant
 rad8 Antibody
 SPAC13G6.01c ELISA Kit
 SPAC13G6.01c Recombinant
 SPAC13G6.01c Antibody
 SPAC5H10.14c ELISA Kit
 SPAC5H10.14c Recombinant
 SPAC5H10.14c Antibody
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DNA repair protein RAD9

 DNA repair protein RAD9 ELISA Kit
 DNA repair protein RAD9 Recombinant
 DNA repair protein RAD9 Antibody
Essential for cell cycle arrest at the G2 stage following DNA damage by X-irradiation or inactivation of DNA ligase.
 RAD9 ELISA Kit
 RAD9 Recombinant
 RAD9 Antibody
 YDR217C ELISA Kit
 YDR217C Recombinant
 YDR217C Antibody
 YD9934.02C ELISA Kit
 YD9934.02C Recombinant
 YD9934.02C Antibody
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DNA repair protein RadA

 DNA repair protein RadA ELISA Kit
 DNA repair protein RadA Recombinant
 DNA repair protein RadA Antibody
Also known as DNA repair protein RadA (Branch migration protein RadA).
DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATP
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ase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
 radA ELISA Kit
 radA Recombinant
 radA Antibody
 DR_1105 ELISA Kit
 DR_1105 Recombinant
 DR_1105 Antibody
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DNA repair protein rdl1

 DNA repair protein rdl1 ELISA Kit
 DNA repair protein rdl1 Recombinant
 DNA repair protein rdl1 Antibody
Also known as DNA repair protein rdl1 (RAD51D-like protein 1).
Involved in homologous recombination where it functions at an early stage of recombination in a pre-recombinogenic complex with rlp1 and sws1. Also has a role at a later stage of recombination in association with the rhp55-rhp57 complex.
 rdl1 ELISA Kit
 rdl1 Recombinant
 rdl1 Antibody
 SPAC17H9.03c ELISA Kit
 SPAC17H9.03c Recombinant
 SPAC17H9.03c Antibody
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DNA repair protein recA homolog 1

 DNA repair protein recA homolog 1 ELISA Kit
 DNA repair protein recA homolog 1 Recombinant
 DNA repair protein recA homolog 1 Antibody
Also known as DNA repair protein recA homolog 1, chloroplastic (Recombinase A homolog 1).
Involved in recombination ability and DNA strand transfer activity.
 RECA ELISA Kit
 RECA Recombinant
 RECA Antibody
 At1g79050 ELISA Kit
 At1g79050 Recombinant
 At1g79050 Antibody
 YUP8H12R.33 ELISA Kit
 YUP8H12R.33 Recombinant
 YUP8H12R.33 Antibody
 YUP8H12R_18 ELISA Kit
 YUP8H12R_18 Recombinant
 YUP8H12R_18 Antibody
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DNA repair protein recA homolog 2

 DNA repair protein recA homolog 2 ELISA Kit
 DNA repair protein recA homolog 2 Recombinant
 DNA repair protein recA homolog 2 Antibody
Also known as DNA repair protein recA homolog 2, mitochondrial (Recombinase A homolog 2).
Encodes a gene involved in plant mitochondrial recombination surveillance. Disruption of this gene in combination with a mutation in MSH1 results in extensive rearrangement of the mitochondrial genome and dramatic changes in plant growth.
 At3g10140 ELISA Kit
 At3g10140 Recombinant
 At3g10140 Antibody
 T22K18.3 ELISA Kit
 T22K18.3 Recombinant
 T22K18.3 Antibody
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DNA repair protein recA homolog 3

 DNA repair protein recA homolog 3 ELISA Kit
 DNA repair protein recA homolog 3 Recombinant
 DNA repair protein recA homolog 3 Antibody
Also known as DNA repair protein recA homolog 3, mitochondrial (Recombinase A homolog 3).
Involved in recombination ability and DNA strand transfer activity.
 At2g19490 ELISA Kit
 At2g19490 Recombinant
 At2g19490 Antibody
 F3P11.9 ELISA Kit
 F3P11.9 Recombinant
 F3P11.9 Antibody
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DNA repair protein RecN

 DNA repair protein RecN ELISA Kit
 DNA repair protein RecN Recombinant
 DNA repair protein RecN Antibody
Also known as DNA repair protein RecN (Recombination protein N).
May be involved in recombinational repair of damaged DNA.
 recN ELISA Kit
 recN Recombinant
 recN Antibody
 Cj0642 ELISA Kit
 Cj0642 Recombinant
 Cj0642 Antibody
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DNA repair protein RecO

 DNA repair protein RecO ELISA Kit
 DNA repair protein RecO Recombinant
 DNA repair protein RecO Antibody
Also known as DNA repair protein RecO (Recombination protein O).
Involved in DNA repair and RecF pathway recombination.
 recO ELISA Kit
 recO Recombinant
 recO Antibody
 Acry_1209 ELISA Kit
 Acry_1209 Recombinant
 Acry_1209 Antibody
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DNA repair protein REV1

 DNA repair protein REV1 ELISA Kit
 DNA repair protein REV1 Recombinant
 DNA repair protein REV1 Antibody
Also known as DNA repair protein REV1 (Alpha integrin-binding protein 80) (AIBP80) (Rev1-like terminal deoxycytidyl transferase).
REV1L: Deoxycytidyl transferase involved in DNA repair. Transfers a dCMP residue from dCTP to the 3'-end of a DNA primer in a template-dependent reaction. May assist in the first step in the bypass of abasic lesions by the insertion of a nucleotide opposite the lesio
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n. Required for normal induction of mutations by physical and chemical agents. Belongs to the DNA polymerase type-Y family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: DNA repair, damage; EC 2.7.7.-; Transferase

Chromosomal Location of Human Ortholog: 2q11.1-q11.2

Cellular Component: nucleoplasm

Molecular Function: deoxycytidyl transferase activity; protein binding

Biological Process: bypass DNA synthesis; DNA replication; error-prone postreplication DNA repair; response to UV
 REV1 ELISA Kit
 REV1 Recombinant
 REV1 Antibody
 REV1L ELISA Kit
 REV1L Recombinant
 REV1L Antibody
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DNA repair protein rhp26

 DNA repair protein rhp26 ELISA Kit
 DNA repair protein rhp26 Recombinant
 DNA repair protein rhp26 Antibody
Also known as DNA repair protein rhp26 (RAD26 homolog).
Involved in transcription-coupled repair (TCR).
 rhp26 ELISA Kit
 rhp26 Recombinant
 rhp26 Antibody
 SPCP25A2.02c ELISA Kit
 SPCP25A2.02c Recombinant
 SPCP25A2.02c Antibody
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DNA repair protein rhp41

 DNA repair protein rhp41 ELISA Kit
 DNA repair protein rhp41 Recombinant
 DNA repair protein rhp41 Antibody
Has a role in the nucleotide excision repair (NER) pathway. Acts in both transcription-coupled repair (TCR) which removes damage from the transcribed strand of active genes and in global genome repair (GGR) which removes damage in untranscribed DNA. Involved in the repair of UV-induced damages where it is involved in the removal of cyclobutane pyrimidine dimers (CPDs).
 rhp41 ELISA Kit
 rhp41 Recombinant
 rhp41 Antibody
 rhp4a ELISA Kit
 rhp4a Recombinant
 rhp4a Antibody
 SPAC12B10.12c ELISA Kit
 SPAC12B10.12c Recombinant
 SPAC12B10.12c Antibody
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DNA repair protein rhp42

 DNA repair protein rhp42 ELISA Kit
 DNA repair protein rhp42 Recombinant
 DNA repair protein rhp42 Antibody
Has a role in the nucleotide excision repair (NER) pathway. Acts in both transcription-coupled repair (TCR) which removes damage from the transcribed strand of active genes and in global genome repair (GGR) which removes damage in untranscribed DNA. Involved in the repair of short-patch mismatch during meiosis.
 rhp42 ELISA Kit
 rhp42 Recombinant
 rhp42 Antibody
 rhp4b ELISA Kit
 rhp4b Recombinant
 rhp4b Antibody
 SPCC4G3.10c ELISA Kit
 SPCC4G3.10c Recombinant
 SPCC4G3.10c Antibody
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DNA repair protein rhp51

 DNA repair protein rhp51 ELISA Kit
 DNA repair protein rhp51 Recombinant
 DNA repair protein rhp51 Antibody
Also known as DNA repair protein rhp51 (RAD51 homolog).
Required both for recombination and for the repair of DNA damage caused by X-rays. Binds to single and double-stranded DNA, in the presence of magnesium, and exhibits DNA-dependent ATPase activity. Promotes DNA strand annealing and strand exchange via DNA recombinase activity and forms helical nucleoprotein filaments.
 rhp51 ELISA Kit
 rhp51 Recombinant
 rhp51 Antibody
 rad51 ELISA Kit
 rad51 Recombinant
 rad51 Antibody
 SPAC644.14c ELISA Kit
 SPAC644.14c Recombinant
 SPAC644.14c Antibody
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DNA repair protein rhp54

 DNA repair protein rhp54 ELISA Kit
 DNA repair protein rhp54 Recombinant
 DNA repair protein rhp54 Antibody
Also known as DNA repair protein rhp54 (RAD54 homolog 1).
Involved in DNA repair. May have a role in the processing of replication structures during late replication that is different from its role in the repair of radiation damage.
 rhp54 ELISA Kit
 rhp54 Recombinant
 rhp54 Antibody
 rad54 ELISA Kit
 rad54 Recombinant
 rad54 Antibody
 SPAC15A10.03c ELISA Kit
 SPAC15A10.03c Recombinant
 SPAC15A10.03c Antibody
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DNA repair protein rhp55

 DNA repair protein rhp55 ELISA Kit
 DNA repair protein rhp55 Recombinant
 DNA repair protein rhp55 Antibody
Also known as DNA repair protein rhp55 (RAD55 homolog).
Required for radiation resistance and meiotic viability and acts in recombination and recombinational DNA repair pathways.
 rhp55 ELISA Kit
 rhp55 Recombinant
 rhp55 Antibody
 SPAC3C7.03c ELISA Kit
 SPAC3C7.03c Recombinant
 SPAC3C7.03c Antibody
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DNA repair protein rhp57

 DNA repair protein rhp57 ELISA Kit
 DNA repair protein rhp57 Recombinant
 DNA repair protein rhp57 Antibody
Also known as DNA repair protein rhp57 (RAD57 homolog).
Involved in recombination DNA repair and in the repair of gamma-ray-induced damage.
 rhp57 ELISA Kit
 rhp57 Recombinant
 rhp57 Antibody
 SPAC145.01 ELISA Kit
 SPAC145.01 Recombinant
 SPAC145.01 Antibody
 SPAC20H4.07 ELISA Kit
 SPAC20H4.07 Recombinant
 SPAC20H4.07 Antibody
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DNA repair protein rhp7

 DNA repair protein rhp7 ELISA Kit
 DNA repair protein rhp7 Recombinant
 DNA repair protein rhp7 Antibody
Also known as DNA repair protein rhp7 (RAD7 homolog).
Involved in global genome repair (GGR) via nucleotide excision repair (NER), in conjunction with rhp16, after UV irradiation.
 rhp7 ELISA Kit
 rhp7 Recombinant
 rhp7 Antibody
 SPCC330.02 ELISA Kit
 SPCC330.02 Recombinant
 SPCC330.02 Antibody
 SPCC613.14 ELISA Kit
 SPCC613.14 Recombinant
 SPCC613.14 Antibody
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DNA repair protein rlp1

 DNA repair protein rlp1 ELISA Kit
 DNA repair protein rlp1 Recombinant
 DNA repair protein rlp1 Antibody
Also known as DNA repair protein rlp1 (RecA-like protein 1).
Required for normal levels of meiotic recombination. Acts in the recombinational pathway of double-strand break (DSB) repair together with rhp51, rhp55 and rad22. Required for the full extent of DNA recombination and cell survival under condition of a replication fork collapse.
 rlp1 ELISA Kit
 rlp1 Recombinant
 rlp1 Antibody
 SPBC1685.11 ELISA Kit
 SPBC1685.11 Recombinant
 SPBC1685.11 Antibody
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DNA repair protein SWI5 homolog

 DNA repair protein SWI5 homolog ELISA Kit
 DNA repair protein SWI5 homolog Recombinant
 DNA repair protein SWI5 homolog Antibody
Also known as DNA repair protein SWI5 homolog (HBV DNAPTP1-transactivated protein A) (Protein SAE3 homolog).
SWI5: Component of the SWI5-SFR1 complex, a complex required for double-strand break repair via homologous recombination. Belongs to the SWI5/SAE3 family.

Protein type: DNA repair, damage

Chromosomal Location of Human Ortholog: 9q34.11

Cellular Component: nucleus

Molecular Function: protein binding

Biological Process: DNA recombinase assembly; double-strand break repair via homologous recombination
 SWI5 ELISA Kit
 SWI5 Recombinant
 SWI5 Antibody
 C9orf119 ELISA Kit
 C9orf119 Recombinant
 C9orf119 Antibody
 SAE3 ELISA Kit
 SAE3 Recombinant
 SAE3 Antibody
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DNA repair protein UVH3

 DNA repair protein UVH3 ELISA Kit
 DNA repair protein UVH3 Recombinant
 DNA repair protein UVH3 Antibody
Also known as DNA repair protein UVH3 (ERCC5 homolog) (RAD2 homolog) (AtRAD2) (AtUVH3) (AtXPG) (UV hypersensitive protein 3) (XPG homolog).
Putative single-stranded DNA endonuclease involved in nucleotide excision repair (NER) of UV- and oxidative damaged DNA. May make the 3'-incision step in NER. Seems to play a role in senescence program.
 UVH3 ELISA Kit
 UVH3 Recombinant
 UVH3 Antibody
 RAD2 ELISA Kit
 RAD2 Recombinant
 RAD2 Antibody
 XPG ELISA Kit
 XPG Recombinant
 XPG Antibody
 At3g28030 ELISA Kit
 At3g28030 Recombinant
 At3g28030 Antibody
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DNA repair protein XRCC1

 DNA repair protein XRCC1 ELISA Kit
 DNA repair protein XRCC1 Recombinant
 DNA repair protein XRCC1 Antibody
Also known as DNA repair protein XRCC1 (X-ray repair cross-complementing protein 1).
XRCC1: Corrects defective DNA strand-break repair and sister chromatid exchange following treatment with ionizing radiation and alkylating agents. Homodimer. Interacts with polynucleotide kinase (PNK), DNA polymerase-beta (POLB) and DNA ligase III (LIG3). Interacts with APTX and APLF. Interacts with APEX1; the
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interaction is induced by SIRT1 and increases with the acetylated form of APEX1.

Protein type: DNA repair, damage

Cellular Component: nucleus

Molecular Function: enzyme binding

Biological Process: base-excision repair; DNA repair; hippocampus development
 Xrcc1 ELISA Kit
 Xrcc1 Recombinant
 Xrcc1 Antibody
 Xrcc-1 ELISA Kit
 Xrcc-1 Recombinant
 Xrcc-1 Antibody
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DNA repair protein XRCC2

 DNA repair protein XRCC2 ELISA Kit
 DNA repair protein XRCC2 Recombinant
 DNA repair protein XRCC2 Antibody
Also known as DNA repair protein XRCC2 (X-ray repair cross-complementing protein 2).
XRCC2: Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions. The BCDX2 complex binds single-stranded DNA, single-stranded gaps in duplex DNA and specifically to nicks in duplex DNA. Belongs to the RecA fam
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ily. RAD51 subfamily.

Cellular Component: centrosome; replication fork

Molecular Function: DNA-dependent ATPase activity; double-stranded DNA binding; endodeoxyribonuclease activity; four-way junction DNA binding; protein binding; recombinase activity; single-stranded DNA binding

Biological Process: centrosome organization and biogenesis; DNA repair; double-strand break repair via homologous recombination; in utero embryonic development; meiotic DNA recombinase assembly; meiotic recombination; mitotic cell cycle; mitotic recombination; multicellular organism growth; negative regulation of neuron apoptosis; neurogenesis; positive regulation of neurogenesis; response to DNA damage stimulus; response to gamma radiation; response to X-ray; somitogenesis; strand invasion
 Xrcc2 ELISA Kit
 Xrcc2 Recombinant
 Xrcc2 Antibody
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DNA repair protein XRCC2 homolog

 DNA repair protein XRCC2 homolog ELISA Kit
 DNA repair protein XRCC2 homolog Recombinant
 DNA repair protein XRCC2 homolog Antibody
Also known as DNA repair protein XRCC2 homolog (X-ray repair cross-complementing protein 2 homolog) (AtXRCC2).
Encodes a protein of the XRCC2 family involved in DNA repair. atxrcc2-1 Mutants are sensitive to MitomycinC but do not show fertility defects.
 XRCC2 ELISA Kit
 XRCC2 Recombinant
 XRCC2 Antibody
 At5g64520 ELISA Kit
 At5g64520 Recombinant
 At5g64520 Antibody
 T12B11.11 ELISA Kit
 T12B11.11 Recombinant
 T12B11.11 Antibody
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DNA repair protein XRCC3

 DNA repair protein XRCC3 ELISA Kit
 DNA repair protein XRCC3 Recombinant
 DNA repair protein XRCC3 Antibody
Also known as DNA repair protein XRCC3 (X-ray repair cross-complementing protein 3).
XRCC3: Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51 and RAD51C. Defects in XR
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CC3 are the cause of susceptibility to breast cancer (BC). BC is a common malignancy originating from breast epithelial tissue. Breast neoplasms can be distinguished by their histologic pattern. Invasive ductal carcinoma is by far the most common type. Breast cancer is etiologically and genetically heterogeneous. Important genetic factors have been indicated by familial occurrence and bilateral involvement. Mutations at more than one locus can be involved in different families or even in the same case. Defects in XRCC3 are the cause of susceptibility to cutaneous malignant melanoma type 6 (CMM6). CMM6 is a malignant neoplasm of melanocytes, arising de novo or from a pre- existing benign nevus, which occurs most often in the skin but also may involve other sites. Belongs to the RecA family. RAD51 subfamily.

Protein type: DNA repair, damage

Chromosomal Location of Human Ortholog: 14q32.3

Cellular Component: cytoplasm; mitochondrion; nuclear chromosome, telomeric region; nucleoplasm; nucleus; perinuclear region of cytoplasm; replication fork

Molecular Function: crossover junction endodeoxyribonuclease activity; DNA-dependent ATPase activity; double-stranded DNA binding; four-way junction DNA binding; protein binding; recombinase activity; single-stranded DNA binding

Biological Process: DNA recombination; DNA repair; DNA synthesis during DNA repair; double-strand break repair via homologous recombination; meiotic DNA recombinase assembly; meiotic recombination; response to DNA damage stimulus; response to ionizing radiation; strand displacement; strand invasion; telomere maintenance via recombination

Disease: Breast Cancer; Melanoma, Cutaneous Malignant, Susceptibility To, 6
 XRCC3 ELISA Kit
 XRCC3 Recombinant
 XRCC3 Antibody
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DNA repair protein XRCC3 homolog

 DNA repair protein XRCC3 homolog ELISA Kit
 DNA repair protein XRCC3 homolog Recombinant
 DNA repair protein XRCC3 homolog Antibody
Also known as DNA repair protein XRCC3 homolog (X-ray repair cross-complementing protein 3 homolog) (AtXRCC3).
Involved in homologous recombination and recombinational repair, mutants are sterile, hypersensitive to DNA crosslinking agents, show aberrant meiosis with extensive chromosome fragmentation
 XRCC3 ELISA Kit
 XRCC3 Recombinant
 XRCC3 Antibody
 At5g57450 ELISA Kit
 At5g57450 Recombinant
 At5g57450 Antibody
 MUA2.3 ELISA Kit
 MUA2.3 Recombinant
 MUA2.3 Antibody
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DNA repair protein XRCC4

 DNA repair protein XRCC4 ELISA Kit
 DNA repair protein XRCC4 Recombinant
 DNA repair protein XRCC4 Antibody
A. thaliana homologue of the human DNA ligase IV-binding protein XRCC4. Yeast two-hybrid analysis demonstrated a strong interaction between A. thaliana DNA ligase IV and the A. thaliana homologue of the human DNA ligase IV-binding protein XRCC4. This interaction is shown to be mediated via the tandem BRCA C-terminal domains of A. thaliana DNA ligase IV protein.
 XRCC4 ELISA Kit
 XRCC4 Recombinant
 XRCC4 Antibody
 At3g23100 ELISA Kit
 At3g23100 Recombinant
 At3g23100 Antibody
 MXC7.14 ELISA Kit
 MXC7.14 Recombinant
 MXC7.14 Antibody
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DNA repair protein XRS2

 DNA repair protein XRS2 ELISA Kit
 DNA repair protein XRS2 Recombinant
 DNA repair protein XRS2 Antibody
During meiosis is involved in homologous recombination and during vegetative growth it is necessary for DNA repair. It probably regulates the 5'-3' exonuclease degradation of double strand breaks either at the initiation stage or a later stage.
 XRS2 ELISA Kit
 XRS2 Recombinant
 XRS2 Antibody
 YDR369C ELISA Kit
 YDR369C Recombinant
 YDR369C Antibody
 D9481.13 ELISA Kit
 D9481.13 Recombinant
 D9481.13 Antibody
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DNA-repair protein XRCC1

 DNA-repair protein XRCC1 ELISA Kit
 DNA-repair protein XRCC1 Recombinant
 DNA-repair protein XRCC1 Antibody
Also known as DNA-repair protein XRCC1 (AtXRCC1) (Homolog of X-ray repair cross complementing 1).
Encodes a component of plant break excision repair and functions at several stages during active DNA demethylation in Arabidopsis.
 XRCC1 ELISA Kit
 XRCC1 Recombinant
 XRCC1 Antibody
 At1g80420 ELISA Kit
 At1g80420 Recombinant
 At1g80420 Antibody
 T21F11.25 ELISA Kit
 T21F11.25 Recombinant
 T21F11.25 Antibody
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Proteins Root Name Listing
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