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DNA replication factor

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Required for both DNA replication and mitosis .

Below are the list of possible DNA replication factor products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

DNA replication factor Cdt1

 DNA replication factor Cdt1 ELISA Kit
 DNA replication factor Cdt1 Recombinant
 DNA replication factor Cdt1 Antibody
Also known as DNA replication factor Cdt1 (Double parked homolog) (DUP).
CDT1: an essential licensing protein for DNA replication. Cooperates with CDC6 to promote the loading of the mini-chromosome maintenance complex onto chromatin to form the pre-replication complex necessary to initiate DNA replication. Binds DNA in a sequence-, strand-, and conformation-independent manner. Elevated in all h
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uman tumor cell lines analyzed. May function as an oncogene in mammals. Interaction with GMNN inhibits both binding of the MCM complex to origins of replication and DNA-binding activity. Present during G1 and early S phase of the cell cycle. Degraded during the late S, G2, and M phases.

Protein type: DNA replication; DNA-binding; Motility/polarity/chemotaxis; Oncoprotein

Chromosomal Location of Human Ortholog: 16q24.3

Cellular Component: cytosol; nucleoplasm; nucleus

Molecular Function: DNA binding; protein binding

Biological Process: DNA replication checkpoint; G1/S transition of mitotic cell cycle; G1/S-specific transcription in mitotic cell cycle; regulation of DNA replication initiation

Disease: Meier-gorlin Syndrome 4
 CDT1 ELISA Kit
 CDT1 Recombinant
 CDT1 Antibody
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