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DNA replication licensing factor

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Required for DNA synthesis. Required for entry into or completion of S phase. Involved in DNA replication and seems to participate in the activation of the pre-replication complex (pre-RC) and in transcription elongation. May play a role as key coordinator in assembling the replication fork. Proposed to function at replication origins following the binding of the mcm2-7 complex prior to the recruitment of sna41. Probably is required to stimulate phosphorylation of the mcm2-7 complex by the dfp1-hsk1 kinase complex. May recruit the DNA polymerase alpha:primase complex to replication origins and is required to maintain it on chromatin independently of sna41. May have primase activity. Binds to single-stranded DNA.

Below are the list of possible DNA replication licensing factor products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

DNA replication licensing factor mcm10

 DNA replication licensing factor mcm10 ELISA Kit
 DNA replication licensing factor mcm10 Recombinant
 DNA replication licensing factor mcm10 Antibody
Also known as DNA replication licensing factor mcm10 (Cdc23 protein) (Minichromosome maintenance protein 10).
Required for DNA synthesis. Required for entry into or completion of S phase. Involved in DNA replication and seems to participate in the activation of the pre-replication complex (pre-RC) and in transcription elongation. May play a role as key coordinator in assembling the replication fork. Proposed to function at replication origins following the binding of the mcm2-7 complex prior to the recruitment of sna41. Probably is required to stimulate phosphorylation of the mcm2-7 complex
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by the dfp1-hsk1 kinase complex. May recruit the DNA polymerase alpha:primase complex to replication origins and is required to maintain it on chromatin independently of sna41. May have primase activity. Binds to single-stranded DNA.
 mcm10 ELISA Kit
 mcm10 Recombinant
 mcm10 Antibody
 cdc23 ELISA Kit
 cdc23 Recombinant
 cdc23 Antibody
 SPBC1347.10 ELISA Kit
 SPBC1347.10 Recombinant
 SPBC1347.10 Antibody
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DNA replication licensing factor mcm2

 DNA replication licensing factor mcm2 ELISA Kit
 DNA replication licensing factor mcm2 Recombinant
 DNA replication licensing factor mcm2 Antibody
Also known as DNA replication licensing factor mcm2 (BM28-homolog) (Minichromosome maintenance protein 2) (xMCM2) (p112).
Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction s
>>>
urfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for the entry in S phase and for cell division.
 mcm2 ELISA Kit
 mcm2 Recombinant
 mcm2 Antibody
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DNA replication licensing factor MCM3

 DNA replication licensing factor MCM3 ELISA Kit
 DNA replication licensing factor MCM3 Recombinant
 DNA replication licensing factor MCM3 Antibody
Acts as a factor that allows the DNA to undergo a single round of replication per cell cycle. Required for DNA replication and cell proliferation (). May act as a component of the MCM complex which is the putative replicative helicase of the replication licensing system in eukaryotic cells.
 MCM3 ELISA Kit
 MCM3 Recombinant
 MCM3 Antibody
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DNA replication licensing factor MCM3 homolog 1

 DNA replication licensing factor MCM3 homolog 1 ELISA Kit
 DNA replication licensing factor MCM3 homolog 1 Recombinant
 DNA replication licensing factor MCM3 homolog 1 Antibody
Also known as DNA replication licensing factor MCM3 homolog 1 (Replication origin activator 1) (ROA-1).
Acts as a factor that allows the DNA to undergo a single round of replication per cell cycle. Required for DNA replication and cell proliferation (). May act as a component of the MCM complex which is the putative replicative helicase of the replication licensing system in eukaryotic cells.
 ROA1 ELISA Kit
 ROA1 Recombinant
 ROA1 Antibody
 ROA ELISA Kit
 ROA Recombinant
 ROA Antibody
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DNA replication licensing factor MCM3 homolog 2

 DNA replication licensing factor MCM3 homolog 2 ELISA Kit
 DNA replication licensing factor MCM3 homolog 2 Recombinant
 DNA replication licensing factor MCM3 homolog 2 Antibody
Also known as DNA replication licensing factor MCM3 homolog 2 (Replication origin activator 2) (ROA-2).
Acts as a factor that allows the DNA to undergo a single round of replication per cell cycle. Required for DNA replication and cell proliferation (). May act as a component of the MCM complex which is the putative replicative helicase of the replication licensing system in eukaryotic cells.
 ROA2 ELISA Kit
 ROA2 Recombinant
 ROA2 Antibody
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DNA replication licensing factor MCM3 homolog 3

 DNA replication licensing factor MCM3 homolog 3 ELISA Kit
 DNA replication licensing factor MCM3 homolog 3 Recombinant
 DNA replication licensing factor MCM3 homolog 3 Antibody
Also known as DNA replication licensing factor MCM3 homolog 3 (Replication origin activator 3) (ROA-3).
Acts as a factor that allows the DNA to undergo a single round of replication per cell cycle. Required for DNA replication and cell proliferation (). May act as a component of the MCM complex which is the putative replicative helicase of the replication licensing system in eukaryotic cells.
 ROA3 ELISA Kit
 ROA3 Recombinant
 ROA3 Antibody
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DNA replication licensing factor MCM4

 DNA replication licensing factor MCM4 ELISA Kit
 DNA replication licensing factor MCM4 Recombinant
 DNA replication licensing factor MCM4 Antibody
Also known as DNA replication licensing factor MCM4 (CDC21 homolog) (P1-CDC21).
MCM4: a mini-chromosome maintenance protein, essential for the initiation of eukaryotic genome replication. The MCM hexameric protein complex is a key component of the pre-replication complex. The complex consisting of this protein and MCM2, 6 and 7 possesses DNA helicase activity. Phosphorylation by CDC2 reduces th
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e DNA helicase activity and chromatin binding of the complex.

Protein type: DNA replication; EC 3.6.4.12

Chromosomal Location of Human Ortholog: 8q11.2

Cellular Component: MCM complex; membrane; nuclear chromosome, telomeric region; nucleoplasm

Molecular Function: ATP-dependent DNA helicase activity; protein binding

Biological Process: DNA replication; G1/S transition of mitotic cell cycle

Disease: Natural Killer Cell And Glucocorticoid Deficiency With Dna Repair Defect
 MCM4 ELISA Kit
 MCM4 Recombinant
 MCM4 Antibody
 CDC21 ELISA Kit
 CDC21 Recombinant
 CDC21 Antibody
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DNA replication licensing factor mcm4-A

 DNA replication licensing factor mcm4-A ELISA Kit
 DNA replication licensing factor mcm4-A Recombinant
 DNA replication licensing factor mcm4-A Antibody
Also known as DNA replication licensing factor mcm4-A (CDC21 homolog-A) (Minichromosome maintenance protein 4-A) (xMCM4-A) (P1-CDC21-A) (p98).
Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed thro
>>>
ugh the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
 mcm4-a ELISA Kit
 mcm4-a Recombinant
 mcm4-a Antibody
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DNA replication licensing factor mcm4-B

 DNA replication licensing factor mcm4-B ELISA Kit
 DNA replication licensing factor mcm4-B Recombinant
 DNA replication licensing factor mcm4-B Antibody
Also known as DNA replication licensing factor mcm4-B (CDC21 homolog-B) (Minichromosome maintenance protein 4-B) (xMCM4-B) (P1-CDC21-B).
Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through th
>>>
e interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
 mcm4-b ELISA Kit
 mcm4-b Recombinant
 mcm4-b Antibody
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DNA replication licensing factor mcm5

 DNA replication licensing factor mcm5 ELISA Kit
 DNA replication licensing factor mcm5 Recombinant
 DNA replication licensing factor mcm5 Antibody
Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans
>>>
relative to the ATP-binding site of the Walker A box of the adjacent subunit ().
 mcm5 ELISA Kit
 mcm5 Recombinant
 mcm5 Antibody
 DDB_G0292958 ELISA Kit
 DDB_G0292958 Recombinant
 DDB_G0292958 Antibody
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DNA replication licensing factor mcm-5

 DNA replication licensing factor mcm-5 ELISA Kit
 DNA replication licensing factor mcm-5 Recombinant
 DNA replication licensing factor mcm-5 Antibody
Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans
>>>
relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity ().
 mcm-5 ELISA Kit
 mcm-5 Recombinant
 mcm-5 Antibody
 R10E4.4 ELISA Kit
 R10E4.4 Recombinant
 R10E4.4 Antibody
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DNA replication licensing factor mcm5-A

 DNA replication licensing factor mcm5-A ELISA Kit
 DNA replication licensing factor mcm5-A Recombinant
 DNA replication licensing factor mcm5-A Antibody
Also known as DNA replication licensing factor mcm5-A (xMCM5-A) (CDC46 homolog A) (xCDC46-A) (CDC46p) (p92).
Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of tw
>>>
o neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity ().
 mcm5-a ELISA Kit
 mcm5-a Recombinant
 mcm5-a Antibody
 cdc46-a ELISA Kit
 cdc46-a Recombinant
 cdc46-a Antibody
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DNA replication licensing factor mcm5-B

 DNA replication licensing factor mcm5-B ELISA Kit
 DNA replication licensing factor mcm5-B Recombinant
 DNA replication licensing factor mcm5-B Antibody
Also known as DNA replication licensing factor mcm5-B (xMCM5-B) (CDC46 homolog B) (xCDC46-B).
Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring s
>>>
ubunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity ().
 mcm5-b ELISA Kit
 mcm5-b Recombinant
 mcm5-b Antibody
Table BarTOPTable Bar
 

DNA replication licensing factor MCM6

 DNA replication licensing factor MCM6 ELISA Kit
 DNA replication licensing factor MCM6 Recombinant
 DNA replication licensing factor MCM6 Antibody
Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans
>>>
relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
 MCM6 ELISA Kit
 MCM6 Recombinant
 MCM6 Antibody
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DNA replication licensing factor mcm-6

 DNA replication licensing factor mcm-6 ELISA Kit
 DNA replication licensing factor mcm-6 Recombinant
 DNA replication licensing factor mcm-6 Antibody
Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans
>>>
relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity ().
 mcm-6 ELISA Kit
 mcm-6 Recombinant
 mcm-6 Antibody
 ZK632.1 ELISA Kit
 ZK632.1 Recombinant
 ZK632.1 Antibody
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DNA replication licensing factor MCM7

 DNA replication licensing factor MCM7 ELISA Kit
 DNA replication licensing factor MCM7 Recombinant
 DNA replication licensing factor MCM7 Antibody
Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans
>>>
relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for S-phase checkpoint activation upon UV-induced damage ().
 MCM7 ELISA Kit
 MCM7 Recombinant
 MCM7 Antibody
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DNA replication licensing factor mcm7-A

 DNA replication licensing factor mcm7-A ELISA Kit
 DNA replication licensing factor mcm7-A Recombinant
 DNA replication licensing factor mcm7-A Antibody
Also known as DNA replication licensing factor mcm7-A (CDC47 homolog A) (CDC47p) (Minichromosome maintenance protein 7-A) (xMCM7-A) (p90).
Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through
>>>
the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. The existence of maternal and zygotic forms of mcm3 and mcm6 suggests that specific forms of mcm2-7 complexes may be used during different stages of development.
 mcm7-a ELISA Kit
 mcm7-a Recombinant
 mcm7-a Antibody
 cdc47 ELISA Kit
 cdc47 Recombinant
 cdc47 Antibody
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DNA replication licensing factor mcm7-B

 DNA replication licensing factor mcm7-B ELISA Kit
 DNA replication licensing factor mcm7-B Recombinant
 DNA replication licensing factor mcm7-B Antibody
Also known as DNA replication licensing factor mcm7-B (CDC47 homolog B) (CDC47-2p) (Minichromosome maintenance protein 7-B) (xMCM7-B).
Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the
>>>
interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. The existence of maternal and zygotic forms of mcm3 and mcm6 suggests that specific forms of mcm2-7 complexes may be used during different stages of development ().
 mcm7-b ELISA Kit
 mcm7-b Recombinant
 mcm7-b Antibody
 cdc47-2 ELISA Kit
 cdc47-2 Recombinant
 cdc47-2 Antibody
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DNA replication licensing factor REC

 DNA replication licensing factor REC ELISA Kit
 DNA replication licensing factor REC Recombinant
 DNA replication licensing factor REC Antibody
Also known as DNA replication licensing factor REC (Protein mini chromosome maintenance-related) (Protein recombination-defective).
Required for meiotic DNA recombination in females. Probably not involved in DNA repair and recombination in somatic cells.
 rec ELISA Kit
 rec Recombinant
 rec Antibody
 CG31293 ELISA Kit
 CG31293 Recombinant
 CG31293 Antibody
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