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DnaJ homolog subfamily

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Co-chaperone for HSPA8/Hsc70. Plays a role in protein transport into mitochondria via its role as co-chaperone. Functions as co-chaperone for HSPA1B and negatively regulates the translocation of BAX from the cytosol to mitochondria in response to cellular stress, thereby protecting cells against apoptosis. Stimulates ATP hydrolysis, but not the folding of unfolded proteins mediated by HSPA1A (in vitro). Promotes apoptosis in response to cellular stress mediated by exposure to anisomycin or UV (By similarity).

Below are the list of possible DnaJ homolog subfamily products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

DnaJ homolog subfamily A member 1

 DnaJ homolog subfamily A member 1 ELISA Kit
 DnaJ homolog subfamily A member 1 Recombinant
 DnaJ homolog subfamily A member 1 Antibody
Co-chaperone for HSPA8/Hsc70. Plays a role in protein transport into mitochondria via its role as co-chaperone. Functions as co-chaperone for HSPA1B and negatively regulates the translocation of BAX from the cytosol to mitochondria in response to cellular stress, thereby protecting cells against apoptosis. Stimulates ATP hydrolysis, but not the folding of unfolded proteins mediated by HSPA1A (in v
>>>
itro). Promotes apoptosis in response to cellular stress mediated by exposure to anisomycin or UV ().
 DNAJA1 ELISA Kit
 DNAJA1 Recombinant
 DNAJA1 Antibody
Table BarTOPTable Bar
 

DnaJ homolog subfamily A member 1 homolog

 DnaJ homolog subfamily A member 1 homolog ELISA Kit
 DnaJ homolog subfamily A member 1 homolog Recombinant
 DnaJ homolog subfamily A member 1 homolog Antibody
Co-chaperone for Hsp70 family members. Plays a role in protein transport into mitochondria and in the regulation of apoptosis via its role as co-chaperone ().
 dnaja1 ELISA Kit
 dnaja1 Recombinant
 dnaja1 Antibody
 DDB_G0291568 ELISA Kit
 DDB_G0291568 Recombinant
 DDB_G0291568 Antibody
Table BarTOPTable Bar
 

DnaJ homolog subfamily A member 2

 DnaJ homolog subfamily A member 2 ELISA Kit
 DnaJ homolog subfamily A member 2 Recombinant
 DnaJ homolog subfamily A member 2 Antibody
Co-chaperone of Hsc70.
 DNAJA2 ELISA Kit
 DNAJA2 Recombinant
 DNAJA2 Antibody
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DnaJ homolog subfamily A member 3

 DnaJ homolog subfamily A member 3 ELISA Kit
 DnaJ homolog subfamily A member 3 Recombinant
 DnaJ homolog subfamily A member 3 Antibody
Also known as DnaJ homolog subfamily A member 3, mitochondrial (DnaJ protein Tid-1) (hTid-1) (Hepatocellular carcinoma-associated antigen 57) (Tumorous imaginal discs protein Tid56 homolog).
DNAJA3: Modulates apoptotic signal transduction or effector structures within the mitochondrial matrix. Affect cytochrome C release from the mitochondria and caspase 3 activation, but not caspase 8 activation. Isoform 1 increases apoptosis triggered by both TNF and the DNA-damaging agent mytomycin C; in sharp contrast, isoform 2 suppresses apoptosis. Can modulate IFN-gamma- mediated transcriptional acti
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vity. Isoform 2 may play a role in neuromuscular junction development as an effector of the MUSK signaling pathway. Interacts with JAK2, HSPA9B and IFN-gammaR2 chain. Interacts with Ras GTPase-activating protein 1 (RASA1). Isoform 2 interacts with MUSK (via the cytoplasmic domain). Widely expressed with highest levels in heart, liver, lung and skeletal muscles. Also expressed in keratinocytes. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Apoptosis; Cell cycle regulation; Chaperone; Mitochondrial

Chromosomal Location of Human Ortholog: 16p13.3

Cellular Component: actin filament; extrinsic to plasma membrane; intracellular membrane-bound organelle; mitochondrial matrix; mitochondrion; neuromuscular junction; postsynaptic membrane

Molecular Function: protein binding

Biological Process: mitochondrion organization and biogenesis; negative regulation of cell proliferation; negative regulation of transcription from RNA polymerase II promoter
 DNAJA3 ELISA Kit
 DNAJA3 Recombinant
 DNAJA3 Antibody
 HCA57 ELISA Kit
 HCA57 Recombinant
 HCA57 Antibody
 TID1 ELISA Kit
 TID1 Recombinant
 TID1 Antibody
Table BarTOPTable Bar
 

DnaJ homolog subfamily A member 4

 DnaJ homolog subfamily A member 4 ELISA Kit
 DnaJ homolog subfamily A member 4 Recombinant
 DnaJ homolog subfamily A member 4 Antibody
DNAJA4: 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Chaperone

Chromosomal Location of Human Ortholog: 15q25.1

Cellular Component: cytosol; membrane

Molecular Function: chaperone binding; protein binding; unfolded protein binding

Biological Process: protein refolding
 DNAJA4 ELISA Kit
 DNAJA4 Recombinant
 DNAJA4 Antibody
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DnaJ homolog subfamily B member 1

 DnaJ homolog subfamily B member 1 ELISA Kit
 DnaJ homolog subfamily B member 1 Recombinant
 DnaJ homolog subfamily B member 1 Antibody
Interacts with HSP70 and can stimulate its ATPase activity. Stimulates the association between HSC70 and HIP ().
 DNAJB1 ELISA Kit
 DNAJB1 Recombinant
 DNAJB1 Antibody
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DnaJ homolog subfamily B member 11

 DnaJ homolog subfamily B member 11 ELISA Kit
 DnaJ homolog subfamily B member 11 Recombinant
 DnaJ homolog subfamily B member 11 Antibody
Also known as DnaJ homolog subfamily B member 11 (APOBEC1-binding protein 2) (ABBP-2) (DnaJ protein homolog 9) (ER-associated DNAJ) (ER-associated Hsp40 co-chaperone) (Endoplasmic reticulum DNA J domain-containing protein 3) (ER-resident protein ERdj3) (ERdj3) (ERj3p) (HEDJ) (Human DnaJ protein 9) (hDj-9) (PWP1-interacting protein 4).
DNAJB11: Serves as a co-chaperone for HSPA5. Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. May help recruiting HSP
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A5 and other chaperones to the substrate. Stimulates HSPA5 ATPase activity.

Protein type: Chaperone; Endoplasmic reticulum; RNA processing; Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 3q27.3

Cellular Component: endoplasmic reticulum; endoplasmic reticulum lumen; membrane

Molecular Function: protein binding

Biological Process: positive regulation of ATPase activity
 DNAJB11 ELISA Kit
 DNAJB11 Recombinant
 DNAJB11 Antibody
 EDJ ELISA Kit
 EDJ Recombinant
 EDJ Antibody
 ERJ3 ELISA Kit
 ERJ3 Recombinant
 ERJ3 Antibody
 HDJ9 ELISA Kit
 HDJ9 Recombinant
 HDJ9 Antibody
Table BarTOPTable Bar
 

DnaJ homolog subfamily B member 12

 DnaJ homolog subfamily B member 12 ELISA Kit
 DnaJ homolog subfamily B member 12 Recombinant
 DnaJ homolog subfamily B member 12 Antibody
DNAJB12: 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Chaperone; Membrane protein, integral

Chromosomal Location of Human Ortholog: 10q22.1

Cellular Component: membrane
 DNAJB12 ELISA Kit
 DNAJB12 Recombinant
 DNAJB12 Antibody
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DnaJ homolog subfamily B member 13

 DnaJ homolog subfamily B member 13 ELISA Kit
 DnaJ homolog subfamily B member 13 Recombinant
 DnaJ homolog subfamily B member 13 Antibody
Also known as DnaJ homolog subfamily B member 13 (Testis and spermatogenesis cell-related protein 6) (Testis spermatocyte apoptosis-related gene 6 protein) (Testis spermatogenesis apoptosis-related gene 3 protein) (Testis spermatogenesis apoptosis-related gene 6 protein).
DNAJB13: May be involved in inhibiting testis spermatogenesis apoptosis. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Chaperone

Chromosomal Location of Human Ortholog: 11q13.4

Molecular Function: protein binding

Disease: Ciliary Dyskinesia, Primary, 34
 DNAJB13 ELISA Kit
 DNAJB13 Recombinant
 DNAJB13 Antibody
 TSARG3 ELISA Kit
 TSARG3 Recombinant
 TSARG3 Antibody
 TSARG6 ELISA Kit
 TSARG6 Recombinant
 TSARG6 Antibody
Table BarTOPTable Bar
 

DnaJ homolog subfamily B member 14

 DnaJ homolog subfamily B member 14 ELISA Kit
 DnaJ homolog subfamily B member 14 Recombinant
 DnaJ homolog subfamily B member 14 Antibody
DNAJB14: May act as a co-chaperone. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Chaperone; Membrane protein, integral

Cellular Component: membrane
 Dnajb14 ELISA Kit
 Dnajb14 Recombinant
 Dnajb14 Antibody
Table BarTOPTable Bar
 

DnaJ homolog subfamily B member 2

 DnaJ homolog subfamily B member 2 ELISA Kit
 DnaJ homolog subfamily B member 2 Recombinant
 DnaJ homolog subfamily B member 2 Antibody
Also known as DnaJ homolog subfamily B member 2 (DnaJ homolog subfamily B member 10) (mDj8).
DNAJB2: 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Chaperone

Cellular Component: cytosol; nucleus

Molecular Function: chaperone binding; unfolded protein binding

Biological Process: protein refolding
 Dnajb2 ELISA Kit
 Dnajb2 Recombinant
 Dnajb2 Antibody
 Dnajb10 ELISA Kit
 Dnajb10 Recombinant
 Dnajb10 Antibody
Table BarTOPTable Bar
 

DnaJ homolog subfamily B member 3

 DnaJ homolog subfamily B member 3 ELISA Kit
 DnaJ homolog subfamily B member 3 Recombinant
 DnaJ homolog subfamily B member 3 Antibody
DNAJB3: May operate as a co-chaperone of the male germ cell- and haploid stage-specific Hsp70 proteins (Potential).

Protein type: Chaperone

Chromosomal Location of Human Ortholog: 2q37
 DNAJB3 ELISA Kit
 DNAJB3 Recombinant
 DNAJB3 Antibody
 HCG3 ELISA Kit
 HCG3 Recombinant
 HCG3 Antibody
Table BarTOPTable Bar
 

DnaJ homolog subfamily B member 4

 DnaJ homolog subfamily B member 4 ELISA Kit
 DnaJ homolog subfamily B member 4 Recombinant
 DnaJ homolog subfamily B member 4 Antibody
Probable chaperone.
 DNAJB4 ELISA Kit
 DNAJB4 Recombinant
 DNAJB4 Antibody
Table BarTOPTable Bar
 

DnaJ homolog subfamily B member 5

 DnaJ homolog subfamily B member 5 ELISA Kit
 DnaJ homolog subfamily B member 5 Recombinant
 DnaJ homolog subfamily B member 5 Antibody
 DNAJB5 ELISA Kit
 DNAJB5 Recombinant
 DNAJB5 Antibody
Table BarTOPTable Bar
 

DnaJ homolog subfamily B member 6

 DnaJ homolog subfamily B member 6 ELISA Kit
 DnaJ homolog subfamily B member 6 Recombinant
 DnaJ homolog subfamily B member 6 Antibody
Plays an indispensable role in the organization of KRT8/KRT18 filaments. Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin. Suppresses aggregation and toxicity of polyglutamine-containing, aggregation-prone proteins (). Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70.
>>>
Also reduces cellular toxicity and caspase-3 activity ().
 DNAJB6 ELISA Kit
 DNAJB6 Recombinant
 DNAJB6 Antibody
 RCJMB04_4b8 ELISA Kit
 RCJMB04_4b8 Recombinant
 RCJMB04_4b8 Antibody
Table BarTOPTable Bar
 

DnaJ homolog subfamily B member 6-A

 DnaJ homolog subfamily B member 6-A ELISA Kit
 DnaJ homolog subfamily B member 6-A Recombinant
 DnaJ homolog subfamily B member 6-A Antibody
Plays an indispensable role in the organization of krt8/krt18 filaments. Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin. Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70 ().
 dnajb6-a ELISA Kit
 dnajb6-a Recombinant
 dnajb6-a Antibody
Table BarTOPTable Bar
 

DnaJ homolog subfamily B member 6-B

 DnaJ homolog subfamily B member 6-B ELISA Kit
 DnaJ homolog subfamily B member 6-B Recombinant
 DnaJ homolog subfamily B member 6-B Antibody
Plays an indispensable role in the organization of krt8/krt18 filaments. Acts as an endogenous molecular chaperone for neuronal proteins including huntingtin. Has a stimulatory effect on the ATPase activity of HSP70 in a dose-dependent and time-dependent manner and hence acts as a co-chaperone of HSP70 ().
 dnajb6-b ELISA Kit
 dnajb6-b Recombinant
 dnajb6-b Antibody
Table BarTOPTable Bar
 

DnaJ homolog subfamily B member 7

 DnaJ homolog subfamily B member 7 ELISA Kit
 DnaJ homolog subfamily B member 7 Recombinant
 DnaJ homolog subfamily B member 7 Antibody
DNAJB7: Probably acts as a co-chaperone.

Protein type: Chaperone

Chromosomal Location of Human Ortholog: 22q13.2

Molecular Function: chaperone binding
 DNAJB7 ELISA Kit
 DNAJB7 Recombinant
 DNAJB7 Antibody
 HSC3 ELISA Kit
 HSC3 Recombinant
 HSC3 Antibody
Table BarTOPTable Bar
 

DnaJ homolog subfamily B member 8

 DnaJ homolog subfamily B member 8 ELISA Kit
 DnaJ homolog subfamily B member 8 Recombinant
 DnaJ homolog subfamily B member 8 Antibody
DNAJB8: Efficient suppressor of aggregation and toxicity of disease-associated polyglutamine proteins.

Protein type: Chaperone

Chromosomal Location of Human Ortholog: 3q21.3

Cellular Component: cytosol; nucleus

Molecular Function: chaperone binding; unfolded protein binding
 DNAJB8 ELISA Kit
 DNAJB8 Recombinant
 DNAJB8 Antibody
Table BarTOPTable Bar
 

DnaJ homolog subfamily B member 9

 DnaJ homolog subfamily B member 9 ELISA Kit
 DnaJ homolog subfamily B member 9 Recombinant
 DnaJ homolog subfamily B member 9 Antibody
Involved in endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins. Acts as a co-chaperone with an Hsp70 protein ().
 DNAJB9 ELISA Kit
 DNAJB9 Recombinant
 DNAJB9 Antibody
Table BarTOPTable Bar
 

DnaJ homolog subfamily C GRV2

 DnaJ homolog subfamily C GRV2 ELISA Kit
 DnaJ homolog subfamily C GRV2 Recombinant
 DnaJ homolog subfamily C GRV2 Antibody
Also known as DnaJ homolog subfamily C GRV2 (Protein GRAVITROPISM DEFECTIVE 2) (Protein GREEN FLUORESCENT SEED 2) (Protein KATAMARI2).
GRV2 has sequence similarity to the C. elegans protein RME-8 which is involved in endocytosis. grv2 mutants result in a reduction in gravitropic response in hypocotyls and shoots but do not affect root gravitropism. The mutants are defective in amyloplast sedimentation.
 GRV2 ELISA Kit
 GRV2 Recombinant
 GRV2 Antibody
 GFS2 ELISA Kit
 GFS2 Recombinant
 GFS2 Antibody
 KAM2 ELISA Kit
 KAM2 Recombinant
 KAM2 Antibody
 At2g26890 ELISA Kit
 At2g26890 Recombinant
 At2g26890 Antibody
Table BarTOPTable Bar
 

DnaJ homolog subfamily C member 1

 DnaJ homolog subfamily C member 1 ELISA Kit
 DnaJ homolog subfamily C member 1 Recombinant
 DnaJ homolog subfamily C member 1 Antibody
Also known as DnaJ homolog subfamily C member 1 (DnaJ protein homolog MTJ1).
 DNAJC1 ELISA Kit
 DNAJC1 Recombinant
 DNAJC1 Antibody
Table BarTOPTable Bar
 

DnaJ homolog subfamily C member 10

 DnaJ homolog subfamily C member 10 ELISA Kit
 DnaJ homolog subfamily C member 10 Recombinant
 DnaJ homolog subfamily C member 10 Antibody
Endoplasmic reticulum disulfide reductase involved both in the correct folding of proteins and degradation of misfolded proteins. Required for efficient folding of proteins in the endoplasmic reticulum by catalyzing the removal of non-native disulfide bonds formed during the folding of proteins, such as LDLR. Also involved in endoplasmic reticulum-associated degradation (ERAD) by reducing incorrec
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t disulfide bonds in misfolded glycoproteins recognized by EDEM1. Interaction with HSPA5 is required its activity, not for the disulfide reductase activity, but to facilitate the release of DNAJC10 from its substrate. Promotes apoptotic signaling pathway in response to endoplasmic reticulum stress ().
 DNAJC10 ELISA Kit
 DNAJC10 Recombinant
 DNAJC10 Antibody
Table BarTOPTable Bar
 

DnaJ homolog subfamily C member 11

 DnaJ homolog subfamily C member 11 ELISA Kit
 DnaJ homolog subfamily C member 11 Recombinant
 DnaJ homolog subfamily C member 11 Antibody
DNAJC11: Belongs to the DNAJC11 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Chaperone; Mitochondrial

Cellular Component: mitochondrial inner membrane; mitochondrion
 Dnajc11 ELISA Kit
 Dnajc11 Recombinant
 Dnajc11 Antibody
Table BarTOPTable Bar
 

DnaJ homolog subfamily C member 11 homolog

 DnaJ homolog subfamily C member 11 homolog ELISA Kit
 DnaJ homolog subfamily C member 11 homolog Recombinant
 DnaJ homolog subfamily C member 11 homolog Antibody
 dnajc11 ELISA Kit
 dnajc11 Recombinant
 dnajc11 Antibody
 DDB_G0284263 ELISA Kit
 DDB_G0284263 Recombinant
 DDB_G0284263 Antibody
Table BarTOPTable Bar
 

DnaJ homolog subfamily C member 12

 DnaJ homolog subfamily C member 12 ELISA Kit
 DnaJ homolog subfamily C member 12 Recombinant
 DnaJ homolog subfamily C member 12 Antibody
Also known as DnaJ homolog subfamily C member 12 (J domain-containing protein 1).
 Dnajc12 ELISA Kit
 Dnajc12 Recombinant
 Dnajc12 Antibody
 Jdp1 ELISA Kit
 Jdp1 Recombinant
 Jdp1 Antibody
Table BarTOPTable Bar
 

DnaJ homolog subfamily C member 13

 DnaJ homolog subfamily C member 13 ELISA Kit
 DnaJ homolog subfamily C member 13 Recombinant
 DnaJ homolog subfamily C member 13 Antibody
Also known as DnaJ homolog subfamily C member 13 (Required for receptor-mediated endocytosis 8) (RME-8).
DNAJC13: Involved in membrane trafficking through early endosomes, such as the early endosome to recycling endosome transport implicated in the recycling of transferrin and the early endosome to late endosome transport implicated in degradation of EGF and EGFR (PubMed:18256511, PubMed:18307993). Involved in the regulation of endosomal membrane tubulation and regulates th dynamics of SNX1 on the endosomal membrane; via association with FAM21 may link the WASH complex to the retromer SNX-B
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AR subcomplex (PubMed:24643499). {ECO:0000269|PubMed:18256511, ECO:0000269|PubMed:18307993, ECO:0000269|PubMed:24643499}. Interacts with FAM21C; mediates the association with the WASH complex (PubMed:24643499). {ECO:0000269|PubMed:24643499}

Protein type: Chaperone

Chromosomal Location of Human Ortholog: 3q22.1

Cellular Component: cytoplasm; early endosome membrane; endosome membrane; intracellular membrane-bound organelle; lysosomal membrane; membrane

Molecular Function: protein binding

Biological Process: endosome organization and biogenesis; osteoblast differentiation

Disease: Parkinson Disease 21
 DNAJC13 ELISA Kit
 DNAJC13 Recombinant
 DNAJC13 Antibody
 KIAA0678 ELISA Kit
 KIAA0678 Recombinant
 KIAA0678 Antibody
 RME8 ELISA Kit
 RME8 Recombinant
 RME8 Antibody
Table BarTOPTable Bar
 

DnaJ homolog subfamily C member 14

 DnaJ homolog subfamily C member 14 ELISA Kit
 DnaJ homolog subfamily C member 14 Recombinant
 DnaJ homolog subfamily C member 14 Antibody
DNAJC14: Regulates the export of target proteins, such as DRD1, from the endoplasmic reticulum to the cell surface.

Protein type: Chaperone; Endoplasmic reticulum; Membrane protein, integral; Membrane protein, multi-pass

Cellular Component: membrane; nucleolus; nucleoplasm

Molecular Function: dopamine receptor binding; G-protein-coupled receptor binding
 Dnajc14 ELISA Kit
 Dnajc14 Recombinant
 Dnajc14 Antibody
Table BarTOPTable Bar
 

DnaJ homolog subfamily C member 15

 DnaJ homolog subfamily C member 15 ELISA Kit
 DnaJ homolog subfamily C member 15 Recombinant
 DnaJ homolog subfamily C member 15 Antibody
Negative regulator of the mitochondrial respiratory chain. Prevents mitochondrial hyperpolarization state and restricts mitochondrial generation of ATP. Acts as an import component of the TIM23 translocase complex. Stimulates the ATPase activity of HSPA9 ().
 DNAJC15 ELISA Kit
 DNAJC15 Recombinant
 DNAJC15 Antibody
Table BarTOPTable Bar
 

DnaJ homolog subfamily C member 16

 DnaJ homolog subfamily C member 16 ELISA Kit
 DnaJ homolog subfamily C member 16 Recombinant
 DnaJ homolog subfamily C member 16 Antibody
DNAJC16: 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Chaperone; Membrane protein, integral

Chromosomal Location of Human Ortholog: 1p36.1
 DNAJC16 ELISA Kit
 DNAJC16 Recombinant
 DNAJC16 Antibody
 KIAA0962 ELISA Kit
 KIAA0962 Recombinant
 KIAA0962 Antibody
Table BarTOPTable Bar
 

DnaJ homolog subfamily C member 17

 DnaJ homolog subfamily C member 17 ELISA Kit
 DnaJ homolog subfamily C member 17 Recombinant
 DnaJ homolog subfamily C member 17 Antibody
May negatively affect PAX8-induced thyroglobulin/TG transcription.
 DNAJC17 ELISA Kit
 DNAJC17 Recombinant
 DNAJC17 Antibody
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DnaJ homolog subfamily C member 18

 DnaJ homolog subfamily C member 18 ELISA Kit
 DnaJ homolog subfamily C member 18 Recombinant
 DnaJ homolog subfamily C member 18 Antibody
DNAJC18:

Protein type: Chaperone; Membrane protein, integral

Chromosomal Location of Human Ortholog: 5q31.2
 DNAJC18 ELISA Kit
 DNAJC18 Recombinant
 DNAJC18 Antibody
Table BarTOPTable Bar
 

DnaJ homolog subfamily C member 2

 DnaJ homolog subfamily C member 2 ELISA Kit
 DnaJ homolog subfamily C member 2 Recombinant
 DnaJ homolog subfamily C member 2 Antibody
Acts both as a chaperone in the cytosol and as a chromatin regulator in the nucleus. When cytosolic, acts as a molecular chaperone: component of the ribosome-associated complex (RAC), a complex involved in folding or maintaining nascent polypeptides in a folding-competent state. When nuclear, mediates the switching from polycomb-repressed genes to an active state: specifically recruited at histone
>>>
H2A ubiquitinated at 'Lys-119' (H2AK119ub), and promotes the displacement of the polycomb PRC1 complex from chromatin, thereby facilitating transcription activation ().
 dnajc2 ELISA Kit
 dnajc2 Recombinant
 dnajc2 Antibody
Table BarTOPTable Bar
 

DnaJ homolog subfamily C member 21

 DnaJ homolog subfamily C member 21 ELISA Kit
 DnaJ homolog subfamily C member 21 Recombinant
 DnaJ homolog subfamily C member 21 Antibody
May act as a co-chaperone for HSP70. May play a role in ribosomal RNA (rRNA) biogenesis, possibly in the maturation of the 60S subunit. Binds the precursor 45S rRNA.
 DNAJC21 ELISA Kit
 DNAJC21 Recombinant
 DNAJC21 Antibody
Table BarTOPTable Bar
 

DnaJ homolog subfamily C member 22

 DnaJ homolog subfamily C member 22 ELISA Kit
 DnaJ homolog subfamily C member 22 Recombinant
 DnaJ homolog subfamily C member 22 Antibody
May function as a co-chaperone.
 DNAJC22 ELISA Kit
 DNAJC22 Recombinant
 DNAJC22 Antibody
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DnaJ homolog subfamily C member 24

 DnaJ homolog subfamily C member 24 ELISA Kit
 DnaJ homolog subfamily C member 24 Recombinant
 DnaJ homolog subfamily C member 24 Antibody
Also known as DnaJ homolog subfamily C member 24 (CSL-type zinc finger-containing protein 3) (Diphthamide biosynthesis protein 4).
Stimulates the ATPase activity of several Hsp70-type chaperones. This ability is enhanced by iron-binding. The iron-bound form is redox-active and can function as electron carrier. Plays a role in the diphthamide biosynthesis, a post-translational modification of histidine which occurs in translation elongation factor 2 (EEF2) ().
 DNAJC24 ELISA Kit
 DNAJC24 Recombinant
 DNAJC24 Antibody
 DPH4 ELISA Kit
 DPH4 Recombinant
 DPH4 Antibody
 ZCSL3 ELISA Kit
 ZCSL3 Recombinant
 ZCSL3 Antibody
Table BarTOPTable Bar
 

DnaJ homolog subfamily C member 25

 DnaJ homolog subfamily C member 25 ELISA Kit
 DnaJ homolog subfamily C member 25 Recombinant
 DnaJ homolog subfamily C member 25 Antibody
DNAJC25: Belongs to the DNAJC25 family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Chaperone; Membrane protein, integral; Membrane protein, multi-pass
 Dnajc25 ELISA Kit
 Dnajc25 Recombinant
 Dnajc25 Antibody
Table BarTOPTable Bar
 

DnaJ homolog subfamily C member 25 homolog

 DnaJ homolog subfamily C member 25 homolog ELISA Kit
 DnaJ homolog subfamily C member 25 homolog Recombinant
 DnaJ homolog subfamily C member 25 homolog Antibody
 CG7872 ELISA Kit
 CG7872 Recombinant
 CG7872 Antibody
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DnaJ homolog subfamily C member 27

 DnaJ homolog subfamily C member 27 ELISA Kit
 DnaJ homolog subfamily C member 27 Recombinant
 DnaJ homolog subfamily C member 27 Antibody
Also known as DnaJ homolog subfamily C member 27 (Rab and DnaJ domain-containing protein).
GTPase possibly involved in regulation of the MEK/ERK pathway.
 dnajc27 ELISA Kit
 dnajc27 Recombinant
 dnajc27 Antibody
 rbj ELISA Kit
 rbj Recombinant
 rbj Antibody
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DnaJ homolog subfamily C member 27-A

 DnaJ homolog subfamily C member 27-A ELISA Kit
 DnaJ homolog subfamily C member 27-A Recombinant
 DnaJ homolog subfamily C member 27-A Antibody
Also known as DnaJ homolog subfamily C member 27-A (Rab and DnaJ domain-containing protein 1) (Rab and DnaJ domain-containing protein A).
GTPase possibly involved in regulation of the MEK/ERK pathway.
 dnajc27-a ELISA Kit
 dnajc27-a Recombinant
 dnajc27-a Antibody
 rbj-a ELISA Kit
 rbj-a Recombinant
 rbj-a Antibody
 rbj1 ELISA Kit
 rbj1 Recombinant
 rbj1 Antibody
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DnaJ homolog subfamily C member 27-B

 DnaJ homolog subfamily C member 27-B ELISA Kit
 DnaJ homolog subfamily C member 27-B Recombinant
 DnaJ homolog subfamily C member 27-B Antibody
Also known as DnaJ homolog subfamily C member 27-B (Rab and DnaJ domain-containing protein 2) (Rab and DnaJ domain-containing protein B).
GTPase possibly involved in regulation of the MEK/ERK pathway.
 dnajc27-b ELISA Kit
 dnajc27-b Recombinant
 dnajc27-b Antibody
 rbj2 ELISA Kit
 rbj2 Recombinant
 rbj2 Antibody
 rjb-b ELISA Kit
 rjb-b Recombinant
 rjb-b Antibody
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DnaJ homolog subfamily C member 28

 DnaJ homolog subfamily C member 28 ELISA Kit
 DnaJ homolog subfamily C member 28 Recombinant
 DnaJ homolog subfamily C member 28 Antibody
DNAJC28: May have a role in protein folding or as a chaperone.

Protein type: Unknown function

Cellular Component: Golgi transport complex

Biological Process: Golgi organization and biogenesis; Golgi vesicle prefusion complex stabilization; retrograde transport, vesicle recycling within Golgi; retrograde vesicle-mediated transport, Golgi to ER
 Dnajc28 ELISA Kit
 Dnajc28 Recombinant
 Dnajc28 Antibody
 ORF28 ELISA Kit
 ORF28 Recombinant
 ORF28 Antibody
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DnaJ homolog subfamily C member 3

 DnaJ homolog subfamily C member 3 ELISA Kit
 DnaJ homolog subfamily C member 3 Recombinant
 DnaJ homolog subfamily C member 3 Antibody
May be involved in the unfolded protein response (UPR) during ER stress.
 DNAJC3 ELISA Kit
 DNAJC3 Recombinant
 DNAJC3 Antibody
 RCJMB04_31h14 ELISA Kit
 RCJMB04_31h14 Recombinant
 RCJMB04_31h14 Antibody
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DnaJ homolog subfamily C member 3 homolog

 DnaJ homolog subfamily C member 3 homolog ELISA Kit
 DnaJ homolog subfamily C member 3 homolog Recombinant
 DnaJ homolog subfamily C member 3 homolog Antibody
May be involved in the unfolded protein response (UPR) during ER stress.
 dnajc3 ELISA Kit
 dnajc3 Recombinant
 dnajc3 Antibody
 DDB_G0286251 ELISA Kit
 DDB_G0286251 Recombinant
 DDB_G0286251 Antibody
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DnaJ homolog subfamily C member 30

 DnaJ homolog subfamily C member 30 ELISA Kit
 DnaJ homolog subfamily C member 30 Recombinant
 DnaJ homolog subfamily C member 30 Antibody
Also known as DnaJ homolog subfamily C member 30 (Williams-Beuren syndrome chromosomal region 18 protein homolog).
DNAJC30: DNAJC30 is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking
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the deleted region.

Protein type: Chaperone; Mitochondrial

Cellular Component: mitochondrion
 Dnajc30 ELISA Kit
 Dnajc30 Recombinant
 Dnajc30 Antibody
 Wbscr18 ELISA Kit
 Wbscr18 Recombinant
 Wbscr18 Antibody
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DnaJ homolog subfamily C member 4

 DnaJ homolog subfamily C member 4 ELISA Kit
 DnaJ homolog subfamily C member 4 Recombinant
 DnaJ homolog subfamily C member 4 Antibody
Also known as DnaJ homolog subfamily C member 4 (DnaJ-like protein HSPF2) (Multiple endocrine neoplasia type 1 candidate protein number 18).
DNAJC4:

Protein type: Chaperone; Membrane protein, integral; Mitochondrial

Chromosomal Location of Human Ortholog: 11q13

Molecular Function: protein binding

Biological Process: response to unfolded protein
 DNAJC4 ELISA Kit
 DNAJC4 Recombinant
 DNAJC4 Antibody
 HSPF2 ELISA Kit
 HSPF2 Recombinant
 HSPF2 Antibody
 MCG18 ELISA Kit
 MCG18 Recombinant
 MCG18 Antibody
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DnaJ homolog subfamily C member 5

 DnaJ homolog subfamily C member 5 ELISA Kit
 DnaJ homolog subfamily C member 5 Recombinant
 DnaJ homolog subfamily C member 5 Antibody
Also known as DnaJ homolog subfamily C member 5 (CCCS1) (Cysteine string protein) (CSP).
May have an important role in presynaptic function. May be involved in calcium-dependent neurotransmitter release at nerve endings.
 dnajc5 ELISA Kit
 dnajc5 Recombinant
 dnajc5 Antibody
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DnaJ homolog subfamily C member 5 homolog

 DnaJ homolog subfamily C member 5 homolog ELISA Kit
 DnaJ homolog subfamily C member 5 homolog Recombinant
 DnaJ homolog subfamily C member 5 homolog Antibody
Also known as DnaJ homolog subfamily C member 5 homolog (Cysteine string protein).
May have an important role in presynaptic function.
 Csp ELISA Kit
 Csp Recombinant
 Csp Antibody
 CG6395 ELISA Kit
 CG6395 Recombinant
 CG6395 Antibody
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DnaJ homolog subfamily C member 5B

 DnaJ homolog subfamily C member 5B ELISA Kit
 DnaJ homolog subfamily C member 5B Recombinant
 DnaJ homolog subfamily C member 5B Antibody
Also known as DnaJ homolog subfamily C member 5B (Cysteine string protein beta) (CSP-beta).
 DNAJC5B ELISA Kit
 DNAJC5B Recombinant
 DNAJC5B Antibody
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DnaJ homolog subfamily C member 5G

 DnaJ homolog subfamily C member 5G ELISA Kit
 DnaJ homolog subfamily C member 5G Recombinant
 DnaJ homolog subfamily C member 5G Antibody
Also known as DnaJ homolog subfamily C member 5G (Cysteine string protein-gamma) (CSP-gamma).
DNAJC5G: 2 isoforms of the human protein are produced by alternative splicing

Protein type: Chaperone

Chromosomal Location of Human Ortholog: 2p23.3
 DNAJC5G ELISA Kit
 DNAJC5G Recombinant
 DNAJC5G Antibody
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DnaJ homolog subfamily C member 7

 DnaJ homolog subfamily C member 7 ELISA Kit
 DnaJ homolog subfamily C member 7 Recombinant
 DnaJ homolog subfamily C member 7 Antibody
Acts as co-chaperone regulating the molecular chaperones HSP70 and HSP90 in folding of steroid receptors, such as the glucocorticoid receptor and the progesterone receptor. Proposed to act as a recycling chaperone by facilitating the return of chaperone substrates to early stages of chaperoning if further folding is required. In vitro, induces ATP-independent dissociation of HSP90 but not of HSP70
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from the chaperone-substrate complexes. Recruits NR1I3 to the cytoplasm ().
 DNAJC7 ELISA Kit
 DNAJC7 Recombinant
 DNAJC7 Antibody
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DnaJ homolog subfamily C member 7 homolog

 DnaJ homolog subfamily C member 7 homolog ELISA Kit
 DnaJ homolog subfamily C member 7 homolog Recombinant
 DnaJ homolog subfamily C member 7 homolog Antibody
 dnajc7 ELISA Kit
 dnajc7 Recombinant
 dnajc7 Antibody
 DDB_G0288639 ELISA Kit
 DDB_G0288639 Recombinant
 DDB_G0288639 Antibody
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DnaJ homolog subfamily C member 8

 DnaJ homolog subfamily C member 8 ELISA Kit
 DnaJ homolog subfamily C member 8 Recombinant
 DnaJ homolog subfamily C member 8 Antibody
DNAJC8:

Protein type: Chaperone; RNA processing; RNA splicing; Spliceosome

Cellular Component: cytoplasm; intercellular bridge; nucleoplasm
 Dnajc8 ELISA Kit
 Dnajc8 Recombinant
 Dnajc8 Antibody
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DnaJ homolog subfamily C member 9

 DnaJ homolog subfamily C member 9 ELISA Kit
 DnaJ homolog subfamily C member 9 Recombinant
 DnaJ homolog subfamily C member 9 Antibody
DNAJC9: May play a role as co-chaperone of the Hsp70 family proteins HSPA1A, HSPA1B and HSPA8. {ECO:0000269|PubMed:17182002}. Induced by heat shock, bacterial lipopolysaccharides (LPS), phorbol 12-myristate 13-acetate (PMA), and the cytokine TNF (at protein level). {ECO:0000269|PubMed:17182002}. Interacts (via J domain) with HSPA1A, HSPA1B and HSPA8. {ECO:0000269|PubMed:17182002}

Protein ty
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pe: Chaperone

Cellular Component: cytoplasm; extracellular space; nucleus; plasma membrane

Molecular Function: heat shock protein binding

Biological Process: positive regulation of ATPase activity
 Dnajc9 ELISA Kit
 Dnajc9 Recombinant
 Dnajc9 Antibody
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Proteins Root Name Listing
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