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Down syndrome cell adhesion molecule

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Cell adhesion molecule that plays a role in neuronal self-avoidance. Promotes repulsion between specific neuronal processes of either the same cell or the same subtype of cells. Mediates within retinal amacrine and ganglion cell subtypes both isoneuronal self-avoidance for creating an orderly dendritic arborization and heteroneuronal self-avoidance to maintain the mosaic spacing between amacrine and ganglion cell bodies .

Below are the list of possible Down syndrome cell adhesion molecule products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Down syndrome cell adhesion molecule

 Down syndrome cell adhesion molecule ELISA Kit
 Down syndrome cell adhesion molecule Recombinant
 Down syndrome cell adhesion molecule Antibody
Also known as Down syndrome cell adhesion molecule (CHD2).
DSCAM: Cell adhesion molecule that plays a role in neuronal self-avoidance. Promotes repulsion between specific neuronal processes of either the same cell or the same subtype of cells. Mediates within retinal amacrine and ganglion cell subtypes both isoneuronal self-avoidance for creating an orderly dendritic arborization and heteroneur
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onal self-avoidance to maintain the mosaic spacing between amacrine and ganglion cell bodies. Receptor for netrin required for axon guidance independently of and in collaboration with the receptor DCC. In spinal chord development plays a role in guiding commissural axons projection and pathfinding across the ventral midline to reach the floor plate upon ligand binding. Enhances netrin-induced phosphorylation of PAK1 and FYN. Mediates intracellular signaling by stimulating the activation of MAPK8 and MAP kinase p38. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Cell adhesion; Membrane protein, integral

Chromosomal Location of Human Ortholog: 21q22.2

Cellular Component: axon; growth cone; membrane; plasma membrane; synapse

Molecular Function: protein binding

Biological Process: cell adhesion; homophilic cell adhesion; negative regulation of cell adhesion; nervous system development; positive regulation of axon extension involved in axon guidance; positive regulation of phosphorylation; synaptogenesis
 DSCAM ELISA Kit
 DSCAM Recombinant
 DSCAM Antibody
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Down syndrome cell adhesion molecule homolog

 Down syndrome cell adhesion molecule homolog ELISA Kit
 Down syndrome cell adhesion molecule homolog Recombinant
 Down syndrome cell adhesion molecule homolog Antibody
Cell adhesion molecule that plays a role in neuronal self-avoidance. Promotes repulsion between specific neuronal processes of either the same cell or the same subtype of cells. Mediates within retinal amacrine and ganglion cell subtypes both isoneuronal self-avoidance for creating an orderly dendritic arborization and heteroneuronal self-avoidance to maintain the mosaic spacing between amacrine a
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nd ganglion cell bodies (). Receptor for netrin required for axon guidance independently of and in collaboration with the receptor DCC (). Adhesion molecule that promotes lamina-specific synaptic connections in the retina: expressed in specific subsets of interneurons and retinal ganglion cells (RGCs) and promotes synaptic connectivity via homophilic interactions (PubMed:18216854).
 DSCAM ELISA Kit
 DSCAM Recombinant
 DSCAM Antibody
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