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Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase

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Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides cAMP and cGMP. Catalyzes the hydrolysis of both cAMP and cGMP to 5'-AMP and 5'-GMP, respectively.

Below are the list of possible Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11

 Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11 ELISA Kit
 Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11 Recombinant
 Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11 Antibody
Also known as Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11 (cAMP and cGMP phosphodiesterase 11).
Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides cAMP and cGMP. Catalyzes the hydrolysis of both cAMP and cGMP to 5'-AMP and 5'-GMP, respectively.
 Pde11 ELISA Kit
 Pde11 Recombinant
 Pde11 Antibody
 CG34341 ELISA Kit
 CG34341 Recombinant
 CG34341 Antibody
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Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A

 Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A ELISA Kit
 Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A Recombinant
 Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A Antibody
Also known as Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A (cAMP and cGMP phosphodiesterase 11A).
PDE11A: Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides cAMP and cGMP. Catalyzes the hydrolysis of both cAMP and cGMP to 5'-AMP and 5'- GMP, respectively. Defects in PDE11A are the cause of primary pigmented nodular adrenocortical dise
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ase type 2 (PPNAD2). Primary pigmented nodular adrenocortical disease is a rare bilateral adrenal defect causing ACTH-independent Cushing syndrome. PPNAD2 is characterized by adrenal glands with overall normal size and weight, and multiple small yellow-to-dark brown nodules surrounded by a cortex with a uniform appearance. Microscopically, there are moderate diffuse cortical hyperplasia with mostly nonpigmented nodules, multiple capsular deficits and massive circumscribed and infiltrating extra-adrenal cortical excrescences with micronodules. PPNAD2 leads to Cushing syndrome. Belongs to the cyclic nucleotide phosphodiesterase family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.1.4.17; EC 3.1.4.35; Mitochondrial; Nucleotide Metabolism - purine; Phosphodiesterase

Chromosomal Location of Human Ortholog: 2q31.2

Cellular Component: cytosol

Molecular Function: 3',5'-cyclic-AMP phosphodiesterase activity; 3',5'-cyclic-GMP phosphodiesterase activity; 3',5'-cyclic-nucleotide phosphodiesterase activity; cGMP binding; cGMP-stimulated cyclic-nucleotide phosphodiesterase activity

Disease: Pigmented Nodular Adrenocortical Disease, Primary, 2
 PDE11A ELISA Kit
 PDE11A Recombinant
 PDE11A Antibody
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