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Dual specificity protein kinase

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Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates: SRSF1, SRSF3 and PTPN1. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells and adenovirus E1A pre-mRNA.

Below are the list of possible Dual specificity protein kinase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Dual specificity protein kinase CLK1

 Dual specificity protein kinase CLK1 ELISA Kit
 Dual specificity protein kinase CLK1 Recombinant
 Dual specificity protein kinase CLK1 Antibody
Also known as Dual specificity protein kinase CLK1 (CDC-like kinase 1).
This gene encodes a member of the CDC2-like (or LAMMER) family of dual specificity protein kinases. In the nucleus, the encoded protein phosphorylates serine/arginine-rich proteins involved in pre-mRNA processing, releasing them into the nucleoplasm. The choice of splice sites during pre-mRNA processing may be regulated by
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the concentration of transacting factors, including serine/arginine rich proteins. Therefore, the encoded protein may play an indirect role in governing splice site selection. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2009]
 CLK1 ELISA Kit
 CLK1 Recombinant
 CLK1 Antibody
 CLK ELISA Kit
 CLK Recombinant
 CLK Antibody
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Dual specificity protein kinase CLK2

 Dual specificity protein kinase CLK2 ELISA Kit
 Dual specificity protein kinase CLK2 Recombinant
 Dual specificity protein kinase CLK2 Antibody
Also known as Dual specificity protein kinase CLK2 (CDC-like kinase 2).
CLK2: Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing and can cause redistribution of SR p
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roteins from speckles to a diffuse nucleoplasmic distribution. Acts as a suppressor of hepatic gluconeogenesis and glucose output by repressing PPARGC1A transcriptional activity on gluconeogenic genes via its phosphorylation. Phosphorylates PPP2R5B thereby stimulating the assembly of PP2A phosphatase with the PPP2R5B-AKT1 complex leading to dephosphorylation of AKT1. Phosphorylates: PTPN1, SRSF1 and SRSF3. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells. Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. Lammer subfamily. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: CLK family; CMGC group; EC 2.7.12.1; Kinase, protein; Protein kinase, CMGC; Protein kinase, dual-specificity (non-receptor)

Chromosomal Location of Human Ortholog: 1q21

Cellular Component: nucleoplasm; nucleus

Molecular Function: identical protein binding; protein binding; protein serine/threonine kinase activity

Biological Process: negative regulation of gluconeogenesis; protein amino acid autophosphorylation; protein amino acid phosphorylation; regulation of RNA splicing; response to ionizing radiation
 CLK2 ELISA Kit
 CLK2 Recombinant
 CLK2 Antibody
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Dual specificity protein kinase CLK3

 Dual specificity protein kinase CLK3 ELISA Kit
 Dual specificity protein kinase CLK3 Recombinant
 Dual specificity protein kinase CLK3 Antibody
Also known as Dual specificity protein kinase CLK3 (CDC-like kinase 3).
CLK3: a CMGC kinase of the CLK family. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex. May play a role in regulating RNA splicing. Three alternatively spliced isoforms have been described. Isoform 2 is short and lacks the kinase domain. May be produced at very low levels due to a prematur
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e stop codon in the mRNA, leading to nonsense-mediated mRNA decay.

Protein type: CLK family; CMGC group; EC 2.7.12.1; Kinase, protein; Protein kinase, CMGC; Protein kinase, dual-specificity (non-receptor)

Cellular Component: intermediate filament cytoskeleton; membrane; nucleoplasm; nucleus

Molecular Function: kinase activity; protein kinase activity; protein serine/threonine kinase activity; protein-tyrosine kinase activity

Biological Process: peptidyl-tyrosine phosphorylation; protein amino acid autophosphorylation; protein amino acid phosphorylation; regulation of RNA splicing
 Clk3 ELISA Kit
 Clk3 Recombinant
 Clk3 Antibody
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Dual specificity protein kinase CLK4

 Dual specificity protein kinase CLK4 ELISA Kit
 Dual specificity protein kinase CLK4 Recombinant
 Dual specificity protein kinase CLK4 Antibody
Also known as Dual specificity protein kinase CLK4 (CDC-like kinase 4).
CLK4: a CMGC kinase of the CLK family. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. It has been reported to regulate splicing of genes such as Tau exon 10 in the mammalian ner
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vous system. Expressed in liver, kidney, heart, muscle and brain. Clk4 mRNAs were expressed in the hippocampus, the cerebellum, and the olfactory bulb.

Protein type: CLK family; CMGC group; EC 2.7.12.1; Kinase, protein; Protein kinase, CMGC; Protein kinase, dual-specificity (non-receptor)

Cellular Component: nucleus

Molecular Function: protein serine/threonine kinase activity; protein-tyrosine kinase activity

Biological Process: peptidyl-tyrosine phosphorylation; protein amino acid autophosphorylation; regulation of RNA splicing
 Clk4 ELISA Kit
 Clk4 Recombinant
 Clk4 Antibody
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Dual specificity protein kinase FUZ7

 Dual specificity protein kinase FUZ7 ELISA Kit
 Dual specificity protein kinase FUZ7 Recombinant
 Dual specificity protein kinase FUZ7 Antibody
Protein kinase that is necessary for a-locus-dependent processes, such as conjugation tube formation, filament formation, and maintenance of filamentous growth, and for a-locus-independent processes, such as tumor induction and teliospore germination.
 FUZ7 ELISA Kit
 FUZ7 Recombinant
 FUZ7 Antibody
 UMAG_01514 ELISA Kit
 UMAG_01514 Recombinant
 UMAG_01514 Antibody
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Dual specificity protein kinase KNS1

 Dual specificity protein kinase KNS1 ELISA Kit
 Dual specificity protein kinase KNS1 Recombinant
 Dual specificity protein kinase KNS1 Antibody
Nonessential protein kinase.
 KNS1 ELISA Kit
 KNS1 Recombinant
 KNS1 Antibody
 YLL019C ELISA Kit
 YLL019C Recombinant
 YLL019C Antibody
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Dual specificity protein kinase lkh1

 Dual specificity protein kinase lkh1 ELISA Kit
 Dual specificity protein kinase lkh1 Recombinant
 Dual specificity protein kinase lkh1 Antibody
Protein kinase that may act as a negative regulator of filamentous growth and flocculation. Appears to have a role in normal cell wall and septum formation and in cell separation. May have antagonistic function in the regulation of beta-glucan distribution between the sites for cell wall and septum assembly.
 lkh1 ELISA Kit
 lkh1 Recombinant
 lkh1 Antibody
 kic1 ELISA Kit
 kic1 Recombinant
 kic1 Antibody
 SPAC1D4.11c ELISA Kit
 SPAC1D4.11c Recombinant
 SPAC1D4.11c Antibody
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Dual specificity protein kinase pom1

 Dual specificity protein kinase pom1 ELISA Kit
 Dual specificity protein kinase pom1 Recombinant
 Dual specificity protein kinase pom1 Antibody
Involved in localization of polarized growth and cytokinesis. May interact with both the actin and microtubule cytoskeleton. Requires tea1 for localization to the cell ends but not to the cell center.
 pom1 ELISA Kit
 pom1 Recombinant
 pom1 Antibody
 SPAC2F7.03c ELISA Kit
 SPAC2F7.03c Recombinant
 SPAC2F7.03c Antibody
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Dual specificity protein kinase pyk3

 Dual specificity protein kinase pyk3 ELISA Kit
 Dual specificity protein kinase pyk3 Recombinant
 Dual specificity protein kinase pyk3 Antibody
Also known as Dual specificity protein kinase pyk3 (Tyrosine-protein kinase 3).
Involved in the development. Negatively regulates tyrosine phosphorylation and activation state of dstC/STATc, probably by activating a dstC/STATc phosphatase.
 pyk3 ELISA Kit
 pyk3 Recombinant
 pyk3 Antibody
 DpyK3 ELISA Kit
 DpyK3 Recombinant
 DpyK3 Antibody
 pkyA ELISA Kit
 pkyA Recombinant
 pkyA Antibody
 DDB_G0289001 ELISA Kit
 DDB_G0289001 Recombinant
 DDB_G0289001 Antibody
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Dual specificity protein kinase shkA

 Dual specificity protein kinase shkA ELISA Kit
 Dual specificity protein kinase shkA Recombinant
 Dual specificity protein kinase shkA Antibody
Also known as Dual specificity protein kinase shkA (SH2 domain-containing protein 1) (SH2 domain-containing protein A).
Required for proper chemotaxis and phagocytosis; proper spatiotemporal control of F-actin levels in chemotaxing cells. Negative regulator of the PI3K (phosphatidylinositol 3 kinase) pathway. Predominantly phosphorylates serines and threonines and tyrosines at a lower level.
 shkA ELISA Kit
 shkA Recombinant
 shkA Antibody
 shk1 ELISA Kit
 shk1 Recombinant
 shk1 Antibody
 DDB_G0283267 ELISA Kit
 DDB_G0283267 Recombinant
 DDB_G0283267 Antibody
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Dual specificity protein kinase shkB

 Dual specificity protein kinase shkB ELISA Kit
 Dual specificity protein kinase shkB Recombinant
 Dual specificity protein kinase shkB Antibody
Also known as Dual specificity protein kinase shkB (SH2 domain-containing protein 2) (SH2 domain-containing protein B).
Required for proper chemotaxis and phagocytosis; proper spatiotemporal control of F-actin levels in chemotaxing cells. Negative regulator of the PI3K (phosphatidylinositol 3 kinase) pathway. Predominantly phosphorylates serines and threonines and tyrosines at a lower level ().
 shkB ELISA Kit
 shkB Recombinant
 shkB Antibody
 DDB_G0288617 ELISA Kit
 DDB_G0288617 Recombinant
 DDB_G0288617 Antibody
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Dual specificity protein kinase shkC

 Dual specificity protein kinase shkC ELISA Kit
 Dual specificity protein kinase shkC Recombinant
 Dual specificity protein kinase shkC Antibody
Also known as Dual specificity protein kinase shkC (SH2 domain-containing protein 3) (SH2 domain-containing protein C).
Required for proper chemotaxis and phagocytosis; proper spatiotemporal control of F-actin levels in chemotaxing cells. Negative regulator of the PI3K (phosphatidylinositol 3 kinase) pathway. Predominantly phosphorylates serines and threonines and tyrosines at a lower level ().
 shkC ELISA Kit
 shkC Recombinant
 shkC Antibody
 DDB_G0278409 ELISA Kit
 DDB_G0278409 Recombinant
 DDB_G0278409 Antibody
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Dual specificity protein kinase shkD

 Dual specificity protein kinase shkD ELISA Kit
 Dual specificity protein kinase shkD Recombinant
 Dual specificity protein kinase shkD Antibody
Also known as Dual specificity protein kinase shkD (SH2 domain-containing protein 4) (SH2 domain-containing protein D).
Required for proper chemotaxis and phagocytosis; proper spatiotemporal control of F-actin levels in chemotaxing cells. Negative regulator of the PI3K (phosphatidylinositol 3 kinase) pathway. Predominantly phosphorylates serines and threonines and tyrosines at a lower level ().
 shkD ELISA Kit
 shkD Recombinant
 shkD Antibody
 DDB_G0281343 ELISA Kit
 DDB_G0281343 Recombinant
 DDB_G0281343 Antibody
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Dual specificity protein kinase shkE

 Dual specificity protein kinase shkE ELISA Kit
 Dual specificity protein kinase shkE Recombinant
 Dual specificity protein kinase shkE Antibody
Also known as Dual specificity protein kinase shkE (SH2 domain-containing protein 5) (SH2 domain-containing protein E).
Required for proper chemotaxis and phagocytosis; proper spatiotemporal control of F-actin levels in chemotaxing cells. Negative regulator of the PI3K (phosphatidylinositol 3 kinase) pathway. Predominantly phosphorylates serines and threonines and tyrosines at a lower level ().
 shkE ELISA Kit
 shkE Recombinant
 shkE Antibody
 DDB_G0290451 ELISA Kit
 DDB_G0290451 Recombinant
 DDB_G0290451 Antibody
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Dual specificity protein kinase splA

 Dual specificity protein kinase splA ELISA Kit
 Dual specificity protein kinase splA Recombinant
 Dual specificity protein kinase splA Antibody
Also known as Dual specificity protein kinase splA (Non-receptor tyrosine kinase spore lysis A) (Tyrosine-protein kinase 1).
Essential for spore differentiation.
 splA ELISA Kit
 splA Recombinant
 splA Antibody
 DpyK1 ELISA Kit
 DpyK1 Recombinant
 DpyK1 Antibody
 pyK1 ELISA Kit
 pyK1 Recombinant
 pyK1 Antibody
 pykA ELISA Kit
 pykA Recombinant
 pykA Antibody
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Dual specificity protein kinase splB

 Dual specificity protein kinase splB ELISA Kit
 Dual specificity protein kinase splB Recombinant
 Dual specificity protein kinase splB Antibody
Also known as Dual specificity protein kinase splB (Non-receptor tyrosine kinase spore lysis B) (Tyrosine-protein kinase 2).
 splB ELISA Kit
 splB Recombinant
 splB Antibody
 DpyK2 ELISA Kit
 DpyK2 Recombinant
 DpyK2 Antibody
 pyk2 ELISA Kit
 pyk2 Recombinant
 pyk2 Antibody
 pykB ELISA Kit
 pykB Recombinant
 pykB Antibody
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Dual specificity protein kinase TTK

 Dual specificity protein kinase TTK ELISA Kit
 Dual specificity protein kinase TTK Recombinant
 Dual specificity protein kinase TTK Antibody
Phosphorylates proteins on serine, threonine, and tyrosine. Probably associated with cell proliferation. Essential for chromosome alignment by enhancing AURKB activity (via direct CDCA8 phosphorylation) at the centromere, and for the mitotic checkpoint ().
 TTK ELISA Kit
 TTK Recombinant
 TTK Antibody
 QtsA-10742 ELISA Kit
 QtsA-10742 Recombinant
 QtsA-10742 Antibody
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Dual specificity protein kinase YAK1

 Dual specificity protein kinase YAK1 ELISA Kit
 Dual specificity protein kinase YAK1 Recombinant
 Dual specificity protein kinase YAK1 Antibody
Negative regulator of the cell cycle acting downstream of the cAMP-dependent protein kinase. Part of a glucose-sensing system involved in growth control in response to glucose availability. Phosphorylates POP2.
 YAK1 ELISA Kit
 YAK1 Recombinant
 YAK1 Antibody
 YJL141C ELISA Kit
 YJL141C Recombinant
 YJL141C Antibody
 J0652 ELISA Kit
 J0652 Recombinant
 J0652 Antibody
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Dual specificity protein kinase zak2

 Dual specificity protein kinase zak2 ELISA Kit
 Dual specificity protein kinase zak2 Recombinant
 Dual specificity protein kinase zak2 Antibody
Also known as Dual specificity protein kinase zak2 (Tyrosine-protein kinase 4) (Zaphod K Kinase 2) (Zaphod kinase 2).
Positive regulator of gsk3/gskA activity required for cell pattern formation and a downstream effector of carC. The kinases, gsk3/gskA, zakA and zak2, form part of a signaling pathway that responds to extracellular cyclic AMP. The pathway has a role in transcriptional regulation; required to direct prespore/spore fates during development. Zak2 negatively regulates prestalk differentiation by regulating expression of ecmA. Phosphorylates Y-214 of gsk3/gskA, in vitro.
 zak2 ELISA Kit
 zak2 Recombinant
 zak2 Antibody
 DpyK4 ELISA Kit
 DpyK4 Recombinant
 DpyK4 Antibody
 pyk4 ELISA Kit
 pyk4 Recombinant
 pyk4 Antibody
 DDB_G0276187 ELISA Kit
 DDB_G0276187 Recombinant
 DDB_G0276187 Antibody
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Dual specificity protein kinase zakA

 Dual specificity protein kinase zakA ELISA Kit
 Dual specificity protein kinase zakA Recombinant
 Dual specificity protein kinase zakA Antibody
Also known as Dual specificity protein kinase zakA (Zaphod K Kinase 1) (Zaphod kinase 1) (Zaphod kinase A).
Positive regulator of gsk3/gskA activity required for cell pattern formation and a downstream effector of carC. The kinases, gsk3/gskA, zakA and zak2, form part of a signaling pathway that responds to extracellular cyclic AMP. The pathway has a role in transcriptional regulation; required to direct prespore/spore fates during development. ZakA negatively regulates prestalk differentiation by regulating expression of ecmB. Phosphorylates Y-214 of gsk3/gskA, in vitro.
 zakA ELISA Kit
 zakA Recombinant
 zakA Antibody
 zak1 ELISA Kit
 zak1 Recombinant
 zak1 Antibody
 DDB_G0276025 ELISA Kit
 DDB_G0276025 Recombinant
 DDB_G0276025 Antibody
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