Antibody Protein ELISA Kit from MyBioSource header Telephone 1.858.633.0165          
1.855.MyBioSource
Fax 1.858.633.0166    Email sales@mybiosource.com 
tel/fax
menu1 Home Products Ordering Company Help menu7
bottom
   MyBioSource  rightarrow Protein Family  rightarrow Dysferlin  rightarrow LOG IN  rightarrow MY ACCOUNT  rightarrow CART CONTENTS  rightarrow CHECKOUT 
horiz bar
MyBioSource Menu separator
separator
ELISA Kit ELISA Kit
CLIA Kit CLIA Kit
PCR Kit PCR Kit
Monoclonal Antibody Monoclonal Antibody
Polyclonal Antibody Polyclonal Antibody
Secondary Antibody Secondary Antibody
Antigen Antigen
Biochemical Biochemical
cDNA Clone cDNA Clone
siRNA siRNA
Peptide Peptide
Recombinant/Purified Protein Rec./Purified Protein

Custom ELISA Kit Custom ELISA Kit
Custom Protein Custom Protein
Custom Antibody Custom Antibody
Antibody Matched Pairs Antibody Matched Pairs
Antibody & Corresponding Blocking Peptide Pairs Antibody Peptide Pairs
Phospho-Specific Antibodies Phospho Antibodies
Products by Disease Products by Disease
Products by Pathway Products by Pathway
Products by Tissue Products by Tissue

arrow Advanced Search
arrow Submit Technical Q&A
arrow International Distributors
arrow Contact Us
separator
Our Best Sellers moreseparator
separator
 • Thyroxine Antibody
 • Beta-crystallin A2 (CRYBA2) Recombinant Protein
 • TCR gamma delta Antibody
 • A Disintegrin and Metalloprotease 7 (ADAM7) ELISA Kit
 • KGF Recombinant Protein
 • Apolipoprotein AII (APOA2) Antibody
 • Tubulin-gamma (TUBG1) Antibody
 • hydrogenperoxide (H2O2) ELISA Kit
 • RORC - ROR Gamma Antibody
 • prostaglandin-endoperoxide synthase 1 (prostaglandin G-H syn... ELISA Kit
 • allograft inflammatory factor 1 (AIF1) ELISA Kit
 • IgG Fc (FCGR3B) Secondary Antibody
 • Ob-R Antibody
 • Nuclease-sensitive element-binding protein 1 (Ybx1) Recombinant Protein
 downarrow more ...
separator

Dysferlin

separator
Key calcium ion sensor involved in the Ca(2+)-triggered synaptic vesicle-plasma membrane fusion. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress.

Below are the list of possible Dysferlin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Dysferlin

 Dysferlin ELISA Kit
 Dysferlin Recombinant
 Dysferlin Antibody
Also known as Dysferlin (Dystrophy-associated fer-1-like protein) (Fer-1-like protein 1).
DYSF: Key calcium ion sensor involved in the Ca(2+)-triggered synaptic vesicle-plasma membrane fusion. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress. Defects in DYSF are the cause of limb-g
>>>
irdle muscular dystrophy type 2B (LGMD2B). LGMD2B is an autosomal recessive degenerative myopathy characterized by weakness and atrophy starting in the proximal pelvifemoral muscles, with onset in the late teens or later, massive elevation of serum creatine kinase levels and slow progression. Scapular muscle involvement is minor and not present at onset. Upper limb girdle involvement follows some years after the onset in lower limbs. Defects in DYSF are the cause of Miyoshi muscular dystrophy type 1 (MMD1). MMD1 is a late-onset muscular dystrophy involving the distal lower limb musculature. It is characterized by weakness that initially affects the gastrocnemius muscle during early adulthood. Otherwise the phenotype overlaps with LGMD2B, especially in age at onset and creatine kinase elevation. Defects in DYSF are the cause of distal myopathy with anterior tibial onset (DMAT). Onset of the disorder is between 14 and 28 years of age and the anterior tibial muscles are the first muscle group to be involved. Inheritance is autosomal recessive. Belongs to the ferlin family. 15 isoforms of the human protein are produced by alternative splicing.

Protein type: Calcium-binding; Membrane protein, integral; Vesicle

Cellular Component: cytoplasm; cytoplasmic vesicle; early endosome; endocytic vesicle; endosome; lamellipodium; late endosome; plasma membrane; sarcolemma; T-tubule

Molecular Function: calcium ion binding; calcium-dependent phospholipid binding; phospholipid binding; protein binding

Biological Process: plasma membrane repair; vesicle fusion
 Dysf ELISA Kit
 Dysf Recombinant
 Dysf Antibody
 Fer1l1 ELISA Kit
 Fer1l1 Recombinant
 Fer1l1 Antibody
Table BarTOPTable Bar
Proteins Root Name Listing
horiz bar
 SSL   Follow us on Facebook Follow us onTwitter Follow us on Google Plus Connect us on LinkedIn Subscribe to our RSS Feed for latest products and special promotions