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E1A-binding protein

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Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. May be required for transcriptional activation of E2F1 and MYC target genes during cellular proliferation. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. May regulate ZNF42 transcription activity. Component of a SWR1-like complex that specifically mediates the removal of histone H2A.Z/H2AFZ from the nucleosome.

Below are the list of possible E1A-binding protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

E1A-binding protein p400

 E1A-binding protein p400 ELISA Kit
 E1A-binding protein p400 Recombinant
 E1A-binding protein p400 Antibody
Also known as E1A-binding protein p400 (CAG repeat protein 32) (Domino homolog) (hDomino) (Trinucleotide repeat-containing gene 12 protein) (p400 kDa SWI2/SNF2-related protein).
p400: Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. May be required for transcriptional activation of E2F1 an
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d MYC target genes during cellular proliferation. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. May regulate ZNF42 transcription activity. Belongs to the SNF2/RAD54 helicase family. SWR1 subfamily. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Apoptosis; EC 3.6.1.-; EC 3.6.4.-; Helicase

Chromosomal Location of Human Ortholog: 12q24.33

Cellular Component: NuA4 histone acetyltransferase complex; nuclear speck; nucleoplasm

Molecular Function: protein binding
 EP400 ELISA Kit
 EP400 Recombinant
 EP400 Antibody
 CAGH32 ELISA Kit
 CAGH32 Recombinant
 CAGH32 Antibody
 KIAA1498 ELISA Kit
 KIAA1498 Recombinant
 KIAA1498 Antibody
 KIAA1818 ELISA Kit
 KIAA1818 Recombinant
 KIAA1818 Antibody
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