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Early 4 ORF6 protein

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Plays a major role to prevent cellular inhibition of viral genome replication by nuclear bodies. Assembles an SCF-like E3 ubiquitin ligase complex based on the cellular proteins ELOB, ELOC, CUL5 and RBX1, in cooperation with viral E1B-55K. This viral RING-type ligase ubiquitinates cellular substrates prior to proteasomal degradation: p53/TP53, LIG4, MRE11-RAD50-NBS1 (MRN) complex, ITGA3, DAXX and BLM.

Below are the list of possible Early 4 ORF6 protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Early 4 ORF6 protein

 Early 4 ORF6 protein ELISA Kit
 Early 4 ORF6 protein Recombinant
 Early 4 ORF6 protein Antibody
Also known as Early 4 ORF6 protein (E4-ORF6) (Early 4 34 kDa protein) (E4-34k).
Plays a major role to prevent cellular inhibition of viral genome replication by nuclear bodies. Assembles an SCF-lik
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e E3 ubiquitin ligase complex based on the cellular proteins TCEB2, TCEB1, CUL5 and RBX1, in cooperation with viral E1B-55K. This viral RING-type ligase ubiquitinates cellular substrates prior to proteasomal degradation: p53/TP53, LIG4, MRE11-RAD50-NBS1 (MRN) complex, ITGA3, DAXX and BLM.
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