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Ectonucleoside triphosphate diphosphohydrolase

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In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well.

Below are the list of possible Ectonucleoside triphosphate diphosphohydrolase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Ectonucleoside triphosphate diphosphohydrolase 1

 Ectonucleoside triphosphate diphosphohydrolase 1 ELISA Kit
 Ectonucleoside triphosphate diphosphohydrolase 1 Recombinant
 Ectonucleoside triphosphate diphosphohydrolase 1 Antibody
Also known as Ectonucleoside triphosphate diphosphohydrolase 1 (NTPDase 1) (Ecto-ATP diphosphohydrolase 1) (Ecto-ATPDase 1) (Ecto-ATPase 1) (Ecto-apyrase) (Lymphoid cell activation antigen) (CD antigen CD39).
ENTPD1: an ectonucleotidase that, like CD73, hydrolyzes immunostimulatory ATP, and ADP, to immunosuppressive AMP. May inhibit host immune responses against cancer. Expressed at high level
>>>
s in malignant epithelial cells of human rectal adenocarcinoma. A prognostic marker of chronic lymphocytic leukemia that may identify patients with an unfavorable clinical outcome. Synergizes with CD161 to modulate Th17 responses in Crohn's disease. It may hydrolyze ATP and other nucleotides in the nervous system to regulate purinergic neurotransmission in the nervous system. May be implicated in inhibiting platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well. Belongs to the GDA1/CD39 NTPase family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.6.1.5; Extracellular matrix; Hydrolase; Membrane protein, integral; Membrane protein, multi-pass; Nucleotide Metabolism - purine; Nucleotide Metabolism - pyrimidine

Cellular Component: basal lamina; basolateral plasma membrane; cell soma; cell surface; extracellular space; membrane; neuron projection; postsynaptic density; synaptic vesicle

Molecular Function: adenosine-diphosphatase activity; ATPase activity; identical protein binding; nucleoside-diphosphatase activity; nucleoside-triphosphatase activity

Biological Process: G-protein coupled receptor protein signaling pathway; negative regulation of dopamine secretion; platelet activation; protein homooligomerization; purine ribonucleoside diphosphate catabolic process; response to ATP; response to caffeine; response to gamma radiation; response to lipopolysaccharide; response to morphine; response to proline
 Entpd1 ELISA Kit
 Entpd1 Recombinant
 Entpd1 Antibody
 Cd39 ELISA Kit
 Cd39 Recombinant
 Cd39 Antibody
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Ectonucleoside triphosphate diphosphohydrolase 2

 Ectonucleoside triphosphate diphosphohydrolase 2 ELISA Kit
 Ectonucleoside triphosphate diphosphohydrolase 2 Recombinant
 Ectonucleoside triphosphate diphosphohydrolase 2 Antibody
Also known as Ectonucleoside triphosphate diphosphohydrolase 2 (NTPDase 2) (CD39 antigen-like 1) (Ecto-ATP diphosphohydrolase 2) (Ecto-ATPDase 2) (Ecto-ATPase 2).
ENTPD2: In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Hydrolyzes ADP only to a marginal extent. The order of activity with different substrates is ATP > GTP > CTP = IT
>>>
P > UTP >> ADP = UDP. Belongs to the GDA1/CD39 NTPase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 3.6.1.-; Extracellular matrix; Hydrolase; Membrane protein, integral; Membrane protein, multi-pass; Nucleotide Metabolism - purine

Cellular Component: basal lamina; cell projection membrane; cell surface; plasma membrane

Molecular Function: adenosine-diphosphatase activity; ATPase activity; identical protein binding; nucleoside-diphosphatase activity; nucleoside-triphosphatase activity; protein binding

Biological Process: G-protein coupled receptor protein signaling pathway; platelet activation; protein homooligomerization; purine ribonucleoside diphosphate catabolic process
 Entpd2 ELISA Kit
 Entpd2 Recombinant
 Entpd2 Antibody
 Cd39l1 ELISA Kit
 Cd39l1 Recombinant
 Cd39l1 Antibody
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Ectonucleoside triphosphate diphosphohydrolase 3

 Ectonucleoside triphosphate diphosphohydrolase 3 ELISA Kit
 Ectonucleoside triphosphate diphosphohydrolase 3 Recombinant
 Ectonucleoside triphosphate diphosphohydrolase 3 Antibody
Also known as Ectonucleoside triphosphate diphosphohydrolase 3 (NTPDase 3) (CD39 antigen-like 3) (Ecto-ATP diphosphohydrolase 3) (Ecto-ATPDase 3) (Ecto-ATPase 3) (Ecto-apyrase 3) (HB6).
ENTPD3: Has a threefold preference for the hydrolysis of ATP over ADP. Belongs to the GDA1/CD39 NTPase family.

Protein type: EC 3.6.1.5; Hydrolase; Membrane protein, integral; Membrane protein, multi-pass
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; Nucleotide Metabolism - purine; Nucleotide Metabolism - pyrimidine; Phosphatase (non-protein)

Chromosomal Location of Human Ortholog: 3p21.3

Molecular Function: protein binding
 ENTPD3 ELISA Kit
 ENTPD3 Recombinant
 ENTPD3 Antibody
 CD39L3 ELISA Kit
 CD39L3 Recombinant
 CD39L3 Antibody
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Ectonucleoside triphosphate diphosphohydrolase 4

 Ectonucleoside triphosphate diphosphohydrolase 4 ELISA Kit
 Ectonucleoside triphosphate diphosphohydrolase 4 Recombinant
 Ectonucleoside triphosphate diphosphohydrolase 4 Antibody
Also known as Ectonucleoside triphosphate diphosphohydrolase 4 (NTPDase 4) (Lysosomal apyrase-like protein of 70 kDa) (Uridine-diphosphatase) (UDPase).
UDPase: an ectonucleoside triphosphate diphosphohydrolase. Hydrolyzes preferentially nucleoside 5'-diphosphates; nucleoside 5'-triphosphates are hydrolyzed only to a minor extent. The order of activity with different substrates is UDP >> GDP = CDP = TDP; AMP, ADP, ATP and UMP are not substrates. Two splice variant isoforms have been described. Preferred substrates for isoform 2 are CTP, UDP, CDP, GTP and GDP, while isoform 1 utilizes U
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TP and TTP

Protein type: EC 3.6.1.6; Hydrolase; Membrane protein, integral; Membrane protein, multi-pass; Nucleotide Metabolism - purine; Nucleotide Metabolism - pyrimidine

Cellular Component: integral to Golgi membrane; intracellular membrane-bound organelle

Molecular Function: uridine-diphosphatase activity

Biological Process: UDP catabolic process
 Entpd4 ELISA Kit
 Entpd4 Recombinant
 Entpd4 Antibody
 Lalp70 ELISA Kit
 Lalp70 Recombinant
 Lalp70 Antibody
 Lysal1 ELISA Kit
 Lysal1 Recombinant
 Lysal1 Antibody
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Ectonucleoside triphosphate diphosphohydrolase 5

 Ectonucleoside triphosphate diphosphohydrolase 5 ELISA Kit
 Ectonucleoside triphosphate diphosphohydrolase 5 Recombinant
 Ectonucleoside triphosphate diphosphohydrolase 5 Antibody
Also known as Ectonucleoside triphosphate diphosphohydrolase 5 (NTPDase 5) (CD39 antigen-like 4) (ER-UDPase) (Guanosine-diphosphatase ENTPD5) (GDPase ENTPD5) (Nucleoside diphosphatase) (Uridine-diphosphatase ENTPD5) (UDPase ENTPD5).
ENTPD5: Uridine diphosphatase (UDPase) that promotes protein N- glycosylation and ATP level regulation. UDP hydrolysis promotes protein N-glycosylation and folding
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in the endoplasmic reticulum, as well as elevated ATP consumption in the cytosol via an ATP hydrolysis cycle. Together with CMPK1 and AK1, constitutes an ATP hydrolysis cycle that converts ATP to AMP and results in a compensatory increase in aerobic glycolysis. Also hydrolyzes GDP and IDP but not any other nucleoside di-, mono- or triphosphates, nor thiamine pyrophosphate. Plays a key role in the AKT1-PTEN signaling pathway by promoting glycolysis in proliferating cells in response to phosphoinositide 3-kinase (PI3K) signaling. Belongs to the GDA1/CD39 NTPase family.

Protein type: EC 3.6.1.42; EC 3.6.1.6; Hydrolase; Nucleotide Metabolism - purine; Nucleotide Metabolism - pyrimidine; Oncoprotein

Cellular Component: endoplasmic reticulum

Molecular Function: guanosine-diphosphatase activity; uridine-diphosphatase activity

Biological Process: 'de novo' posttranslational protein folding; ATP metabolic process; cell growth; cell proliferation; positive regulation of glycolysis; protein amino acid N-linked glycosylation; regulation of phosphoinositide 3-kinase cascade
 Entpd5 ELISA Kit
 Entpd5 Recombinant
 Entpd5 Antibody
 Cd39l4 ELISA Kit
 Cd39l4 Recombinant
 Cd39l4 Antibody
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Ectonucleoside triphosphate diphosphohydrolase 6

 Ectonucleoside triphosphate diphosphohydrolase 6 ELISA Kit
 Ectonucleoside triphosphate diphosphohydrolase 6 Recombinant
 Ectonucleoside triphosphate diphosphohydrolase 6 Antibody
Also known as Ectonucleoside triphosphate diphosphohydrolase 6 (NTPDase 6) (CD39 antigen-like 2).
ENTPD6: Might support glycosylation reactions in the Golgi apparatus and, when released from cells, might catalyze the hydrolysis of extracellular nucleotides. Hydrolyzes preferentially nucleoside 5'-diphosphates, nucleoside 5'-triphosphates are hydrolyzed only to a minor extent, there is no hydrolysis of nucleoside 5'-monophosphates. The order of activity with different substrates is GDP > IDP >> UDP = CDP >> ADP. Belongs to the GDA1/CD39 NTPase family. 2 isoforms of the human p
>>>
rotein are produced by alternative splicing.

Protein type: EC 3.6.1.6; Hydrolase; Membrane protein, integral; Nucleotide Metabolism - purine; Nucleotide Metabolism - pyrimidine

Chromosomal Location of Human Ortholog: 20p11.21
 ENTPD6 ELISA Kit
 ENTPD6 Recombinant
 ENTPD6 Antibody
 CD39L2 ELISA Kit
 CD39L2 Recombinant
 CD39L2 Antibody
 IL6ST2 ELISA Kit
 IL6ST2 Recombinant
 IL6ST2 Antibody
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Ectonucleoside triphosphate diphosphohydrolase 7

 Ectonucleoside triphosphate diphosphohydrolase 7 ELISA Kit
 Ectonucleoside triphosphate diphosphohydrolase 7 Recombinant
 Ectonucleoside triphosphate diphosphohydrolase 7 Antibody
Also known as Ectonucleoside triphosphate diphosphohydrolase 7 (NTPDase 7).
Preferentially hydrolyzes nucleoside 5'-triphosphates. The order of activity with respect to possible substrates is UTP > GTP > CTP ().
 entpd7 ELISA Kit
 entpd7 Recombinant
 entpd7 Antibody
 TGas060f02.1 ELISA Kit
 TGas060f02.1 Recombinant
 TGas060f02.1 Antibody
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Ectonucleoside triphosphate diphosphohydrolase 8

 Ectonucleoside triphosphate diphosphohydrolase 8 ELISA Kit
 Ectonucleoside triphosphate diphosphohydrolase 8 Recombinant
 Ectonucleoside triphosphate diphosphohydrolase 8 Antibody
Also known as Ectonucleoside triphosphate diphosphohydrolase 8 (E-NTPDase 8) (NTPDase 8) (NTPDase8).
Canalicular ectonucleoside NTPDase responsible for the main hepatic NTPDase activity. Ectonucleoside NTPDases catalyze the hydrolysis of gamma- and beta-phosphate residues of nucleotides, playing a central role in concentration of extracellular nucleotides. Has activity toward ATP, ADP, UTP and
>>>
UDP, but not toward AMP ().
 Entpd8 ELISA Kit
 Entpd8 Recombinant
 Entpd8 Antibody
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