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EH domain-containing protein

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ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis. Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Recruited to endosomal membranes upon nerve growth factor stimulation, indirectly regulates neurite outgrowth. Plays a role in myoblast fusion. Involved in the unidirectional retrograde dendritic transport of endocytosed BACE1 and in efficient sorting of BACE1 to axons implicating a function in neuronal APP processing. Plays a role in the formation of the ciliary vesicle (CV), an early step in cilium biogenesis. Proposed to be required for the fusion of distal appendage vesicles (DAVs) to form the CV by recruiting SNARE complex component SNAP29. Is required for recruitment of transition zone proteins CEP290, RPGRIP1L, TMEM67 and B9D2, and of IFT20 following DAV reorganization before Rab8-dependent ciliary membrane extension. Required for the loss of CCP110 form the mother centriole essential for the maturation of the basal body during ciliogenesis.

Below are the list of possible EH domain-containing protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

EH domain-containing protein 1

 EH domain-containing protein 1 ELISA Kit
 EH domain-containing protein 1 Recombinant
 EH domain-containing protein 1 Antibody
ATP- and membrane-binding protein that controls membrane reorganization/tubulation upon ATP hydrolysis. Acts in early endocytic membrane fusion and membrane trafficking of recycling endosomes. Recruited to endosomal membranes upon nerve growth factor stimulation, indirectly regulates neurite outgrowth. Plays a role in myoblast fusion. Involved in the unidirectional retrograde dendritic transport o
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f endocytosed BACE1 and in efficient sorting of BACE1 to axons implicating a function in neuronal APP processing. Plays a role in the formation of the ciliary vesicle (CV), an early step in cilium biogenesis. Proposed to be required for the fusion of distal appendage vesicles (DAVs) to form the CV by recruiting SNARE complex component SNAP29. Is required for recruitment of transition zone proteins CEP290, RPGRIP1L, TMEM67 and B9D2, and of IFT20 following DAV reorganization before Rab8-dependent ciliary membrane extension. Required for the loss of CCP110 form the mother centriole essential for the maturation of the basal body during ciliogenesis.
 EHD1 ELISA Kit
 EHD1 Recombinant
 EHD1 Antibody
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EH domain-containing protein 2

 EH domain-containing protein 2 ELISA Kit
 EH domain-containing protein 2 Recombinant
 EH domain-containing protein 2 Antibody
EHD2: Plays a role in membrane reorganization in response to nucleotide hydrolysis. Binds to liposomes and deforms them into tubules. Plays a role in membrane trafficking between the plasma membrane and endosomes. Important for the internalization of GLUT4. Required for normal fusion of myoblasts to skeletal muscle myotubes. Binds ATP; does not bind GTP.

Protein type: Vesicle

Cellula
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r Component: caveola; cytosol; extrinsic to membrane; membrane; perinuclear region of cytoplasm; plasma membrane; recycling endosome membrane

Molecular Function: protein binding; protein domain specific binding

Biological Process: cortical actin cytoskeleton organization and biogenesis; endocytic recycling; endocytosis
 Ehd2 ELISA Kit
 Ehd2 Recombinant
 Ehd2 Antibody
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EH domain-containing protein 3

 EH domain-containing protein 3 ELISA Kit
 EH domain-containing protein 3 Recombinant
 EH domain-containing protein 3 Antibody
EHD3: Plays a role in endocytic transport.

Cellular Component: cytoplasm; endocytic vesicle; focal adhesion; myelin sheath; perinuclear region of cytoplasm; recycling endosome membrane

Molecular Function: protein binding

Biological Process: endocytic recycling; protein homooligomerization; receptor recycling
 Ehd3 ELISA Kit
 Ehd3 Recombinant
 Ehd3 Antibody
 Ehd2 ELISA Kit
 Ehd2 Recombinant
 Ehd2 Antibody
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EH domain-containing protein 4

 EH domain-containing protein 4 ELISA Kit
 EH domain-containing protein 4 Recombinant
 EH domain-containing protein 4 Antibody
Also known as EH domain-containing protein 4 (Hepatocellular carcinoma-associated protein 10/11) (PAST homolog 4).
EHD4: an extracellular matrix protein that associates with type VI collagen. Contains 1 EF-hand calcium-binding domain and an EH domain. Highly expressed in heart and pancreas.

Protein type: Extracellular matrix

Chromosomal Location of Human Ortholog: 15q11.1

Cellular Component: cell-cell adherens junction; endoplasmic reticulum; membrane; nucleus; recycling endosome membrane

Molecular Function: nucleic acid binding; protein binding

Biological
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Process: endocytic recycling; protein homooligomerization
 EHD4 ELISA Kit
 EHD4 Recombinant
 EHD4 Antibody
 HCA10 ELISA Kit
 HCA10 Recombinant
 HCA10 Antibody
 HCA11 ELISA Kit
 HCA11 Recombinant
 HCA11 Antibody
 PAST4 ELISA Kit
 PAST4 Recombinant
 PAST4 Antibody
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