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Electrogenic sodium bicarbonate cotransporter

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Electrogenic sodium/bicarbonate cotransporter with a Na(+):HCO3(-) stoichiometry varying from 1:2 to 1:3. May regulate bicarbonate influx/efflux at the basolateral membrane of cells and regulate intracellular pH.

Below are the list of possible Electrogenic sodium bicarbonate cotransporter products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Electrogenic sodium bicarbonate cotransporter 1

 Electrogenic sodium bicarbonate cotransporter 1 ELISA Kit
 Electrogenic sodium bicarbonate cotransporter 1 Recombinant
 Electrogenic sodium bicarbonate cotransporter 1 Antibody
Also known as Electrogenic sodium bicarbonate cotransporter 1 (Sodium bicarbonate cotransporter) (Na(+)/HCO3(-) cotransporter) (Solute carrier family 4 member 4).
SLC4A4: Electrogenic sodium/bicarbonate cotransporter with a Na(+):HCO3(-) stoichiometry varying from 1:2 to 1:3. May regulate bicarbonate influx/efflux at the basolateral membrane of cells and regulate intracellular pH. Defects in SLC4A4 are the cause of proximal renal tubular acidosis with ocular abnormalities (pRTA-OA); also known as renal tubular acidosis II. Caused by an impairment of bicarbonate absorption in the proximal tu
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bule, proximal renal tubular acidosis (pRTA) is characterized by a decreased renal HCO3(-) threshold. pRTA-OA is an extremely rare autosomal recessive syndrome characterized by short stature, profound pRTA, mental retardation, bilateral glaucoma, cataracts and bandkeratopathy. Loss of interaction with and stimulation by CA4 is the cause of retinitis pigmentosa type 17 (RP17). Belongs to the anion exchanger (TC 2.A.31) family. 5 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family

Cellular Component: basolateral plasma membrane; integral to plasma membrane

Molecular Function: anion transmembrane transporter activity; protein binding; sodium:bicarbonate symporter activity

Biological Process: bicarbonate transport; regulation of intracellular pH; regulation of pH; sodium ion transport
 Slc4a4 ELISA Kit
 Slc4a4 Recombinant
 Slc4a4 Antibody
 Nbc1 ELISA Kit
 Nbc1 Recombinant
 Nbc1 Antibody
 Nbce1 ELISA Kit
 Nbce1 Recombinant
 Nbce1 Antibody
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Electrogenic sodium bicarbonate cotransporter 4

 Electrogenic sodium bicarbonate cotransporter 4 ELISA Kit
 Electrogenic sodium bicarbonate cotransporter 4 Recombinant
 Electrogenic sodium bicarbonate cotransporter 4 Antibody
Also known as Electrogenic sodium bicarbonate cotransporter 4 (NBCe2) (Solute carrier family 4 member 5).
SLC4A5: Mediates sodium- and bicarbonate-dependent electrogenic sodium bicarbonate cotransport, with a Na(+):HCO3(-) stoichiometry of 2:1. May have a housekeeping function in regulating the pH of tissues in which it is expressed. May play a role in mediating Na(+):HCO3(-) cotransport in hep
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atocytes and intrahepatic cholangiocytes. Also may be important in protecting the renal paranchyma from alterations in urine pH. Belongs to the anion exchanger (TC 2.A.31) family. 8 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family

Chromosomal Location of Human Ortholog: 2p13

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: anion transmembrane transporter activity; sodium:bicarbonate symporter activity

Biological Process: bicarbonate transport; regulation of intracellular pH; renal system process
 SLC4A5 ELISA Kit
 SLC4A5 Recombinant
 SLC4A5 Antibody
 NBC4 ELISA Kit
 NBC4 Recombinant
 NBC4 Antibody
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