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Electroneutral sodium bicarbonate exchanger

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Mediates electroneutral sodium- and carbonate-dependent chloride-HCO3(-) exchange with a Na(+):HCO3(-) stoichiometry of 2:1. Plays a major role in pH regulation in neurons. May be involved in cell pH regulation by transporting HCO3(-) from blood to cell. Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3(-) into the cells. Also mediates lithium-dependent HCO3(-) cotransport. May be regulated by osmolarity.

Below are the list of possible Electroneutral sodium bicarbonate exchanger products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Electroneutral sodium bicarbonate exchanger 1

 Electroneutral sodium bicarbonate exchanger 1 ELISA Kit
 Electroneutral sodium bicarbonate exchanger 1 Recombinant
 Electroneutral sodium bicarbonate exchanger 1 Antibody
Also known as Electroneutral sodium bicarbonate exchanger 1 (Electroneutral Na(+)-driven Cl-HCO3 exchanger) (Solute carrier family 4 member 8) (k-NBC3).
SLC4A8: Mediates electroneutral sodium- and carbonate-dependent chloride-HCO3(-) exchange with a Na(+):HCO3(-) stoichiometry of 2:1. Plays a major role in pH regulation in neurons. May be involved in cell pH regulation by transporting HCO3(-) from blood to cell. Enhanced expression in severe acid stress could be important for cell survival by mediating the influx of HCO3(-) into the cells. Also mediates lithium-dependent HCO3(-) cotransport
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. May be regulated by osmolarity. Belongs to the anion exchanger (TC 2.A.31) family. 7 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, SLC family

Chromosomal Location of Human Ortholog: 12q13.13

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: anion transmembrane transporter activity; inorganic anion exchanger activity

Biological Process: bicarbonate transport; regulation of intracellular pH
 SLC4A8 ELISA Kit
 SLC4A8 Recombinant
 SLC4A8 Antibody
 KIAA0739 ELISA Kit
 KIAA0739 Recombinant
 KIAA0739 Antibody
 NBC ELISA Kit
 NBC Recombinant
 NBC Antibody
 NBC3 ELISA Kit
 NBC3 Recombinant
 NBC3 Antibody
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