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Elongation factor-like GTPase

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Involved in the biogenesis of the 60S ribosomal subunit and translational activation of ribosomes. Together with SBDS, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Has low intrinsic GTPase activity. GTPase activity is increased by contact with 60S ribosome subunits.

Below are the list of possible Elongation factor-like GTPase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Elongation factor-like GTPase 1

 Elongation factor-like GTPase 1 ELISA Kit
 Elongation factor-like GTPase 1 Recombinant
 Elongation factor-like GTPase 1 Antibody
Also known as Elongation factor-like GTPase 1 (Elongation factor Tu GTP-binding domain-containing protein 1) (Elongation factor-like 1) (Protein FAM42A).
EFTUD1: Involved in the biogenesis of the 60S ribosomal subunit and translational activation of ribosomes. Together with SBDS, triggers the GTP-dependent release of EIF6 from 60S pre-ribosomes in the cytoplasm, thereby activating ribosomes for translation competence by allowing 80S ribosome assembly and facilitating EIF6 recycling to the nucleus, where it is required for 60S rRNA processing and nuclear export. Has low intrinsic GTPase acti
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vity. GTPase activity is increased by contact with 60S ribosome subunits. Belongs to the GTP-binding elongation factor family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Translation; Translation elongation

Chromosomal Location of Human Ortholog: 15q25.2

Cellular Component: intracellular

Molecular Function: GTPase activity; ribosome binding

Biological Process: mature ribosome assembly; translation
 EFL1 ELISA Kit
 EFL1 Recombinant
 EFL1 Antibody
 EFTUD1 ELISA Kit
 EFTUD1 Recombinant
 EFTUD1 Antibody
 FAM42A ELISA Kit
 FAM42A Recombinant
 FAM42A Antibody
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