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Elongation of very long chain fatty acids protein

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Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate in the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Indirectly inhibits RPE65 via production of VLCFAs.

Below are the list of possible Elongation of very long chain fatty acids protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Elongation of very long chain fatty acids protein 1

 Elongation of very long chain fatty acids protein 1 ELISA Kit
 Elongation of very long chain fatty acids protein 1 Recombinant
 Elongation of very long chain fatty acids protein 1 Antibody
Also known as Elongation of very long chain fatty acids protein 1 (3-keto acyl-CoA synthase ELOVL1) (ELOVL fatty acid elongase 1) (ELOVL FA elongase 1) (Very long chain 3-ketoacyl-CoA synthase 1) (Very long chain 3-oxoacyl-CoA synthase 1).
ELOVL1: Condensing enzyme that catalyzes the synthesis of both saturated and monounsaturated very long chain fatty acids. Exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Belongs to the ELO family.

Prot
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ein type: EC 2.3.1.199; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 1p34.2

Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; integral to endoplasmic reticulum membrane; membrane

Molecular Function: fatty acid elongase activity; protein binding

Biological Process: fatty acid elongation, saturated fatty acid; linoleic acid metabolic process; sphingolipid biosynthetic process; very-long-chain fatty acid biosynthetic process
 ELOVL1 ELISA Kit
 ELOVL1 Recombinant
 ELOVL1 Antibody
 SSC1 ELISA Kit
 SSC1 Recombinant
 SSC1 Antibody
 CGI-88 ELISA Kit
 CGI-88 Recombinant
 CGI-88 Antibody
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Elongation of very long chain fatty acids protein 2

 Elongation of very long chain fatty acids protein 2 ELISA Kit
 Elongation of very long chain fatty acids protein 2 Recombinant
 Elongation of very long chain fatty acids protein 2 Antibody
Also known as Elongation of very long chain fatty acids protein 2 (3-keto acyl-CoA synthase ELOVL2) (ELOVL fatty acid elongase 2) (ELOVL FA elongase 2) (Very long chain 3-ketoacyl-CoA synthase 2) (Very long chain 3-oxoacyl-CoA synthase 2).
ELOVL2: Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). Acts specifically toward polyunsatu
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rated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Belongs to the ELO family.

Protein type: EC 2.3.1.199; Lipid Metabolism - unsaturated fatty acid biosynthesis; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 6p24.2

Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; integral to endoplasmic reticulum membrane

Molecular Function: fatty acid elongase activity; protein binding

Biological Process: fatty acid elongation, saturated fatty acid; linoleic acid metabolic process; sphingolipid biosynthetic process; very-long-chain fatty acid biosynthetic process
 ELOVL2 ELISA Kit
 ELOVL2 Recombinant
 ELOVL2 Antibody
 SSC2 ELISA Kit
 SSC2 Recombinant
 SSC2 Antibody
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Elongation of very long chain fatty acids protein 3

 Elongation of very long chain fatty acids protein 3 ELISA Kit
 Elongation of very long chain fatty acids protein 3 Recombinant
 Elongation of very long chain fatty acids protein 3 Antibody
Also known as Elongation of very long chain fatty acids protein 3 (3-keto acyl-CoA synthase Elovl3) (CIN-2) (Cold-inducible glycoprotein of 30 kDa) (ELOVL fatty acid elongase 3) (ELOVL FA elongase 3) (Very long chain 3-ketoacyl-CoA synthase 3) (Very long.
ELOVL3: Condensing enzyme that elongates saturated and monounsaturated very long chain fatty acids (VLCFAs). Highest activity toward C18 acyl
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-CoAs, especially C18:0 acyl-CoAs. Belongs to the ELO family.

Protein type: EC 2.3.1.199; Membrane protein, integral; Membrane protein, multi-pass

Cellular Component: endoplasmic reticulum; integral to endoplasmic reticulum membrane

Molecular Function: fatty acid elongase activity

Biological Process: fatty acid elongation, saturated fatty acid; sphingolipid biosynthetic process; very-long-chain fatty acid biosynthetic process
 Elovl3 ELISA Kit
 Elovl3 Recombinant
 Elovl3 Antibody
 Cig30 ELISA Kit
 Cig30 Recombinant
 Cig30 Antibody
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Elongation of very long chain fatty acids protein 4

 Elongation of very long chain fatty acids protein 4 ELISA Kit
 Elongation of very long chain fatty acids protein 4 Recombinant
 Elongation of very long chain fatty acids protein 4 Antibody
Also known as Elongation of very long chain fatty acids protein 4 (3-keto acyl-CoA synthase ELOVL4) (ELOVL fatty acid elongase 4) (ELOVL FA elongase 4) (Very long chain 3-ketoacyl-CoA synthase 4) (Very long chain 3-oxoacyl-CoA synthase 4).
ELOVL4: Condensing enzyme that elongates saturated and monounsaturated very long chain fatty acids (VLCFAs). Elongates C24:0 and C26:0 acyl-CoAs. Seems to re
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present a photoreceptor- specific component of the fatty acid elongation system residing on the endoplasmic reticulum. May be implicated in docosahexaenoic acid (DHA) biosynthesis, which requires dietary consumption of the essential alpha-linolenic acid and a subsequent series of three elongation steps. May play a critical role in early brain and skin development. Defects in ELOVL4 are the cause of Stargardt disease type 3 (STGD3). STGD is one of the most frequent causes of macular degeneration in childhood. It is characterized by macular dystrophy with juvenile-onset, rapidly progressive course, alterations of the peripheral retina, and subretinal deposition of lipofuscin-like material. STGD3 inheritance is autosomal dominant. Defects in ELOVL4 are the cause of ichthyosis, spastic quadriplegia, and mental retardation (ISQMR). A severe autosomal recessive disorder characterized by ichthyosis apparent from birth, profound psychomotor retardation with essentially no development, spastic quadriplegia, and seizures. Belongs to the ELO family.

Protein type: Cancer Testis Antigen (CTA); EC 2.3.1.199; Endoplasmic reticulum; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 6q14

Cellular Component: endoplasmic reticulum; integral to endoplasmic reticulum membrane

Molecular Function: fatty acid elongase activity; protein binding

Biological Process: fatty acid elongation, saturated fatty acid; sphingolipid biosynthetic process; very-long-chain fatty acid biosynthetic process

Disease: Spinocerebellar Ataxia 34
 ELOVL4 ELISA Kit
 ELOVL4 Recombinant
 ELOVL4 Antibody
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Elongation of very long chain fatty acids protein 5

 Elongation of very long chain fatty acids protein 5 ELISA Kit
 Elongation of very long chain fatty acids protein 5 Recombinant
 Elongation of very long chain fatty acids protein 5 Antibody
Also known as Elongation of very long chain fatty acids protein 5 (3-keto acyl-CoA synthase elo-5) (Very-long-chain 3-oxoacyl-CoA synthase 5).
Condensing enzyme that elongates saturated and monounsaturated very long chain fatty acids (VLCFAs) and monomethyl branched-chain fatty acids (mmBCFAs). Required for the formation of isopentadecanoate (C15iso) and isoheptadecanoate (C17iso).
 elo-5 ELISA Kit
 elo-5 Recombinant
 elo-5 Antibody
 F41H10.7 ELISA Kit
 F41H10.7 Recombinant
 F41H10.7 Antibody
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Elongation of very long chain fatty acids protein 6

 Elongation of very long chain fatty acids protein 6 ELISA Kit
 Elongation of very long chain fatty acids protein 6 Recombinant
 Elongation of very long chain fatty acids protein 6 Antibody
Also known as Elongation of very long chain fatty acids protein 6 (3-keto acyl-CoA synthase elo-6) (Very-long-chain 3-oxoacyl-CoA synthase 6).
Condensing enzyme that elongates saturated and monounsaturated very long chain fatty acids (VLCFAs) and monomethyl branched-chain fatty acids (mmBCFAs). Required for the formation of isoheptadecanoate (C17iso).
 elo-6 ELISA Kit
 elo-6 Recombinant
 elo-6 Antibody
 F41H10.8 ELISA Kit
 F41H10.8 Recombinant
 F41H10.8 Antibody
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Elongation of very long chain fatty acids protein 7

 Elongation of very long chain fatty acids protein 7 ELISA Kit
 Elongation of very long chain fatty acids protein 7 Recombinant
 Elongation of very long chain fatty acids protein 7 Antibody
Also known as Elongation of very long chain fatty acids protein 7 (3-keto acyl-CoA synthase ELOVL7) (ELOVL fatty acid elongase 7) (ELOVL FA elongase 7) (Very long chain 3-ketoacyl-CoA synthase 7) (Very long chain 3-oxoacyl-CoA synthase 7).
ELOVL7: Condensing enzyme that catalyzes the synthesis of saturated and polyunsaturated very long chain fatty acids. Highest activity toward C18 acyl-CoAs, e
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specially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0-, or C26:0-CoAs. Belongs to the ELO family.

Protein type: EC 2.3.1.199; Membrane protein, integral; Membrane protein, multi-pass

Chromosomal Location of Human Ortholog: 5q12.1

Cellular Component: endoplasmic reticulum; endoplasmic reticulum membrane; integral to endoplasmic reticulum membrane

Molecular Function: fatty acid elongase activity; protein binding

Biological Process: fatty acid elongation, saturated fatty acid; sphingolipid biosynthetic process; very-long-chain fatty acid biosynthetic process
 ELOVL7 ELISA Kit
 ELOVL7 Recombinant
 ELOVL7 Antibody
Table BarTOPTable Bar
 

Elongation of very long chain fatty acids protein AAEL008004

 Elongation of very long chain fatty acids protein AAEL008004 ELISA Kit
 Elongation of very long chain fatty acids protein AAEL008004 Recombinant
 Elongation of very long chain fatty acids protein AAEL008004 Antibody
Also known as Elongation of very long chain fatty acids protein AAEL008004 (3-keto acyl-CoA synthase AAEL008004) (Very-long-chain 3-oxoacyl-CoA synthase AAEL008004).
Could be implicated in synthesis of very long chain fatty acids.
 AAEL008004 ELISA Kit
 AAEL008004 Recombinant
 AAEL008004 Antibody
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