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Emerin

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Stabilizes and promotes the formation of a nuclear actin cortical network. Stimulates actin polymerization in vitro by binding and stabilizing the pointed end of growing filaments. Inhibits beta-catenin activity by preventing its accumulation in the nucleus. Acts by influencing the nuclear accumulation of beta-catenin through a CRM1-dependent export pathway. Links centrosomes to the nuclear envelope via a microtubule association. Required for proper localization of non-farnesylated prelamin-A/C (By similarity).

Below are the list of possible Emerin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Emerin

 Emerin ELISA Kit
 Emerin Recombinant
 Emerin Antibody
emerin: a single pass membrane protein that spans the inner nuclear membrane. A serine-rich nuclear membrane protein and a member of the nuclear lamina-associated protein family. It interacts with lamins A and C, and mediates membrane anchorage to the cytoskeleton. Stabilizes and promotes the formation of a nuclear actin cortical network. Stimulates actin polymerization in vitro by binding and sta
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bilizing the pointed end of growing filaments. Inhibits beta-catenin activity by preventing its accumulation in the nucleus. Acts by influencing the nuclear accumulation of beta-catenin through an exportin 1-dependent export pathway. Links centrosomes to the nuclear envelope via a microtubule association. Colocalized with BAF at the central region of the assembling nuclear rim, near spindle-attachment sites. Hyper-phosphorylated on tyrosine in cells overexpressing HER2. Directly phosphorylated by Src and Abl. Phosphorylated by Src at Y59, Y74 and Y95. May function as a downstream effector and signal integrator for tyrosine kinase signaling pathways at the nuclear envelope. Dreifuss-Emery muscular dystrophy is an X-linked inherited degenerative myopathy resulting from mutation in the emerin gene.

Protein type: Cytoskeletal; Membrane protein, integral

Cellular Component: endoplasmic reticulum; integral to membrane; membrane; nuclear envelope; nuclear inner membrane; nuclear membrane; nuclear outer membrane; nucleus; spindle

Molecular Function: actin binding; beta-tubulin binding

Biological Process: negative regulation of fibroblast proliferation; nuclear envelope reassembly; positive regulation of protein export from nucleus
 Emd ELISA Kit
 Emd Recombinant
 Emd Antibody
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Emerin homolog 1

 Emerin homolog 1 ELISA Kit
 Emerin homolog 1 Recombinant
 Emerin homolog 1 Antibody
Also known as Emerin homolog 1 (Ce-emerin).
Involved in chromosome segregation and cell division, probably via its interaction with lmn-1, the main component of nuclear lamina (PubMed:11870211, PubMed:12684533). Has some overlapping function with lem-2 (PubMed:12684533). May play a role in radiation-induced DNA damage repair response (PubMed:22383942).
 emr-1 ELISA Kit
 emr-1 Recombinant
 emr-1 Antibody
 M01D7.6 ELISA Kit
 M01D7.6 Recombinant
 M01D7.6 Antibody
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