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Endoribonuclease

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Toxic component of a type III toxin-antitoxin (TA) module. An endoribonuclease that is probably sequence-specific. It is neutralized by its cognate antitoxin RNA AntiQ, which has 2.8 35 nucleotide-long repeats. Cannot be cloned in L.lactis subsp. cremoris strain NZ9000 in the absence of the antitoxin gene; expression in strain NZ9000 even in the presence of antiQ inhibits growth in a bacteriostatic fashion .

Below are the list of possible Endoribonuclease products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Endoribonuclease AbiQ

 Endoribonuclease AbiQ ELISA Kit
 Endoribonuclease AbiQ Recombinant
 Endoribonuclease AbiQ Antibody
Also known as Endoribonuclease AbiQ (ABIQ) (Toxin AbiQ).
Toxic component of a type III toxin-antitoxin (TA) module. An endoribonuclease that is probably sequence-specific. It is neutralized by its cognate antitoxin RNA AntiQ, which has 2.8 35 nucleotide-long repeats. Cannot be cloned in L.lactis subsp. cremoris strain NZ9000 in the absence of the antitoxin gene; expression in strain NZ9000 even
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in the presence of antiQ inhibits growth in a bacteriostatic fashion (PubMed:23279123). Confers resistance to 936 and c2 phages but not P335 phages in L.lactis, causes an abortive infection (Abi phenotype). Viral DNA is replicated but not cleaved from its concatemeric form, while the viral major structural protein is produced normally in the presence of this protein (PubMed:9835558). Operon expression in E.coli confers resistance to 3 phages of the Myoviridae family (T4, RB69 and phage 2) and 1 of the Siphoviridae family (T5), but not other tested phages (T1, T3, lambda vir, HK97, Mu and pilH alpha). The presence of this operon in L.lactis subsp. lactis strain IL1403 during phage P008 infection alters the viral transcription profiles (PubMed:23813728).
 abiQ ELISA Kit
 abiQ Recombinant
 abiQ Antibody
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Endoribonuclease ChpB

 Endoribonuclease ChpB ELISA Kit
 Endoribonuclease ChpB Recombinant
 Endoribonuclease ChpB Antibody
Also known as Endoribonuclease ChpB (Toxin ChpB) (mRNA interferase ChpB).
Toxic component of a type II toxin-antitoxin (TA) module. ChpB is a sequence-specific mRNA and (weak) tmRNA endoribonuclease that inhibits protein synthesis and induces bacterial stasis. Cleavage is independent of the ribosome. Cleavage occurs at ACY sequences where Y is not C. The endoribonuclease activity is not as strong as that of MazF. The endoribonuclease activity (a toxin) is inhibited by its labile cognate antitoxin ChpS. Toxicity results when the levels of ChpS decrease in the cell, leading to mRNA degradatio
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n. Both ChpS and ChpB probably bind to the promoter region of the chpS-chpB operon to autoregulate their synthesis.
 chpB ELISA Kit
 chpB Recombinant
 chpB Antibody
 chpBK ELISA Kit
 chpBK Recombinant
 chpBK Antibody
 yjfE ELISA Kit
 yjfE Recombinant
 yjfE Antibody
 b4225 ELISA Kit
 b4225 Recombinant
 b4225 Antibody
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Endoribonuclease dcr-1

 Endoribonuclease dcr-1 ELISA Kit
 Endoribonuclease dcr-1 Recombinant
 Endoribonuclease dcr-1 Antibody
Involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway. It produces 21 to 23 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs. Seems to process the precursor of the small temporal RNA let-7 which is involved in developmental timing.
 dcr-1 ELISA Kit
 dcr-1 Recombinant
 dcr-1 Antibody
 K12H4.8 ELISA Kit
 K12H4.8 Recombinant
 K12H4.8 Antibody
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Endoribonuclease Dicer

 Endoribonuclease Dicer ELISA Kit
 Endoribonuclease Dicer Recombinant
 Endoribonuclease Dicer Antibody
Double-stranded RNA (dsRNA) endoribonuclease playing a central role in short dsRNA-mediated post-transcriptional gene silencing. Cleaves naturally occurring long dsRNAs and short hairpin pre-microRNAs (miRNA) into fragments of twenty-one to twenty-three nucleotides with 3' overhang of two nucleotides, producing respectively short interfering RNAs (siRNA) and mature microRNAs. SiRNAs and miRNAs ser
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ve as guide to direct the RNA-induced silencing complex (RISC) to complementary RNAs to degrade them or prevent their translation. Gene silencing mediated by siRNAs, also called RNA interference, controls the elimination of transcripts from mobile and repetitive DNA elements of the genome but also the degradation of exogenous RNA of viral origin for instance. The miRNA pathway on the other side is a mean to specifically regulate the expression of target genes ().
 DICER1 ELISA Kit
 DICER1 Recombinant
 DICER1 Antibody
 DICER ELISA Kit
 DICER Recombinant
 DICER Antibody
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Endoribonuclease Dicer homolog 1

 Endoribonuclease Dicer homolog 1 ELISA Kit
 Endoribonuclease Dicer homolog 1 Recombinant
 Endoribonuclease Dicer homolog 1 Antibody
Also known as Endoribonuclease Dicer homolog 1 (Dicer-like protein 1) (AtDCL1) (Protein ABNORMAL SUSPENSOR 1) (Protein CARPEL FACTORY) (Protein SHORT INTEGUMENTS 1) (Protein SUSPENSOR 1).
Encodes a Dicer homolog. Dicer is a RNA helicase involved in microRNA processing. Mutations in this locus can result in embryo lethality. Embryo shape at seed maturity is globular-elongate. Other mutants convert the floral meristems to an indeterminate state, others yet show defects in ovule development. mRNA is expressed in all shoot tissues. DCL1 is able to produce miRNAs and siRNAs.
 DCL1 ELISA Kit
 DCL1 Recombinant
 DCL1 Antibody
 ASU1 ELISA Kit
 ASU1 Recombinant
 ASU1 Antibody
 CAF ELISA Kit
 CAF Recombinant
 CAF Antibody
 SIN1 ELISA Kit
 SIN1 Recombinant
 SIN1 Antibody
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Endoribonuclease Dicer homolog 2

 Endoribonuclease Dicer homolog 2 ELISA Kit
 Endoribonuclease Dicer homolog 2 Recombinant
 Endoribonuclease Dicer homolog 2 Antibody
Also known as Endoribonuclease Dicer homolog 2 (Dicer-like protein 2) (AtDCL2).
Encodes a Dicer-like protein that functions in the antiviral silencing response in turnip-crinkle virus-infected plants but not in TMV or CMV-strain-Y-infected plants. Involved in the production of ta-siRNAs. Partially antagonizes the production of miRNAs by DCL1. Substitutes for DCL4 to produce viral siRNA when DCL
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4 is missing or inhibited. Able to produce siRNAs but not miRNAs.
 At3g03300 ELISA Kit
 At3g03300 Recombinant
 At3g03300 Antibody
 T17B22.1 ELISA Kit
 T17B22.1 Recombinant
 T17B22.1 Antibody
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Endoribonuclease Dicer homolog 2a

 Endoribonuclease Dicer homolog 2a ELISA Kit
 Endoribonuclease Dicer homolog 2a Recombinant
 Endoribonuclease Dicer homolog 2a Antibody
Also known as Endoribonuclease Dicer homolog 2a (Dicer-like protein 2a) (OsDCL2a).
Probably involved in the RNA silencing pathway. May cleave double-stranded RNA to produce short 21-24 nucleotides (nt) RNAs which target the selective destruction of complementary RNAs ().
 DCL2A ELISA Kit
 DCL2A Recombinant
 DCL2A Antibody
 Os03g0583900 ELISA Kit
 Os03g0583900 Recombinant
 Os03g0583900 Antibody
 LOC_Os03g38740 ELISA Kit
 LOC_Os03g38740 Recombinant
 LOC_Os03g38740 Antibody
 OJ1785_A05.30 ELISA Kit
 OJ1785_A05.30 Recombinant
 OJ1785_A05.30 Antibody
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Endoribonuclease Dicer homolog 2b

 Endoribonuclease Dicer homolog 2b ELISA Kit
 Endoribonuclease Dicer homolog 2b Recombinant
 Endoribonuclease Dicer homolog 2b Antibody
Also known as Endoribonuclease Dicer homolog 2b (Dicer-like protein 2b) (OsDCL2b).
Probably involved in the RNA silencing pathway. May cleave double-stranded RNA to produce short 21-24 nucleotides (nt) RNAs which target the selective destruction of complementary RNAs ().
 DCL2B ELISA Kit
 DCL2B Recombinant
 DCL2B Antibody
 Os09g0315100 ELISA Kit
 Os09g0315100 Recombinant
 Os09g0315100 Antibody
 LOC_Os09g14610 ELISA Kit
 LOC_Os09g14610 Recombinant
 LOC_Os09g14610 Antibody
 OSJNBa0057D11.8-1 ELISA Kit
 OSJNBa0057D11.8-1 Recombinant
 OSJNBa0057D11.8-1 Antibody
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Endoribonuclease Dicer homolog 3

 Endoribonuclease Dicer homolog 3 ELISA Kit
 Endoribonuclease Dicer homolog 3 Recombinant
 Endoribonuclease Dicer homolog 3 Antibody
Also known as Endoribonuclease Dicer homolog 3 (Dicer-like protein 3) (AtDCL3).
Encodes a ribonuclease III family protein that is required for endogenous RDR2-dependent siRNA (but not miRNA) formation.
 DCL3 ELISA Kit
 DCL3 Recombinant
 DCL3 Antibody
 At3g43920 ELISA Kit
 At3g43920 Recombinant
 At3g43920 Antibody
 T15B3.60 ELISA Kit
 T15B3.60 Recombinant
 T15B3.60 Antibody
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Endoribonuclease Dicer homolog 3a

 Endoribonuclease Dicer homolog 3a ELISA Kit
 Endoribonuclease Dicer homolog 3a Recombinant
 Endoribonuclease Dicer homolog 3a Antibody
Also known as Endoribonuclease Dicer homolog 3a (Dicer-like protein 3a) (OsDCL3a).
Probably involved in the RNA silencing pathway. May cleave double-stranded RNA to produce short 21-24 nucleotides (nt) RNAs which target the selective destruction of complementary RNAs ().
 DCL3A ELISA Kit
 DCL3A Recombinant
 DCL3A Antibody
 Os01g0909200 ELISA Kit
 Os01g0909200 Recombinant
 Os01g0909200 Antibody
 LOC_Os01g68120 ELISA Kit
 LOC_Os01g68120 Recombinant
 LOC_Os01g68120 Antibody
 P0456E05.21 ELISA Kit
 P0456E05.21 Recombinant
 P0456E05.21 Antibody
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Endoribonuclease Dicer homolog 3b

 Endoribonuclease Dicer homolog 3b ELISA Kit
 Endoribonuclease Dicer homolog 3b Recombinant
 Endoribonuclease Dicer homolog 3b Antibody
Also known as Endoribonuclease Dicer homolog 3b (Dicer-like protein 3b) (OsDCL3b).
Probably involved in the RNA silencing pathway. May cleave double-stranded RNA to produce short 21-24 nucleotides (nt) RNAs which target the selective destruction of complementary RNAs ().
 DCL3B ELISA Kit
 DCL3B Recombinant
 DCL3B Antibody
 Os10g0485600 ELISA Kit
 Os10g0485600 Recombinant
 Os10g0485600 Antibody
 LOC_Os10g34430 ELISA Kit
 LOC_Os10g34430 Recombinant
 LOC_Os10g34430 Antibody
 OSJNBa0029C15.23 ELISA Kit
 OSJNBa0029C15.23 Recombinant
 OSJNBa0029C15.23 Antibody
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Endoribonuclease Dicer homolog 4

 Endoribonuclease Dicer homolog 4 ELISA Kit
 Endoribonuclease Dicer homolog 4 Recombinant
 Endoribonuclease Dicer homolog 4 Antibody
Also known as Endoribonuclease Dicer homolog 4 (Dicer-like protein 4) (OsDCL4) (Protein SHOOT ORGANIZATION 1).
Involved in the RNA silencing pathway. Cleaves double-stranded RNA to produce small interfering RNAs (siRNAs) which target the selective destruction of complementary RNAs. Required for the production of 21 nucleotide siRNAs. Regulates shoot apical meristem (SAM) initiation and maintenance, leaf polarization and lemma polarity through the trans-acting siRNAS (ta-siRNAs) pathway, which probably modulate the expression of the ARF2, ARF3, ARF4, ARF14 and ARF15 genes. Can process endoge
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nous 21 nucleotide siRNAs derived from an imperfect inverted repeat. May not be involved in microRNAs (miRNAs) production.
 DCL4 ELISA Kit
 DCL4 Recombinant
 DCL4 Antibody
 SHO1 ELISA Kit
 SHO1 Recombinant
 SHO1 Antibody
 Os04g0509300 ELISA Kit
 Os04g0509300 Recombinant
 Os04g0509300 Antibody
 LOC_Os04g43050 ELISA Kit
 LOC_Os04g43050 Recombinant
 LOC_Os04g43050 Antibody
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Endoribonuclease Dicer-like

 Endoribonuclease Dicer-like ELISA Kit
 Endoribonuclease Dicer-like Recombinant
 Endoribonuclease Dicer-like Antibody
Involved in cleaving double-stranded RNA in the RNA interference (RNAi) pathway. It produces 21 to 23 bp dsRNAs (siRNAs) which target the selective destruction of homologous RNAs.
 GL50803_103887 ELISA Kit
 GL50803_103887 Recombinant
 GL50803_103887 Antibody
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Endoribonuclease EndoA

 Endoribonuclease EndoA ELISA Kit
 Endoribonuclease EndoA Recombinant
 Endoribonuclease EndoA Antibody
Also known as Endoribonuclease EndoA (Toxin EndoA) (mRNA interferase EndoA) (mRNA interferase MazF-bs) (MazF-bs).
Toxic component of a type II toxin-antitoxin (TA) module. Specific for 5'-UACAU-3' sequences, cleaving after the first U (PubMed:21763692). Yields cleavage products with 3' phosphate and 5' hydroxyl groups (PubMed:15882409). Cannot digest substrate with a UUdUACAUAA cleavage site (PubMed:24120662). Overexpression is toxic for cell growth (shown in E.coli), probably by inhibiting protein synthesis through the cleavage of single-stranded RNA. The toxicity is reversed by the antito
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xin EndoAI. Toxin activity cannot be inhibited by MazE from E.coli. The EndoA-EndoAI complex does not seem to bind its own promoter (PubMed:24120662).
 ndoA ELISA Kit
 ndoA Recombinant
 ndoA Antibody
 mazF ELISA Kit
 mazF Recombinant
 mazF Antibody
 ydcE ELISA Kit
 ydcE Recombinant
 ydcE Antibody
 BSU04660 ELISA Kit
 BSU04660 Recombinant
 BSU04660 Antibody
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Endoribonuclease GhoS

 Endoribonuclease GhoS ELISA Kit
 Endoribonuclease GhoS Recombinant
 Endoribonuclease GhoS Antibody
Also known as Endoribonuclease GhoS (Antitoxin GhoS).
Antitoxin component of a type V toxin-antitoxin (TA) module. Neutralizes the toxic effects of toxin GhoT by digesting ghoT transcripts in a sequence-specific manner. In concert with GhoT is involved in reducing cell growth during antibacterial stress.
 ghoS ELISA Kit
 ghoS Recombinant
 ghoS Antibody
 Z5730 ELISA Kit
 Z5730 Recombinant
 Z5730 Antibody
 ECs5110 ELISA Kit
 ECs5110 Recombinant
 ECs5110 Antibody
Table BarTOPTable Bar
 

Endoribonuclease HigB

 Endoribonuclease HigB ELISA Kit
 Endoribonuclease HigB Recombinant
 Endoribonuclease HigB Antibody
Also known as Endoribonuclease HigB (Host inhibition of growth protein B) (Killer protein) (Toxin HigB) (mRNA interferase HigB).
Toxic component of a type II toxin-antitoxin (TA) module (PubMed:19423702, PubMed:24257752, PubMed:8645296). A ribosome-associated translation-dependent mRNA interferase. Inhibits translation by sequence-specific cleavage of mRNA. Prefers either in-frame or out-of-fra
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me 5'-AAA-3' codons (lysine). Cleaves also the first three AAAs of stretches of four or more A sequences. 20% of codons containing AA are cleaved and occassionally cuts even at a single A (PubMed:19423702).
 higB ELISA Kit
 higB Recombinant
 higB Antibody
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Endoribonuclease LACTB2

 Endoribonuclease LACTB2 ELISA Kit
 Endoribonuclease LACTB2 Recombinant
 Endoribonuclease LACTB2 Antibody
Also known as Endoribonuclease LACTB2 (Beta-lactamase-like protein 2).
LACTB2: Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.

Protein type: EC 3.-.-.-; Hydrolase; Mitochondrial

Chromosomal Location of Human Ortholog: 8q13.3

Cellular Component: mitochondrial matrix

Molecular Function: endoribonuclease activity; protein binding; single-strande
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d RNA binding; zinc ion binding
 LACTB2 ELISA Kit
 LACTB2 Recombinant
 LACTB2 Antibody
 CGI-83 ELISA Kit
 CGI-83 Recombinant
 CGI-83 Antibody
Table BarTOPTable Bar
 

Endoribonuclease MazF

 Endoribonuclease MazF ELISA Kit
 Endoribonuclease MazF Recombinant
 Endoribonuclease MazF Antibody
Also known as Endoribonuclease MazF (MazFSa) (Toxin MazF) (mRNA interferase MazF).
Toxic component of a type II toxin-antitoxin (TA) module. A sequence-specific endoribonuclease, it cuts between the first and second nucleotides of 5'-UACAU-3' (PubMed:19251861, PubMed:23994560). Cleaves the artifical ssDNA-RNA substrate 5'-AAGTCrUrACATCAG-3' between rU and rA in vitro (PubMed:23994560). Original
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ly found to be a ribosome-independent, with a consensus sequence of 5'-[ACG]UU[ACG]-3' in single-stranded RNA (PubMed:17933891, PubMed:19168622). Its overexpression inhibits protein synthesis and induces bacterial stasis, it is neutralized by coexpression with cognate antitoxin MazE (PubMed:17933891, PubMed:19168622, PubMed:19251861). Not all mRNAs are equally susceptible in vivo (gyrB, recA and sarA for example are not degraded), while no degradation of rRNA has been seen (PubMed:19168622).
 mazF ELISA Kit
 mazF Recombinant
 mazF Antibody
 NWMN_1974 ELISA Kit
 NWMN_1974 Recombinant
 NWMN_1974 Antibody
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Endoribonuclease MazF1

 Endoribonuclease MazF1 ELISA Kit
 Endoribonuclease MazF1 Recombinant
 Endoribonuclease MazF1 Antibody
Also known as Endoribonuclease MazF1 (Toxin MazF1) (mRNA interferase MazF1).
Toxic component of a type II toxin-antitoxin (TA) module. Acts as an endoribonuclease on single-strand RNA, cleaving between the first and second bases in the sequence UCGCU. Neutralized by coexpression with cognate antitoxin MazE1.
 mazF1 ELISA Kit
 mazF1 Recombinant
 mazF1 Antibody
 Mb1532 ELISA Kit
 Mb1532 Recombinant
 Mb1532 Antibody
Table BarTOPTable Bar
 

Endoribonuclease MazF2

 Endoribonuclease MazF2 ELISA Kit
 Endoribonuclease MazF2 Recombinant
 Endoribonuclease MazF2 Antibody
Also known as Endoribonuclease MazF2 (Toxin MazF2) (mRNA interferase MazF2).
Toxic component of a type II toxin-antitoxin (TA) module. Acts as an endoribonuclease on single-strand RNA, cleaving between the second and third bases in the sequences CUCCU and UUCCU. Neutralized by coexpression with cognate antitoxin MazE2.
 mazF2 ELISA Kit
 mazF2 Recombinant
 mazF2 Antibody
 Mb2014c ELISA Kit
 Mb2014c Recombinant
 Mb2014c Antibody
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Endoribonuclease MazF3

 Endoribonuclease MazF3 ELISA Kit
 Endoribonuclease MazF3 Recombinant
 Endoribonuclease MazF3 Antibody
Also known as Endoribonuclease MazF3 (23S rRNA endonuclease MazF3) (Toxin MazF3) (mRNA interferase MazF-mt6).
Toxic component of a type II toxin-antitoxin (TA) module. Acts as an mRNA and 23S rRNA interferase, cleaving predominantly after the first 2 Us in the sequence 5'-UUCCU-3'; in 23S rRNA only cleaves once in the ribosomal A site in dissociated but not intact ribosomes. Cleavage of 23S rRNA inhibits protein translation; the 23S rRNA region cleaved is involved in tRNA-binding in the A site, 30S and 50S subunit interaction and ribosome recycling factor association (PubMed:23650345). Upon
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expression in E.coli and M.smegmatis inhibits cell growth and colony formation. It dramatically increases persister cell formation in M.smegmatis upon challenge with gentamicin or kanamycin. Overexpression leads to bacteriostasis rather than bacteriocide. Its toxic effect is neutralized by coexpression with cognate antitoxin MazE3.
 mazF3 ELISA Kit
 mazF3 Recombinant
 mazF3 Antibody
 mazF-mt6 ELISA Kit
 mazF-mt6 Recombinant
 mazF-mt6 Antibody
 Rv1102c ELISA Kit
 Rv1102c Recombinant
 Rv1102c Antibody
Table BarTOPTable Bar
 

Endoribonuclease MazF4

 Endoribonuclease MazF4 ELISA Kit
 Endoribonuclease MazF4 Recombinant
 Endoribonuclease MazF4 Antibody
Also known as Endoribonuclease MazF4 (Toxin MazF4) (mRNA interferase MazF4).
Toxic component of a type II toxin-antitoxin (TA) module. Acts as an endoribonuclease on single-strand RNA, cleaving between the first and second bases in the sequence UCGCU. Neutralized by cognate antitoxin MazE4.
 mazF4 ELISA Kit
 mazF4 Recombinant
 mazF4 Antibody
 MT1542 ELISA Kit
 MT1542 Recombinant
 MT1542 Antibody
Table BarTOPTable Bar
 

Endoribonuclease MazF6

 Endoribonuclease MazF6 ELISA Kit
 Endoribonuclease MazF6 Recombinant
 Endoribonuclease MazF6 Antibody
Also known as Endoribonuclease MazF6 (Toxin MazF6) (mRNA interferase MazF6).
Toxic component of a type II toxin-antitoxin (TA) module. Acts as an endoribonuclease on single-strand RNA, cleaving between the second and third bases in the sequences CUCCU and UUCCU. Neutralized by coexpression with cognate antitoxin MazE6.
 mazF6 ELISA Kit
 mazF6 Recombinant
 mazF6 Antibody
 MT2046 ELISA Kit
 MT2046 Recombinant
 MT2046 Antibody
Table BarTOPTable Bar
 

Endoribonuclease MazF9

 Endoribonuclease MazF9 ELISA Kit
 Endoribonuclease MazF9 Recombinant
 Endoribonuclease MazF9 Antibody
Also known as Endoribonuclease MazF9 (Toxin MazF9) (mRNA interferase MazF-mt1).
Toxic component of a type II toxin-antitoxin (TA) module. Upon expression in E.coli and M.smegmatis inhibits cell growth and colony formation. Its toxic effect is neutralized by coexpression with cognate antitoxin MazE9. Acts as an mRNA interferase, specifically cleaving between U and C in UAC sequences. May cleave its cognate antitoxin's gene (PubMed:25608501). In E.coli expression with non-cognate antitoxins VapB27 and VapB40 partially neutralizes the toxin.
 mazF9 ELISA Kit
 mazF9 Recombinant
 mazF9 Antibody
 mazF-mt1 ELISA Kit
 mazF-mt1 Recombinant
 mazF-mt1 Antibody
 Rv2801c ELISA Kit
 Rv2801c Recombinant
 Rv2801c Antibody
Table BarTOPTable Bar
 

Endoribonuclease Nob1

 Endoribonuclease Nob1 ELISA Kit
 Endoribonuclease Nob1 Recombinant
 Endoribonuclease Nob1 Antibody
Also known as Endoribonuclease Nob1 (RNase Nob1) (Endonuclease VapC14) (Putative toxin VapC14).
Toxic component of a toxin-antitoxin (TA) module. Processes pre-16S-rRNA at its 3' end (the D-site) to yield the mature 3' end ().
 nob1 ELISA Kit
 nob1 Recombinant
 nob1 Antibody
 vapC14 ELISA Kit
 vapC14 Recombinant
 vapC14 Antibody
 PYRAB13370 ELISA Kit
 PYRAB13370 Recombinant
 PYRAB13370 Antibody
 PAB0882 ELISA Kit
 PAB0882 Recombinant
 PAB0882 Antibody
Table BarTOPTable Bar
 

Endoribonuclease PemK

 Endoribonuclease PemK ELISA Kit
 Endoribonuclease PemK Recombinant
 Endoribonuclease PemK Antibody
Also known as Endoribonuclease PemK (Kid toxin protein) (mRNA interferase PemK).
Toxic component of a type II toxin-antitoxin (TA) module. Probably functions as an endoribonuclease. Responsible for the stable maintenance of the plasmid during cell division by postsegregational killing of plasmid-less daughter cells. Neutralized by coexpression with cognate antitoxin PemI. Both PemI and PemK pro
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teins bind to the promoter region of the pem operon to autoregulate their synthesis.
 pemK ELISA Kit
 pemK Recombinant
 pemK Antibody
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Endoribonuclease RegB

 Endoribonuclease RegB ELISA Kit
 Endoribonuclease RegB Recombinant
 Endoribonuclease RegB Antibody
Also known as Endoribonuclease RegB (Gp61.9).
Essential to the early nucleolytic processing of a number of T4 messenger RNAs. Specifically cleaves after the GG dinucleotide GGAG within consensus 5'-GGAGRAYARAA-3' (R is a purine and Y is a pyrimidine) sequences found mainly in translation initiation sites.
 regB ELISA Kit
 regB Recombinant
 regB Antibody
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Endoribonuclease SymE

 Endoribonuclease SymE ELISA Kit
 Endoribonuclease SymE Recombinant
 Endoribonuclease SymE Antibody
Involved in the degradation and recycling of damaged RNA. It is itself a target for degradation by the ATP-dependent protease Lon.
 symE ELISA Kit
 symE Recombinant
 symE Antibody
 ECH74115_5858 ELISA Kit
 ECH74115_5858 Recombinant
 ECH74115_5858 Antibody
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Endoribonuclease ToxN

 Endoribonuclease ToxN ELISA Kit
 Endoribonuclease ToxN Recombinant
 Endoribonuclease ToxN Antibody
Also known as Endoribonuclease ToxN (EndoRNase) (Toxin ToxN).
Toxic component of a type III toxin-antitoxin (TA) module. An endoribonuclease which is active independently of the ribosome, cleaving between the second and third A of AAA(U/G) sequences, although not all occurrences of this tetranucleotide are cleaved (PubMed:23267117). Digests many mRNA species, including its own transcript and it
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s cognate antitoxin RNA ToxI. ToxI has 5.5 nearly identical 36 nucleotide-long repeats (a single repeat neutralizes the toxin in vivo); a single repeat folds into a pseudoknot which binds the toxin (PubMed:21240270). The ToxI precursor RNA is a preferential target in vivo and is progressively degraded to single repeat lengths as ToxN-ToxI complex self-assembly occurs (PubMed:23267117). In vivo expression of ToxI antitoxin inhibits endonuclease activity of ToxN (PubMed:23267117). The toxin alone inhibits growth when expressed in E.coli without causing cell lysis; this bacteriostatic effect is neutralized by cognate RNA antitoxin ToxI (PubMed:19124776, PubMed:23267117). Non-cognate antitoxin RNA from B.thuringiensis does not inhibit this toxin (PubMed:23267117). The RNA antitoxin is less stable than the proteinaceous toxin; synthesis of ToxI in the absence of new ToxN synthesis restores growth and also detectable accumulation of the ToxN protein (PubMed:19124776). Negatively regulates its own operon in complex with ToxI (PubMed:19633081). The toxin-antitoxin pair function in plasmid maintenance (a plasmid addiction system) (PubMed:23267117).
 toxN ELISA Kit
 toxN Recombinant
 toxN Antibody
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Endoribonuclease VapD

 Endoribonuclease VapD ELISA Kit
 Endoribonuclease VapD Recombinant
 Endoribonuclease VapD Antibody
Also known as Endoribonuclease VapD (Virulence-associated protein D).
Cleaves ssRNA, mostly between U:A.
 vapD ELISA Kit
 vapD Recombinant
 vapD Antibody
 HI_0450 ELISA Kit
 HI_0450 Recombinant
 HI_0450 Antibody
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Endoribonuclease VapD 1

 Endoribonuclease VapD 1 ELISA Kit
 Endoribonuclease VapD 1 Recombinant
 Endoribonuclease VapD 1 Antibody
Also known as Endoribonuclease VapD 1 (Virulence-associated protein 1).
Cleaves ssRNA, mostly between U:A.
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Endoribonuclease VapD 2

 Endoribonuclease VapD 2 ELISA Kit
 Endoribonuclease VapD 2 Recombinant
 Endoribonuclease VapD 2 Antibody
Also known as Endoribonuclease VapD 2 (Virulence-associated protein 2).
Cleaves ssRNA, mostly between U:A.
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Endoribonuclease VapD homolog

 Endoribonuclease VapD homolog ELISA Kit
 Endoribonuclease VapD homolog Recombinant
 Endoribonuclease VapD homolog Antibody
Also known as Endoribonuclease VapD homolog (Virulence-associated protein D homolog).
Cleaves ssRNA, mostly between U:A.
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Endoribonuclease YbeY

 Endoribonuclease YbeY ELISA Kit
 Endoribonuclease YbeY Recombinant
 Endoribonuclease YbeY Antibody
Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
 ybeY ELISA Kit
 ybeY Recombinant
 ybeY Antibody
 ACIAD3160 ELISA Kit
 ACIAD3160 Recombinant
 ACIAD3160 Antibody
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Endoribonuclease YSH1

 Endoribonuclease YSH1 ELISA Kit
 Endoribonuclease YSH1 Recombinant
 Endoribonuclease YSH1 Antibody
Also known as Endoribonuclease YSH1 (mRNA 3'-end-processing protein YSH1).
Component of the cleavage factor I (CF I) involved in pre-mRNA 3'-end processing.
 YSH1 ELISA Kit
 YSH1 Recombinant
 YSH1 Antibody
 CaO19.12941 ELISA Kit
 CaO19.12941 Recombinant
 CaO19.12941 Antibody
 CaO19.5486 ELISA Kit
 CaO19.5486 Recombinant
 CaO19.5486 Antibody
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Endoribonuclease ysh-1

 Endoribonuclease ysh-1 ELISA Kit
 Endoribonuclease ysh-1 Recombinant
 Endoribonuclease ysh-1 Antibody
Also known as Endoribonuclease ysh-1 (mRNA 3'-end-processing protein ysh-1).
Component of the cleavage factor I (CF I) involved in pre-mRNA 3'-end processing.
 ysh-1 ELISA Kit
 ysh-1 Recombinant
 ysh-1 Antibody
 B8L21.110 ELISA Kit
 B8L21.110 Recombinant
 B8L21.110 Antibody
 NCU03479 ELISA Kit
 NCU03479 Recombinant
 NCU03479 Antibody
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Endoribonuclease ZC3H12A

 Endoribonuclease ZC3H12A ELISA Kit
 Endoribonuclease ZC3H12A Recombinant
 Endoribonuclease ZC3H12A Antibody
Also known as Endoribonuclease ZC3H12A (Monocyte chemotactic protein-induced protein 1) (MCP-induced protein 1) (MCPIP-1) (Regnase-1) (Reg1) (Zinc finger CCCH domain-containing protein 12A).
MCPIP1: Has RNase activity and selectively degrades specific target mRNA species. Modulates the immune response and inflammation by regulating the decay of specific mRNA molecules. Recognizes the 3'-untrans
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lated region (UTR) of the mRNA for IL6, CALCR and IL12B. Required for normal decay of IL6 mRNA. Triggers apoptosis and promotes angiogenesis in response to the binding of CCL2 to CCR2. Regulates expression of CDH12 and CHD19. Belongs to the ZC3H12 family.

Protein type: EC 3.1.-.-; Hydrolase

Cellular Component: cytoplasm; cytoskeleton; nucleoplasm; nucleus; plasma membrane; protein complex; rough endoplasmic reticulum

Molecular Function: chromatin binding; DNA binding; endoribonuclease activity; exoribonuclease activity; miRNA binding; mRNA 3'-UTR binding; mRNA binding; ribonuclease activity; ribosome binding; RNA binding; ubiquitin-specific protease activity

Biological Process: cellular response to glucose starvation; inhibition of NF-kappaB transcription factor; mRNA catabolic process, endonucleolytic cleavage-dependent decay; negative regulation of I-kappaB kinase/NF-kappaB cascade; negative regulation of interleukin-1 beta secretion; negative regulation of interleukin-6 production; negative regulation of NF-kappaB import into nucleus; negative regulation of nitric oxide biosynthetic process; negative regulation of protein amino acid phosphorylation; negative regulation of tumor necrosis factor production; positive regulation of angiogenesis; positive regulation of autophagy; positive regulation of defense response to virus by host; positive regulation of fat cell differentiation; positive regulation of protein import into nucleus; positive regulation of transcription from RNA polymerase II promoter; protein deubiquitination; protein oligomerization; regulation of gene expression; response to DNA damage stimulus
 Zc3h12a ELISA Kit
 Zc3h12a Recombinant
 Zc3h12a Antibody
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Proteins Root Name Listing
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