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Endothelin-1 receptor

Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.

Below are the list of possible Endothelin-1 receptor products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.

Endothelin-1 receptor

 Endothelin-1 receptor ELISA Kit
 Endothelin-1 receptor Recombinant
 Endothelin-1 receptor Antibody
Also known as Endothelin-1 receptor (Endothelin A receptor) (ET-A) (ET-AR).
EDNRA: Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol- calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3. Belongs to the G-protein coupled receptor 1 family. Endothelin receptor subfamily. EDNRA
sub-subfamily. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: GPCR, family 1; Membrane protein, integral; Membrane protein, multi-pass; Motility/polarity/chemotaxis; Receptor, GPCR

Cellular Component: lipid raft; membrane; nuclear membrane; T-tubule

Molecular Function: endothelin receptor activity

Biological Process: aging; artery smooth muscle contraction; elevation of cytosolic calcium ion concentration; elevation of cytosolic calcium ion concentration during G-protein signaling, coupled to IP3 second messenger (phospholipase C activating); fibroblast proliferation; glomerular filtration; glucose transport; heart development; histamine secretion; in utero embryonic development; maternal process involved in parturition; negative regulation of apoptosis; negative regulation of cAMP biosynthetic process; neural crest cell development; patterning of blood vessels; penile erection; positive regulation of calcium ion transport; positive regulation of cell proliferation; positive regulation of inflammatory response; positive regulation of odontogenesis; positive regulation of protein amino acid phosphorylation; positive regulation of release of sequestered calcium ion into cytosol; protein kinase C activation; regulation of blood pressure; regulation of epithelial cell proliferation; respiratory gaseous exchange; response to hypoxia; response to lipopolysaccharide; response to morphine; response to organic cyclic substance; Rho protein signal transduction; sensory perception of pain; smooth muscle cell proliferation; vasoconstriction
 Ednra ELISA Kit
 Ednra Recombinant
 Ednra Antibody
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