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Enhancer of polycomb

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Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage (By similarity).

Below are the list of possible Enhancer of polycomb products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Enhancer of polycomb homolog 1

 Enhancer of polycomb homolog 1 ELISA Kit
 Enhancer of polycomb homolog 1 Recombinant
 Enhancer of polycomb homolog 1 Antibody
EPC1: Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for
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the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Belongs to the enhancer of polycomb family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Acetyltransferase; Nuclear envelope

Cellular Component: NuA4 histone acetyltransferase complex; nuclear membrane; nucleoplasm; nucleus

Molecular Function: histone acetyltransferase activity

Biological Process: negative regulation of gene expression, epigenetic; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; positive regulation of striated muscle cell differentiation; positive regulation of transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter
 Epc1 ELISA Kit
 Epc1 Recombinant
 Epc1 Antibody
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Enhancer of polycomb homolog 2

 Enhancer of polycomb homolog 2 ELISA Kit
 Enhancer of polycomb homolog 2 Recombinant
 Enhancer of polycomb homolog 2 Antibody
May play a role in transcription or DNA repair.
 epc2 ELISA Kit
 epc2 Recombinant
 epc2 Antibody
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