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F-actin-uncapping protein

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Cell membrane-cytoskeleton-associated protein that plays a role in the regulation of actin polymerization at the barbed end of actin filaments. Prevents F-actin heterodimeric capping protein (CP) activity at the leading edges of migrating cells, and hence generates uncapped barbed ends and enhances actin polymerization, however, seems unable to nucleate filaments .

Below are the list of possible F-actin-uncapping protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

F-actin-uncapping protein LRRC16A

 F-actin-uncapping protein LRRC16A ELISA Kit
 F-actin-uncapping protein LRRC16A Recombinant
 F-actin-uncapping protein LRRC16A Antibody
Also known as F-actin-uncapping protein LRRC16A (CARMIL homolog) (Capping protein, Arp2/3 and myosin-I linker homolog 1) (Capping protein, Arp2/3 and myosin-I linker protein 1) (CARML1) (Leucine-rich repeat-containing protein 16A).
LRRC16: Binds CAPZA2 with high affinity and significantly decreases CAPZA2 affinity for actin barbed ends. Increases the rate of elongation from seeds in the presence of CAPZA2, however, seems unable to nucleate filaments. Rapidly uncaps barbed ends capped by CAPZA2 and enhances barbed-end actin polymerization. Belongs to the CARMIL family. 4 isoforms of the huma
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n protein are produced by alternative splicing.

Protein type: Unknown function

Cellular Component: cytoplasm; filamentous actin; lamellipodium; leading edge; nucleus; plasma membrane

Molecular Function: protein complex binding

Biological Process: actin filament network formation; barbed-end actin filament uncapping; cell migration; lamellipodium biogenesis; positive regulation of actin filament polymerization; positive regulation of cell migration; positive regulation of stress fiber formation; ruffle organization and biogenesis; urate metabolic process
 Lrrc16a ELISA Kit
 Lrrc16a Recombinant
 Lrrc16a Antibody
 Carmil ELISA Kit
 Carmil Recombinant
 Carmil Antibody
 Lrrc16 ELISA Kit
 Lrrc16 Recombinant
 Lrrc16 Antibody
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