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F-box DNA helicase

3'-5' DNA helicase and substrate-recognition component of the SCF(FBXO18) E3 ubiquitin ligase complex that plays a key role in response to stalled/damaged replication forks (By similarity). Involved in genome maintenance by acting as an anti-recombinogenic helicase and preventing extensive strand exchange during homologous recombination: promotes RAD51 filament dissolution from stalled forks, thereby inhibiting homologous recombination and preventing excessive recombination .

Below are the list of possible F-box DNA helicase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.

F-box DNA helicase 1

 F-box DNA helicase 1 ELISA Kit
 F-box DNA helicase 1 Recombinant
 F-box DNA helicase 1 Antibody
Also known as F-box DNA helicase 1 (F-box only protein 18).
FBXO18: DNA-dependent ATPase. Unwinds double-stranded DNA in a 3' to 5' direction. Belongs to the helicase family. UvrD subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC; Helicase

Cellular Component: chromatin; nucleus; SCF ubiquitin ligase complex

Molecular Function: 3'-5' DNA helicase activity; DNA helicase activity; DNA translocase activity; double-stranded DNA binding; protein binding; single-stranded DNA binding

Biological Process: cell death;
DNA catabolic process, endonucleolytic; positive regulation of protein amino acid phosphorylation; protein ubiquitination; replication fork processing; replication fork protection; response to DNA damage stimulus
 Fbxo18 ELISA Kit
 Fbxo18 Recombinant
 Fbxo18 Antibody
 Fbh1 ELISA Kit
 Fbh1 Recombinant
 Fbh1 Antibody
 Fbx18 ELISA Kit
 Fbx18 Recombinant
 Fbx18 Antibody
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