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F-box-like/WD repeat-containing protein

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F-box-like component of E3 ubiquitin ligase complexes; involved in R7 photoreceptor cell differentiation, cone cell development and neuronal cell cycle control. E3 ubiquitin ligase complexes mediate ubiquitination and subsequent proteasomal degradation of target proteins. Required for specification of R7 photoreceptor cell fate in the eye by participating in the ubiquitination and subsequent proteasomal degradation of Tramtrack (ttk), a general inhibitor of photoreceptor differentiation. Required to block the S phase entry in the peripheral nervous system and central nervous system in a process that does not involve the degradation of ttk. Involved in cone cell development by preventing the transcriptional repression mediated by Su(H) on Dl, probably by participating in a E3 complex that contains sno and mediates the ubiquitination and subsequent proteasomal degradation of some component of the Su(H) repressor complex.

Below are the list of possible F-box-like/WD repeat-containing protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

F-box-like/WD repeat-containing protein ebi

 F-box-like/WD repeat-containing protein ebi ELISA Kit
 F-box-like/WD repeat-containing protein ebi Recombinant
 F-box-like/WD repeat-containing protein ebi Antibody
F-box-like component of E3 ubiquitin ligase complexes; involved in R7 photoreceptor cell differentiation, cone cell development and neuronal cell cycle control. E3 ubiquitin ligase complexes mediate ubiquitination and subsequent proteasomal degradation of target proteins. Required for specification of R7 photoreceptor cell fate in the eye by participating in the ubiquitination and subsequent prote
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asomal degradation of Tramtrack (ttk), a general inhibitor of photoreceptor differentiation. Required to block the S phase entry in the peripheral nervous system and central nervous system in a process that does not involve the degradation of ttk. Involved in cone cell development by preventing the transcriptional repression mediated by Su(H) on Dl, probably by participating in a E3 complex that contains sno and mediates the ubiquitination and subsequent proteasomal degradation of some component of the Su(H) repressor complex.
 ebi ELISA Kit
 ebi Recombinant
 ebi Antibody
 CG4063 ELISA Kit
 CG4063 Recombinant
 CG4063 Antibody
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F-box-like/WD repeat-containing protein TBL1X

 F-box-like/WD repeat-containing protein TBL1X ELISA Kit
 F-box-like/WD repeat-containing protein TBL1X Recombinant
 F-box-like/WD repeat-containing protein TBL1X Antibody
F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of tran
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scription repressor complexes, thereby allowing cofactor exchange ().
 TBL1X ELISA Kit
 TBL1X Recombinant
 TBL1X Antibody
 QtsA-12504 ELISA Kit
 QtsA-12504 Recombinant
 QtsA-12504 Antibody
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F-box-like/WD repeat-containing protein TBL1XR1

 F-box-like/WD repeat-containing protein TBL1XR1 ELISA Kit
 F-box-like/WD repeat-containing protein TBL1XR1 Recombinant
 F-box-like/WD repeat-containing protein TBL1XR1 Antibody
Also known as F-box-like/WD repeat-containing protein TBL1XR1 (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1) (TBL1-related protein 1) (Transducin beta-like 1X-related protein 1).
TBL1XR1: F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of the N-Cor corepressor complex that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradat
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ion of N-Cor complex, thereby allowing cofactor exchange, and transcription activation. Component of the N-Cor repressor complex, at least composed of NCOR1, NCOR2, HDAC3, TBL1X, TBL1XR1, CORO2A and GPS2. Probable component of some E3 ubiquitin ligase complex. Interacts with histones H2B and H4. Ubiquitous. Belongs to the WD repeat EBI family.

Protein type: Nuclear receptor co-regulator; Transcription, coactivator/corepressor

Chromosomal Location of Human Ortholog: 3q26.32

Cellular Component: histone deacetylase complex; nucleoplasm; nucleus; spindle microtubule; transcriptional repressor complex

Molecular Function: beta-catenin binding; histone binding; protein binding; protein N-terminus binding; transcription corepressor activity

Biological Process: cellular lipid metabolic process; histone deacetylation; negative regulation of transcription from RNA polymerase II promoter; positive regulation of transcription from RNA polymerase II promoter; positive regulation of transcription, DNA-dependent; proteasomal ubiquitin-dependent protein catabolic process; Wnt receptor signaling pathway through beta-catenin

Disease: Mental Retardation, Autosomal Dominant 41; Pierpont Syndrome
 TBL1XR1 ELISA Kit
 TBL1XR1 Recombinant
 TBL1XR1 Antibody
 IRA1 ELISA Kit
 IRA1 Recombinant
 IRA1 Antibody
 TBLR1 ELISA Kit
 TBLR1 Recombinant
 TBLR1 Antibody
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F-box-like/WD repeat-containing protein TBL1XR1-A

 F-box-like/WD repeat-containing protein TBL1XR1-A ELISA Kit
 F-box-like/WD repeat-containing protein TBL1XR1-A Recombinant
 F-box-like/WD repeat-containing protein TBL1XR1-A Antibody
Also known as F-box-like/WD repeat-containing protein TBL1XR1-A (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1-A) (TBL1-related protein 1-A) (xTBLR1) (Transducin beta-like 1X-related protein 1-A).
F-box-like protein which acts as an integral component of the N-CoR transcriptional corepressor complex. Probably regulates transcription activation mediated by nuclear receptors. May media
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te the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of the N-CoR complex, thereby allowing cofactor exchange and transcription activation ().
 tbl1xr1-a ELISA Kit
 tbl1xr1-a Recombinant
 tbl1xr1-a Antibody
 tblr1 ELISA Kit
 tblr1 Recombinant
 tblr1 Antibody
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F-box-like/WD repeat-containing protein TBL1XR1-B

 F-box-like/WD repeat-containing protein TBL1XR1-B ELISA Kit
 F-box-like/WD repeat-containing protein TBL1XR1-B Recombinant
 F-box-like/WD repeat-containing protein TBL1XR1-B Antibody
Also known as F-box-like/WD repeat-containing protein TBL1XR1-B (Nuclear receptor corepressor/HDAC3 complex subunit TBLR1-B) (TBL1-related protein 1-B) (Transducin beta-like 1X-related homolog 1-B).
F-box-like protein which acts as an integral component of the N-CoR transcriptional corepressor complex. Probably regulates transcription activation mediated by nuclear receptors. May mediate the re
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cruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of the N-CoR complex, thereby allowing cofactor exchange and transcription activation ().
 tbl1xr1-b ELISA Kit
 tbl1xr1-b Recombinant
 tbl1xr1-b Antibody
 tblr1 ELISA Kit
 tblr1 Recombinant
 tblr1 Antibody
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F-box-like/WD repeat-containing protein TBL1Y

 F-box-like/WD repeat-containing protein TBL1Y ELISA Kit
 F-box-like/WD repeat-containing protein TBL1Y Recombinant
 F-box-like/WD repeat-containing protein TBL1Y Antibody
Also known as F-box-like/WD repeat-containing protein TBL1Y (Transducin beta-like protein 1Y) (Transducin-beta-like protein 1, Y-linked).
TBL1Y: F-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral compo
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nent of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange. Belongs to the WD repeat EBI family.

Chromosomal Location of Human Ortholog: Yp11.2

Cellular Component: histone deacetylase complex

Molecular Function: transcription corepressor activity

Biological Process: histone deacetylation; regulation of transcription from RNA polymerase II promoter
 TBL1Y ELISA Kit
 TBL1Y Recombinant
 TBL1Y Antibody
 TBL1 ELISA Kit
 TBL1 Recombinant
 TBL1 Antibody
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