| FAD-dependent catabolic D-arginine dehydrogenase DauA ELISA Kit|
FAD-dependent catabolic D-arginine dehydrogenase DauA Recombinant
FAD-dependent catabolic D-arginine dehydrogenase DauA Antibody
|Also known as FAD-dependent catabolic D-arginine dehydrogenase DauA (D-arginine dehydrogenase) (DADH) (D-arginine utilization protein A) (Dau). |
DauA is highly expressed within the cystic fibrosis (CF) lung, and it is required for virulence via the optimal production of hydrogen cyanide, pyocyanine, pyoverdine, rhamnolipid and alginate during biofilm formation (PubMed:24011342). Involved in the
catabolism of D-lysine and D-arginine. Under aerobic conditions, the arginine succinyltransferase (AST) and arginine transaminase (ATA) pathways are 2 major routes for L-arginine utilization as the sole source of carbon and nitrogen. The D-to-L racemization of arginine by DauA and DauB is necessary, before to be channeled into the AST and/or ATA pathways. DauA catalyzes the flavin-dependent oxidative deamination of D-arginine into 2-ketoarginine (2-KA) and ammonia (PubMed:3141581, PubMed:19139398, PubMed:19850617, PubMed:20809650). It has also dehydrogenase activity towards D-lysine, D-tyrosine, D-methionine, D-phenylalanine, D-ornithine, D-histidine and D-leucine as substrates (PubMed:19850617, PubMed:20809650).
| dauA ELISA Kit|
| PA3863 ELISA Kit|