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Fanconi anemia group J protein

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DNA-dependent ATPase and 5' to 3' DNA helicase required for the maintenance of chromosomal stability. Acts late in the Fanconi anemia pathway, after FANCD2 ubiquitination. Involved in the repair of DNA double-strand breaks by homologous recombination in a manner that depends on its association with BRCA1.

Below are the list of possible Fanconi anemia group J protein products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Fanconi anemia group J protein

 Fanconi anemia group J protein ELISA Kit
 Fanconi anemia group J protein Recombinant
 Fanconi anemia group J protein Antibody
Also known as Fanconi anemia group J protein (Protein FACJ) (ATP-dependent RNA helicase BRIP1) (BRCA1-associated C-terminal helicase 1) (BRCA1-interacting protein C-terminal helicase 1) (BRCA1-interacting protein 1).
BRIP1: a DNA-dependent ATPase and DNA helicase required for the maintenance of chromosomal stability. Involved in the repair of DNA double-strand breaks by homologous recombination in a manner that depends on its association with BRCA1. Binds directly to the BRCT domains of BRCA1. Defects in BRIP1 cause of susceptibility to breast cancer and Fanconi anemia. Acts late in the Fan
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coni anemia pathway, after FANCD2 ubiquitination. Belongs to the DEAD box helicase family, DEAH subfamily. Two alternatively spliced human isoforms have been described.

Protein type: EC 3.6.4.13; Helicase; Oncoprotein

Chromosomal Location of Human Ortholog: 17q22.2

Cellular Component: cytoplasm; nuclear membrane; nucleoplasm; nucleus

Molecular Function: protein binding

Biological Process: DNA replication; DNA synthesis during DNA repair; regulation of transcription from RNA polymerase II promoter; strand displacement

Disease: Breast Cancer; Fanconi Anemia, Complementation Group J; Tracheoesophageal Fistula With Or Without Esophageal Atresia
 BRIP1 ELISA Kit
 BRIP1 Recombinant
 BRIP1 Antibody
 BACH1 ELISA Kit
 BACH1 Recombinant
 BACH1 Antibody
 FANCJ ELISA Kit
 FANCJ Recombinant
 FANCJ Antibody
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Fanconi anemia group J protein homolog

 Fanconi anemia group J protein homolog ELISA Kit
 Fanconi anemia group J protein homolog Recombinant
 Fanconi anemia group J protein homolog Antibody
Also known as Fanconi anemia group J protein homolog (Protein FACJ) (ATP-dependent RNA helicase BRIP1).
DNA-dependent ATPase and 5' to 3' DNA helicase required for the maintenance of chromosomal stability. Acts late in the 'Fanconi anemia' pathway of DNA repair, after FANCD2 ubiquitination. Probably not involved in the repair of DNA double-strand breaks by homologous recombination.
 BRIP1 ELISA Kit
 BRIP1 Recombinant
 BRIP1 Antibody
 FANCJ ELISA Kit
 FANCJ Recombinant
 FANCJ Antibody
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