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Farnesyl pyrophosphate synthase

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Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate (By similarity).

Below are the list of possible Farnesyl pyrophosphate synthase products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Farnesyl pyrophosphate synthase

 Farnesyl pyrophosphate synthase ELISA Kit
 Farnesyl pyrophosphate synthase Recombinant
 Farnesyl pyrophosphate synthase Antibody
Also known as Farnesyl pyrophosphate synthase (FPP synthase) (FPS) ((2E,6E)-farnesyl diphosphate synthase) (Cholesterol-regulated 39 kDa protein) (CR 39) (Dimethylallyltranstransferase) (Farnesyl diphosphate synthase) (Geranyltranstransferase.
FDPS: Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential met
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abolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate. Belongs to the FPP/GGPP synthase family.

Protein type: EC 2.5.1.1; EC 2.5.1.10; Motility/polarity/chemotaxis; Secondary Metabolites Metabolism - terpenoid backbone biosynthesis; Transferase

Cellular Component: cytoplasm; mitochondrial matrix; mitochondrion; nucleoplasm; peroxisome

Molecular Function: dimethylallyltranstransferase activity; farnesyltranstransferase activity; geranyltranstransferase activity

Biological Process: cholesterol biosynthetic process; farnesyl diphosphate biosynthetic process; isoprenoid biosynthetic process; male gonad development; positive regulation of cholesterol biosynthetic process; response to drug; response to peptide hormone stimulus; response to testosterone stimulus; spermatogenesis
 Fdps ELISA Kit
 Fdps Recombinant
 Fdps Antibody
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Farnesyl pyrophosphate synthase 1

 Farnesyl pyrophosphate synthase 1 ELISA Kit
 Farnesyl pyrophosphate synthase 1 Recombinant
 Farnesyl pyrophosphate synthase 1 Antibody
Also known as Farnesyl pyrophosphate synthase 1 (FPP synthase 1) (FPS 1) ((2E,6E)-farnesyl diphosphate synthase 1) (Dimethylallyltranstransferase 1) (Farnesyl diphosphate synthase 1) (Geranyltranstransferase 1).
Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the
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ultimate product farnesyl pyrophosphate.
 FPS1 ELISA Kit
 FPS1 Recombinant
 FPS1 Antibody
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Farnesyl pyrophosphate synthase 2

 Farnesyl pyrophosphate synthase 2 ELISA Kit
 Farnesyl pyrophosphate synthase 2 Recombinant
 Farnesyl pyrophosphate synthase 2 Antibody
Also known as Farnesyl pyrophosphate synthase 2 (FPP synthase 2) (FPS 2) ((2E,6E)-farnesyl diphosphate synthase 2) (Dimethylallyltranstransferase 2) (Farnesyl diphosphate synthase 2) (Geranyltranstransferase 2).
Encodes a protein with farnesyl diphosphate synthase activity, which catalyzes the rate limiting step in isoprenoid biosynthesis. Its mRNA is most abundantly expressed in flowers.
 FPS2 ELISA Kit
 FPS2 Recombinant
 FPS2 Antibody
 At4g17190 ELISA Kit
 At4g17190 Recombinant
 At4g17190 Antibody
 dl4630c ELISA Kit
 dl4630c Recombinant
 dl4630c Antibody
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Farnesyl pyrophosphate synthase vrtD

 Farnesyl pyrophosphate synthase vrtD ELISA Kit
 Farnesyl pyrophosphate synthase vrtD Recombinant
 Farnesyl pyrophosphate synthase vrtD Antibody
Also known as Farnesyl pyrophosphate synthase vrtD (FPP synthase) (FPS) ((2E,6E)-farnesyl diphosphate synthase) (Dimethylallyltranstransferase) (Farnesyl diphosphate synthase) (Viridicatumtoxin synthesis protein D).
Farnesyl pyrophosphate synthase; part of the gene cluster that mediates the biosynthesis of viridicatumtoxin, a tetracycline-like fungal meroterpenoid with a unique, fused spirobicy
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clic ring system (PubMed:20534346). The first step of the pathway is the production of the malonamoyl-CoA starter unit for the polyketide synthase vrtA (PubMed:20534346). The aldolase vrtJ may be involved in the synthesis of the malonamate substrate for malonamoyl-CoA synthetase vrtB (PubMed:20534346). The polyketide synthase vrtA then may utilize the malonamoyl-CoA starter unit, followed by sequential condensation of eight malonyl-CoA units to form the polyketide backbone (PubMed:20534346). The cyclization of the last ring could be mediated by the lactamase-like protein vrtG (PubMed:20534346). The proposed post-PKS tailoring steps are an hydroxylation at C5 catalyzed the cytochrome P450 monooxygenase vrtE, an hydroxylation at C12a catalyzed by VrtH and/or VrtI, and an O-methylation by the O-methyltransferase vrtF (PubMed:20534346, PubMed:24161266). VrtC is then proposed to catalyze the transfer of a geranyl group synthesized by vrtD to the aromatic C ring of the tetracyclic polyketide intermediate of viridicatumtoxin to yield previridicatumtoxin (PubMed:20534346). Finally, the cytochrome P450 monooxygenase vrtK catalyzes the spirocyclization of the geranyl moeity of previridicatumtoxin to afford viridicatumtoxin (PubMed:24161266).
 vrtD ELISA Kit
 vrtD Recombinant
 vrtD Antibody
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