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FAS-associated factor

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Potentiates but cannot initiate FAS-induced apoptosis.

Below are the list of possible FAS-associated factor products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

FAS-associated factor 1

 FAS-associated factor 1 ELISA Kit
 FAS-associated factor 1 Recombinant
 FAS-associated factor 1 Antibody
FAF1: a pro-apoptotic protein that binds to FAS antigen. Potentiates but cannot initiate FAS-induced apoptosis. Its pro-apoptotic activity requires a ubiquitin-like domain but not the FAS-binding domain. Phosphorylation by protein kinase CK2 influences transport into nucleus. Two transcript variants encoding different protein isoforms have been described.

Protein type: Apoptosis; Nuclear r
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eceptor co-regulator

Cellular Component: cytoplasm; cytosol; nuclear envelope; nucleus; perinuclear region of cytoplasm

Molecular Function: heat shock protein binding; NF-kappaB binding; protein binding; protein domain specific binding; protein kinase binding; ubiquitin binding; ubiquitin protein ligase binding

Biological Process: cell death; cytoplasmic sequestering of NF-kappaB; positive regulation of protein complex assembly; regulation of cell adhesion; regulation of protein catabolic process
 Faf1 ELISA Kit
 Faf1 Recombinant
 Faf1 Antibody
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FAS-associated factor 2

 FAS-associated factor 2 ELISA Kit
 FAS-associated factor 2 Recombinant
 FAS-associated factor 2 Antibody
Also known as FAS-associated factor 2 (Protein ETEA) (UBX domain-containing protein 3B) (UBX domain-containing protein 8).
ETEA: May play a role in the translocation of terminally misfolded proteins from the endoplasmic reticulum lumen to the cytoplasm and their degradation by the proteasome.

Protein type: Endoplasmic reticulum; Ubiquitin conjugating system

Chromosomal Location of Human Ortholog: 5q35.2

Cellular Component: endoplasmic reticulum; lipid particle

Molecular Function: lipase inhibitor activity; protein binding; ubiquitin binding; ubiquitin protein lig
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ase binding

Biological Process: ER-associated protein catabolic process; retrograde protein transport, ER to cytosol
 FAF2 ELISA Kit
 FAF2 Recombinant
 FAF2 Antibody
 ETEA ELISA Kit
 ETEA Recombinant
 ETEA Antibody
 KIAA0887 ELISA Kit
 KIAA0887 Recombinant
 KIAA0887 Antibody
 UBXD8 ELISA Kit
 UBXD8 Recombinant
 UBXD8 Antibody
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FAS-associated factor 2-A

 FAS-associated factor 2-A ELISA Kit
 FAS-associated factor 2-A Recombinant
 FAS-associated factor 2-A Antibody
Also known as FAS-associated factor 2-A (UBX domain-containing protein 8-A).
Plays an important role in endoplasmic reticulum associated degradation (ERAD) that mediates ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Involved in inhibition of lipid droplet degradation.
 faf2-a ELISA Kit
 faf2-a Recombinant
 faf2-a Antibody
 ubxd8-a ELISA Kit
 ubxd8-a Recombinant
 ubxd8-a Antibody
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FAS-associated factor 2-B

 FAS-associated factor 2-B ELISA Kit
 FAS-associated factor 2-B Recombinant
 FAS-associated factor 2-B Antibody
Also known as FAS-associated factor 2-B (UBX domain-containing protein 8-B).
Plays an important role in endoplasmic reticulum associated degradation (ERAD) that mediates ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Involved in inhibition of lipid droplet degradation.
 faf2-b ELISA Kit
 faf2-b Recombinant
 faf2-b Antibody
 ubxd8-b ELISA Kit
 ubxd8-b Recombinant
 ubxd8-b Antibody
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