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Fasciculin

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Interferes with neuromuscular transmission by inhibiting the enzyme acetylcholinesterase (AChE) present at the neuromuscular junction. It selectively binds and inhibits with a 1:1 stoichiometry the mammalian and electric fish AChE at picomolar concentrations. It is highly specific for the peripheral site of AChE and blocks the entry of acetylcholine into the active site of the enzyme, thereby preventing its breakdown. It has been called fasciculin since after injection into mice it causes severe, generalized and long-lasting (5-7 hours) fasciculations.

Below are the list of possible Fasciculin products. If you cannot find the target and/or product is not available in our catalog, please click here to contact us and request the product or submit your request for custom elisa kit production, custom recombinant protein production or custom antibody production. Custom ELISA Kits, Recombinant Proteins and Antibodies can be designed, manufactured and produced according to the researcher's specifications.
 

Fasciculin-1

 Fasciculin-1 ELISA Kit
 Fasciculin-1 Recombinant
 Fasciculin-1 Antibody
Also known as Fasciculin-1 (Fas-1) (Fas1) (Fasciculin-I) (FAS-I) (Toxin TA1).
Interferes with neuromuscular transmission by inhibiting the enzyme acetylcholinesterase (AChE) present at the neuromus
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cular junction. It selectively binds and inhibits with a 1:1 stoichiometry the mammalian and electric fish AChE at picomolar concentrations. It is highly specific for the peripheral site of AChE and blocks the entry of acetylcholine into the active site of the enzyme, thereby preventing its breakdown. It has been called fasciculin since after injection into mice it causes severe, generalized and long-lasting (5-7 hours) fasciculations.
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Fasciculin-2

 Fasciculin-2 ELISA Kit
 Fasciculin-2 Recombinant
 Fasciculin-2 Antibody
Also known as Fasciculin-2 (Fas-2) (Fas2) (Acetylcholinesterase toxin F-VII) (Fasciculin-II) (FAS-II) (Toxin TA1).
Interferes with neuromuscular transmission by inhibiting the enzyme acetylcholines
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terase (AChE) present at the neuromuscular junction. It selectively binds and inhibits with a 1:1 stoichiometry the mammalian and electric fish AChE at picomolar concentrations. It is highly specific for the peripheral site of AChE and blocks the entry of acetylcholine into the active site of the enzyme (through the Met-33 residue), thereby preventing its breakdown. It has been called fasciculin since after injection into mice it causes severe, generalized and long-lasting (5-7 hours) fasciculations.
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